Zusammenfassung
Entzündliche Gelenkerkrankungen sind im Kindesalter insgesamt nicht selten. Sie können nach dem zeitlichen Verlauf unterschieden werden, in akute und chronische Arthritiden sowie in Arthritiden im Rahmen von Systemerkrankungen. Akute Arthritiden schließen die Coxitis fugax und andere postinfektiöse selbstlimitierende Arthritiden ein, aber auch die septische Arthritis, das rheumatische Fieber und die Lyme-Arthritis. Bei der juvenilen idiopathischen Arthritis besteht eine chronische, über zumindest 6 Wochen persistierende Arthritis. Diese heterogenen Erkrankungen werden in 6 Kategorien eingeteilt: Oligoarthritis, rheumafaktorpositive und -negative Polyarthritis, systemische Arthritis/Still-Syndrom, enthesitisassozierte Arthritis und Psoriasisarthritis. Weiterhin kommen Arthritiden bei rheumatischen Systemerkrankungen, bei Vaskulitiden sowie den autoinflammatorischen Erkrankungen vor. Diese Arbeit gibt einen Einblick in die Differenzialdiagose bei Arthritiden im Kindesalter mit einem Hinweis auf die Therapie.
Abstract
Inflammatory joint diseases are not uncommon in childhood. They can be differentiated according to the time course into acute and chronic arthritis as well as arthritis in the context of systemic diseases. Acute arthritis includes transient coxitis fugax and other postinfection self-limiting arthritides and also septic arthritis, rheumatic fever and Lyme arthritis. Juvenile idiopathic arthritis is a chronic arthritis persisting for at least 6 weeks. These heterogeneous diseases are classified into 6 categories, oligoarthritis, rheumatoid factor-positive and rheumatoid factor-negative polyarthritis, systemic arthritis/Still’s disease, enthesitis-related arthritis and psoriatic arthritis. Furthermore, arthritis can be present in systemic rheumatic diseases, vasculitides as well as in autoinflammatory diseases. This review gives an overview of the differential diagnosis in childhood arthritis with remarks on the treatment.
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G. Horneff gibt folgende Interessenkonflikte an: Forschungsunterstützung von Abbvie, Chugai, MSD, Novartis, Pfizer, Roche. Vortragshonorare von Abbvie, Böhringer, Celgen, Chugai, MSD, Novartis, Pfizer.
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Horneff, G. Entzündliche Gelenkerkrankungen. Monatsschr Kinderheilkd 166, 572–584 (2018). https://doi.org/10.1007/s00112-018-0511-5
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DOI: https://doi.org/10.1007/s00112-018-0511-5