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Maternal and cord plasma selenium levels in full term neonates

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Abstract

Selenium is a part of the enzyme glutathione peroxidase and has an important role in the prevention of oxygen free radical injury. Hence good selenium nutrition is of special relevance to the neonate. The present study evaluated plasma selenium levels in cord plasma of 82 full term, appropriate for gestational age babies and their mothers at delivery. The plasma selenium levels in babies were 54.17±1.34 ppb which was significantly lower than 70.63±1.62 ppb seen in their mothers. Anemic mothers with a Hb <8 gJ/dl had a plasma selenium level (60.74±4.57 ppb) which was lower than those with a Hb >8 gJdl i.e. 74.19±2.17 ppb. Maternal age, parity, literacy and socio-economic status did not affect the plasma selenium levels.

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References

  1. Schwartz K, Foltz C. Selenium as an integral part of factor-3 against dietary necrotic liver degeneration.J Am Chem Soc 1957; 79: 3292–3293.

    Article  Google Scholar 

  2. Fleming CR, Lie JT, McCall JF. Selenium deficiency and fatal cardiomyopathy in a patient on home parenteral nutrition.Gastroenterology 1982; 83: 689–693.

    PubMed  CAS  Google Scholar 

  3. Keshan Disease Research Group: Selenium in Heart of China.Lancet 1979; 2 : 889–890.

    Google Scholar 

  4. Litov RE, Comb SGP. Selenium in pediatric nutrition.Pediatrics 1991; 87: 339–351.

    PubMed  CAS  Google Scholar 

  5. Saugstad OD. Oxygen toxicity in the neonatal period.Acta Pediatr Scand 1990; 79: 881–892.

    CAS  Google Scholar 

  6. Volpe JJ. Hypoxic-ischaemic encephalopathy: Biochemical and physiological aspects. In : Volpe JJ, ed.Neurology of the Newborn. 3rd edn. WB Saunders Company; Philadelphia, 1995; 211–259.

    Google Scholar 

  7. Rudolph N, Wong SL. Selenium and glutathione peroxidase activity in maternal and cord plasma and red cells.Pediatr Res 1978; 12: 789–792.

    PubMed  CAS  Google Scholar 

  8. Haga P, Lunde G. Selenium and vitamin E in cord blood from preterm and full term infants.Acta Pediatr Scand 1978; 67: 735–739.

    CAS  Google Scholar 

  9. Bhaskaran P. Micronutrient deficiencies in children-the problem and extent.Indian J Pediatr 1995; 62: 145–156.

    Google Scholar 

  10. Krishnaswamy K. Selenium in human health.ICMR Bulletin 1990; 20(7): 1–4.

    Google Scholar 

  11. Park K. Hospital sociology: Socioeconomic status scale. In : Park K, ed.Park’s Textbook of Preventive and Social Medicine. 15th edn. Jabalpur; Banarsi Dass Bhanot Press, 1997; 458–460.

    Google Scholar 

  12. Ballard J, Novak K, Driver M. A simplified score for assessment of fetal maturation of newly born infants.J Pediatr 1979; 95: 769–774.

    Article  PubMed  CAS  Google Scholar 

  13. Lubchenco L, Hansman C, Boyd E. Intrauterine growth in length and head circumferenoe as estimated from live births at gestational ages from 26 to 42 weeks.Pediatrics 1996; 37: 403–408.

    Google Scholar 

  14. Lombeck I, Papandriou PO, Kamiri F, Laryea MD, Jieng YR, Leitmann P. A screening method for the evaluation of selenium status.J Trace Elem Electrolytes Health Dis 1989; 3: 175–178.

    PubMed  CAS  Google Scholar 

  15. Mahalingam TR, Vijaylakshi S, Krishna Prabhu R, Murthy K, Deepak T. Studies on trace and minor elements in blood — A survey of Kalpakkam (India) Population, Part II: Reference values for plasma and red cells, and correlation with coronary risk index.Biol Trace Elem 1997; 57 : 207–221.

    CAS  Google Scholar 

  16. Bayliss PA, Buchanan BE, Hancock RGV, Zlotkin SH. Tissue selenium accretion in premature and full term human infants and children.Biol Trace Elem Res 1985; 7: 55–61.

    Article  CAS  Google Scholar 

  17. Varo P, Alfthan G, Huttunen JK, Antti A. Nation wide selenium supplementation in Finland. Effect on diet. Blood and tissue levels and health. In: Burk RF, ed.Selenium in Biology and Human Health. New York; Springer Varlag, 1994 : 207–208.

    Google Scholar 

  18. Arnand J, Preziosi P, Masakool, Galan P. Serum Selenium in Zairian mothers and newborn.Eur J Clin Nutr 1994; 48(5): 341–348. ’

    Google Scholar 

  19. Dreosti IE. Selenium.J Food Nutr 1986; 43: 60–66.

    Google Scholar 

  20. Butler JA, Whanger PD, Tripp MJ. Blood selenium and glutathione peroxidase activity in pregnant women-comparative assay in primates and other animals.Am J Clin Nutr 1982; 36: 15–23.

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Pediatrics, Pt. B.D.S. Postgraduate Institute of Medical Sciences, Rohtak

    Geeta Gathwala M.D., O. P. Yadav, Ishwar Singh & Krishna Sangwan

  2. Obstetrics & Gynaecology, Pt. B.D.S. Postgraduate Institute of Medical Sciences, Rohtak

    Krishna Sangwan

  3. Department of Chemistry, Maharshi Dayanand University, Rohtak

    Ishwar Singh

Authors
  1. Geeta Gathwala M.D.
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  2. O. P. Yadav
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  3. Ishwar Singh
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  4. Krishna Sangwan
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Gathwala, G., Yadav, O.P., Singh, I. et al. Maternal and cord plasma selenium levels in full term neonates. Indian J Pediatr 67, 729–731 (2000). https://doi.org/10.1007/BF02723929

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