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Solitary borrelial lymphocytoma: Report of 36 cases

Solitäres Borrelien-Lymphozytom. Bericht über 36 Fälle

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Summary

Thirty-six cases of borrelial lymphocytoma were detected during the period 1986 to 1990 in Slovenia. Borrelial lymphocytoma was located on the ear lobe in 17 persons, ten female and seven male, with a median age of 12 years (range 2–56). Fourteen of these 17 were children under 14 years of age. A tick bite was remembered by 15 patients a median of 30 days before borrelial lymphocytoma developed. The most frequent month of onset was September. Erythema migrans preceded or accompanied borrelial lymphocytoma in eight cases. In 15 cases, eight female and seven male, borrelial lymphocytoma was localized on the mamilla. Median age of these patients was 42 years (range 15–72). Twelve had a tick bite about 45 days (median value) before the onset of borrelial lymphocytoma, which occurred most frequently in August. Erythema migrans was reported in 13 patients and preceded borrelial lymphocytoma in ten cases. In another four patients borrelial lymphocytoma was localized on the nose, scrotum, upper arm and shoulder. Antibiotic treatment with phenoxymethyl-penicillin (n=16), ceftriaxone (n=8), doxycycline (n=9), azithromycin (n=2) and penicillin G (1) led to complete recovery within an average of three weeks in all cases.

Zusammenfassung

Zwischen 1986 und 1990 wurden in Slowenien 36 Patienten mit einem Borrelien-Lymphozytom erfaßt. Bei 17 Patienten, 10 weiblichen und sieben männlichen, mit einem medianen Alter von 12 Jahren war das Borrelien-Lymphozytom am Ohrläppchen lokalisiert. 14 dieser Patienten waren Kinder unter 14 Jahren. 15 der Patienten hatten einen Zeckenstich 45 Tage (Median) vor Manifestation des Borrelien-Lymphozytoms, das am häufigsten im September auftrat. Ein Erythema migrans bestand gleichzeitig oder ging dem Borrelien- Lymphozytom in 8 Fällen voraus. Bei 15 Patienten, acht weiblichen und sieben männlichen, war das Borrelien-Lymphozytom an der Mammille lokalisiert. Das mediane Alter dieser Patienten war 42 Jahre (15–72). Zwölf hatten einen Zeckenstich circa 45 Tage bevor sich ein Borrelien-Lymphozytom entwickelte, das am häufigsten im August auftrat. Bei weiteren vier Patienten war das Borrelien-Lymphozytom auf der Nase, dem Scrotum, Oberarm und Schulter lokalisiert. Eine antibiotische Behandlung mit Phenoxymethylpenicillin (n=16), Ceftriaxon (n=8), Doxycyclin (n=9), Azithromycin (n=2) oder Penicillin (n=1) führte durchschnittlich innerhalb von drei Wochen zur vollständigen Heilung.

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Strle, F., Pleterski-Rigler, D., Cimperman, J. et al. Solitary borrelial lymphocytoma: Report of 36 cases. Infection 20, 201–206 (1992). https://doi.org/10.1007/BF02033059

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