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Histopathology of Human Lyme Borreliosis

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Aspects of Lyme Borreliosis

Abstract

Lyme borreliosis is a disorder affecting many organs including the skin and reticuloendothelial, cardiovascular, nervous and musculoskeletal systems. The causative organism is Borrelia burgdorferi. After infection via a tick bite, a series of events follows in an attempt to destroy the microorganisms or limit its spread to other sites. The early skin lesion around the tickbite shows edema, vascular dilatation, extravasation of erythrocytes and an inflammatory infiltrate of neutrophils. If the causative organisms persist in the skin, the infiltrate shows predominantly lymphocytes and in many circumstances plasma cells.

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Authors
  1. J. De Koning
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  2. P. H. Duray
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Editor information

Editors and Affiliations

  1. Rosenstr.6, 8000, München 2, Germany

    Klaus Weber (Dermatologist in Private Practice) (Dermatologist in Private Practice)

  2. Laboratory of Vectors and Pathogens, Rocky Mountain Laboratories, Department of Health and Human Services, Public Health Service,National Institutes of Health, National Institute of Allergy and Infectious Diseases, 59840, Hamilton, MT, USA

    Willy Burgdorfer Ph.D.,M.D.(h.c.)

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© 1993 Springer-Verlag Berlin Heidelberg

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De Koning, J., Duray, P.H. (1993). Histopathology of Human Lyme Borreliosis. In: Weber, K., Burgdorfer, W., Schierz, G. (eds) Aspects of Lyme Borreliosis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77614-4_6

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  • DOI: https://doi.org/10.1007/978-3-642-77614-4_6

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-77616-8

  • Online ISBN: 978-3-642-77614-4

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