Abstract
Purpose
In Europe, little empirical evidence is available about over-the-counter (OTC) drug consumption and risk perceptions. The objective of this study was to describe consumers’ OTC drug use and perceptions of OTC drug safety in Germany.
Methods
An online survey based on a quota sample with combined strata for age, gender, and education of 300 adult German participants was conducted in June and July 2013. The survey questionnaire covered the participants’ OTC and prescription drug use, risk perceptions of OTC and prescription drugs, package leaflet reading habits, and OTC drug off-label use.
Results
Seven day prevalences of OTC drug use were higher in women (52.0 %) than in men (40.8 %). The risk perception of specific OTC drugs was impacted by the route of administration, the indication, and the drugs’ ingredients. Products for dermal application or plant-based products were considered ‘rather not risky’ by 82.7–96.6 % of the participants, depending on the product. Products for oral use or chemically synthesized substances were considered less safe. While 48.0 % of consumers reported always reading the package leaflet of OTC drugs, 44.5 % reported not reading it if they knew the drug or believed the drug was very safe. People, 60 years and older, reported significantly lower levels of OTC drug off-label use (9.3 %) than younger people (22.0 %).
Conclusions
The 7-day prevalence of OTC drug use in Germany is high, especially among women. Consumers generally have balanced perceptions regarding OTC drug safety. Behaviours and knowledge related to OTC drug use should be considered by health care providers and regulators.
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Acknowledgments
The authors wish to thank IMS Health for kindly having provided information about 30 OTC drugs most commonly sold in Germany and Heike Gerds for proofreading.
Conflict of interest
The study did not receive any external funding. EB has no conflict of interest. EG is running a department that occasionally performs studies for pharmaceutical industries. These companies include Bayer, Celgene, GSK, Mundipharma, Novartis, Sanofi, Sanofi Pasteur MSD, and STADA. EG has been a consultant to Bayer, Nycomed, Teva, GSK, Schwabe and Novartis.
Author contributions
EB and EG conceptualized the study. EB conducted the data analysis and prepared the manuscript, and EG provided substantive intellectual input and critically reviewed the manuscript.
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Barrenberg, E., Garbe, E. Use of over-the-counter (OTC) drugs and perceptions of OTC drug safety among German adults. Eur J Clin Pharmacol 71, 1389–1396 (2015). https://doi.org/10.1007/s00228-015-1929-5
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DOI: https://doi.org/10.1007/s00228-015-1929-5