Skip to main content
  • 1932 Accesses

Zusammenfassung

Größte Gruppe der Antiallergika sind die Hyposensibilisierungsmittel zur allergenspezifischen Immuntherapie bei allergisch bedingten Atemwegskrankheiten. Danach folgen H1-Antihistaminika, die vor allem zur Behandlung des Heuschnupfens, der allergischen Bindehautentzündung und der Urtikaria eingesetzt werden.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 59.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 84.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  • Arzneimittelkommission der deutschen Ärzteschaft (2007): Stellungnahme der AkdÄ zur allergenspezifischen Immuntherapie. Dtsch Ärztebl 104: A 3355–3357

    Google Scholar 

  • Abramson M, Puy R, Weiner J (2003): Allergen immunotherapy for asthma (Cochrane Review).In: The Cochrane Library, Issue 1, 2003. Oxford: Update Software

    Google Scholar 

  • Adkinson NF, Eggleston PA, Eney D, Goldstein EO, Schuberth KC et al. (1997): A controlled trial of immunotherapy for asthma in allergic children. N Engl J Med 336: 324–331

    Article  CAS  PubMed  Google Scholar 

  • Arvidsson MB, Löwhagen O, Rak S (2002): Effect of 2-year placebo-controlled immunotherapy on airway symptoms and medication in patients with birch pollen allergy. J Allergy Clin Immunol 109: 777–783

    Article  CAS  PubMed  Google Scholar 

  • Bousquet J, Hejjaoui A, Clauzel AM, Guerin B, Dhivert H, Skassa-Brociek W, Wichel FB (1988): Specific immunotherapy with a standardized Dermatophagoides pteronyssinus extract. II. Prediction of efficacy of immunotherapy. J Allergy Clin Immunol 82: 971–977

    Article  CAS  PubMed  Google Scholar 

  • Bousquet J, Scheinmann P, Guinnepain MT, Perrin-Fayolle M, Sauvaget J, Tonnel AB et al. (1999): Sublingual-swallow immunotherapy (SLIT) in patients with asthma due to house-dust mites: a double-blind, placebo-controlled study. Allergy 54: 249–260

    Article  CAS  PubMed  Google Scholar 

  • Boyle RJ, Elremeli M, Hockenhull J, Cherry MG, Bulsara MK, Daniels M, Oude Elberink JN (2012): Venom immunotherapy for preventing allergic reactions to insect stings. Cochrane Database Syst Rev. 2012 Oct 17;10:CD00883–8

    Google Scholar 

  • Bundesministerin für Gesundheit (2008): Verordnung über die Ausdehnung der Vorschriften über die Zulassung der Arzneimittel auf Therapieallergene, die für einzelne Personen auf Grund einer Rezeptur hergestellt werden, sowie über Verfahrensregelungen der staatlichen Chargenprüfung (Therapieallergene-Verordnung) vom 7. November 2008. Bundesgesetzblatt 2008 Teil I Nr. 51, Bonn 13. November 2008, Seite 2177-2178. Internet: www.bgbl.de/>Xaver/start.xav?startbk=Bundesanzeiger_BGBl

  • Calderon MA, Alves B, Jacobson M, Hurwitz B, Sheikh A, Durham S (2007): Allergen injection immunotherapy for seasonal allergic rhinitis. Cochrane Database Syst Rev. 2007 Jan 24; (1): CD00193–6

    Google Scholar 

  • Dahl R, Kapp A, Colombo G, de Monchy JG, Rak S, Emminger W, Rivas MF, Ribel M, Durham SR (2006): Efficacy and safety of sublingual immunotherapy with grass allergen tablets for seasonal allergic rhinoconjunctivitis. J Allergy Clin Immunol 118: 434–440

    Article  CAS  PubMed  Google Scholar 

  • Dahl R, Kapp A, Colombo G, de Monchy JG, Rak S, Emminger W, Riis B, Gronager PM, Durham SR (2008): Sublingual grass allergen tablet immunotherapy provides sustained clinical benefit with progressive immunologic changes over 2 years. J Allergy Clin Immunol 121: 512–518

    Article  CAS  PubMed  Google Scholar 

  • Devillier P, Dreyfus JF, Demoly P, Calderon MA (2014): A meta-analysis of sublingual allergen immunotherapy and pharmacotherapy in pollen-induced seasonal allergic rhinoconjunctivitis. BMC Med. 2014 May 1;12:7–1. doi: 10.1186/1741-7015-12-71

    Article  Google Scholar 

  • Didier A, Mailing HJ, Worm M, Horak F, Jäger S, Montagut A, Andre C, Beaumont O de, Melac M (2007): Optimal dose, efficacy, and safety of once-daily sublingual immunotherapy with a 5-grasspollen tablet for seasonal allergic rhinitis. J Allergy Clin Immunol 120: 1338–1345

    Article  CAS  PubMed  Google Scholar 

  • Durham SR, Walker SM, Varga EM, Jacobson MR, O'Brian F, Noble W et al. (1999): Long-term clinical efficacy of grass-pollen immunotherapy. N Engl J Med 341: 468–475

    Article  CAS  PubMed  Google Scholar 

  • Guez S, Vatrinet C, Fadel R, Andre C (2000): House-dust-mite sublingual-swallow immunotherapy (SLIT) in perennial rhinitis: a double-blind, placebo-controlled study. Allergy 55: 36937–5

    Article  Google Scholar 

  • Hoff M, Krail M, Kästner M, Haustein D, Vieths S (2002): Fusarium culmorum causes strong degradation of pollen allergens in extract mixtures. J Allergy Clin Immunol 109: 96–101

    Article  PubMed  Google Scholar 

  • Kiel MA, Röder E, Gerth van Wijk R, Al MJ, Hop WC, Rutten-van Mölken MP (2013): Real-life compliance and persistence among users of subcutaneous and sublingual allergen immu- notherapy. J Allergy Clin Immunol 132: 353–360

    Article  PubMed  Google Scholar 

  • Lüderitz-Püchel U, Keller-Stanislawski B, Haustein D (2001): Neubewertung des Risikos von Test- und Therapieallergenen. Eine Analyse der UAW-Meldungen von 1991 bis 2000. Bundesgesunheitsbl - Gesundheitsforsch - Gesundheitsschutz 44: 709–718

    Article  Google Scholar 

  • Meadows A, Kaambwa B, Novielli N, Huissoon A, Fry-Smith A, Meads C, Barton P, Dretzke J (2013): A systematic review and economic evaluation of subcutaneous and sublingual allergen immunotherapy in adults and children with seasonal allergic rhinitis. Health Technol Assess 17: vi, xi-xiv, 1–322

    Article  Google Scholar 

  • Mellerup MT, Hahn GW, Poulsen LK, Malling HJ (2000): Safety of allergen-specific immuno- therapy. Relation between dosage regimen, allergen extract, disease and systemic side- effects during induction treatment. Clin Exp Allergy. 30: 1423–1429

    Article  CAS  PubMed  Google Scholar 

  • Möller C, Dreborg S, Ferdousi HA, Halken S, Host A, Jacobsen L et al. (2002): Pollen immuno- therapy reduces the development of asthma in children with seasonal rhinoconjunctivitis (the PAT-Study). J Allergy Clin Immunol 109: 251–256

    Article  PubMed  Google Scholar 

  • Nelson HS (2007): Allergen immunotherapy: where is it now? J Allergy Clin Immunol 119: 769–779

    Article  CAS  PubMed  Google Scholar 

  • Olsen OT, Larsen KR, Jacobsan L, Svedsen UG (1997): A 1-year placebo-controlled, double-blind house-dust-mite immunotherapy study in asthmatic adults. Allergy 52: 853–859

    Article  CAS  PubMed  Google Scholar 

  • O'Neill SM, Forsyth A (1988): Urticaria. Prescribers J 28: 14–20

    Google Scholar 

  • Pfaar O, Bachert C, Bufe A, Buhl R, Ebner C, Eng P, Friedrichs F, Fuchs T, Hamelmann E, HartwigBade D, Hering T, Hutteger I, Jung K, Klimek L, Kopp MV, Merk H, Rabe U, Saloga J, Schmid- Grendelmeier P, Schuster A, Schwerk N, Sitter H, Umpfenbach U, Wedi B, Wöhrl S, Worm M, Kleine-Tebbe J (2014): Leitlinie zur (allergen-) spezischen Immuntherapie bei IgE-vermit- telten allergischen Erkrankungen. Allergo J Int 23: 282–319

    Article  PubMed Central  PubMed  Google Scholar 

  • Pfaar O, Jung K, Wolf H, Decot E, Kleine-Tebbe J, Klimek L, Wüstenberg E (2012): Immunologi- cal effects and tolerability of a new fast updosed immunologically enhanced subcutane- ous immunotherapy formulation with optimized allergen/adjuvant ratio. Allergy 67: 630–637

    Article  CAS  PubMed  Google Scholar 

  • Pichler CE, Helbling A, Pichler WJ (2001): Three years of specific immunotherapy with house- dust-mite extracts in patients with rhinitis and asthma: significant improvement of allergen-specific parameters and of nonspecific bronchial hyperreactivity. Allergy 56: 301–306

    Article  CAS  PubMed  Google Scholar 

  • Pichler CE, Marquardsen A, Sparholt S, Lowenstein H, Bircher A, Bischof M, Pichler WJ (1997): Specific immunotherapy with Dermatophagoides ptheronyssinus and D. farinae results in decreased bronchial hyperreactivity. Allergy 52: 274–283

    Article  CAS  PubMed  Google Scholar 

  • Radulovic S, Wilson D, Calderon M, Durham S (2011): Systematic reviews of sublingual immu- notherapy (SLIT). Allergy 66: 740–752

    Article  CAS  PubMed  Google Scholar 

  • Rietschel E, Hutegger I, Lange L, Urbanek R (2013): Anaphylaxie - Diagnostisches und therapeutisches Vorgehen. Med Klin Intensivmed Notfmed 108: 239–249

    Article  CAS  PubMed  Google Scholar 

  • Valsecchi R, di Landro A, Pansera B, Cainelli T (1994): Contact dermatitis from a gel containing dimethindene maleate. Contact Dermatitis 30: 248–249

    Google Scholar 

  • Wheatley LM, Togias A (2015): Clinical practice. Allergic rhinitis. N Engl J Med 372: 456–463

    Article  PubMed Central  PubMed  Google Scholar 

  • Zuberbier T, Bachert C, Bousquet PJ, Passalacqua G, Walter Canonica G, Merk H, Worm M, Wahn U, Bousquet J (2010): GA2 LEN/EAACI pocket guide for allergen-specific immunotherapy for allergic rhinitis and asthma. Allergy 65: 1525–1530

    Article  CAS  PubMed  Google Scholar 

Download references

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2015 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Zawinell, A., Schwabe, U. (2015). Antiallergika. In: Schwabe, U., Paffrath, D. (eds) Arzneiverordnungs-Report 2015. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-47186-9_6

Download citation

  • DOI: https://doi.org/10.1007/978-3-662-47186-9_6

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-47185-2

  • Online ISBN: 978-3-662-47186-9

  • eBook Packages: Medicine (German Language)

Publish with us

Policies and ethics