Zusammenfassung
Entzündungsmuster im Bereich der dermo-epidermalen Junktion. Hierbei dringen zytotoxische Immunzellen basal in das Epithel ein und induzieren den Zelltod von Keratinozyten durch verschiedene Mechanismen. Das IFD-Muster kann sich bei Dermatosen ganz unterschiedlicher Ursache finden: Neben Autoimmunerkrankungen (Lichen planus, Lupus erythematodes, Lichen sclerosus, Dermatomyositis) und reaktiven Krankheitsbildern (Arzneimittelreaktion, Pityriasis lichenoides, GvHD) können auch anti-neoplastische Reaktionen (lichenoide Keratose) sowie frühe anti-Virus-Reaktionen (HSV, Viruswarzen) histologisch ein IFD-Muster präsentieren.
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Wenzel, J. (2016). Entzündliche Dermatosen mit Interface-Dermatitis. In: Cerroni, L., Garbe, C., Metze, D., Kutzner, H., Kerl, H. (eds) Histopathologie der Haut. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-45133-5_9
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