Skip to main content

Histologische Strukturen der normalen Haut

  • Chapter
  • First Online:
Histopathologie der Haut

Part of the book series: Springer Reference Medizin ((SRM))

  • 4593 Accesses

Zusammenfassung

Die Haut ist ein vielfältiges Organ des Menschen, das neben Bindegewebe und hornbildenden Zellen auch Adnexstrukturen, Nerven, Zellen des Immunsystems und Gefäße umfasst. Mit einem Gewicht von ca. 5–10 kg und einer Fläche von etwa 1,6–2 m2 ist sie das größte Organ des menschlichen Organismus. Die Haut besteht im Wesentlichen aus drei Schichten: der Epidermis und Dermis, welche zusammen die Kutis bilden sowie der Subkutis. Die Epidermis wird aus mehreren Schichten von Keratinozyten gebildet, die Dermis, enthält Kollagenfasern, elastische Fasern sowie zahlreiche Blut-und Lymphgefäße. Die Hauptfunktion der Haut besteht in der Bildung der mechanischen Barriere gegenüber exogenen Noxen bei simultanem Austausch verschiedener Substanzen (Kanitakis 2002).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 589.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book
USD 599.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Literatur

  • Amano S (2009) Possible involvement of basement membrane damage in skin photoaging. J Invest Dermatol Symp Proc 14:2–7

    Article  CAS  Google Scholar 

  • Braverman IM (2000) The cutaneous microcirculation. J Investig Dermatol Symp Proc 5(1):3–9

    Article  CAS  PubMed  Google Scholar 

  • Burgeson RE, Christiano AM (1997) The dermal-epidermal junction. Curr Opin Cell Biol 9(5):651–658

    Article  CAS  PubMed  Google Scholar 

  • Caputo R, Peluchetti D (1977) The junctions of normal human epidermis: a freeze-fracture study. J Ultrastruct Res 61(1):44–61

    Article  CAS  PubMed  Google Scholar 

  • Charkoudian N (2003) Skin blood flow in adult human thermoregulation: how it works, when it works, when it does not, and why. Mayo Clin Proc 78(5):603–612

    Article  PubMed  Google Scholar 

  • Chu DH (2008) Overview of biology, development, and structure of skin. In: Wolff K, Goldsmith LA, Katz SI, Gilchrest BA, Paller AS, Leffell DJ (Hrsg) Fitzpatrick’s dermatology in general medicine. 7. Aufl. McGraw-Hill, New York, S 57–73

    Google Scholar 

  • Fuchs E (2007) Scratching the surface of skin development. Nature 445:834–842. doi:10.1038/nature05659

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • James WD, Berger TG, Elston DM (2006) Andrews’ diseases of the skin: clinical dermatology, 10. Aufl. Elsevier Saunders, Philadelphia

    Google Scholar 

  • Jones PH (1996) Isolation and characterization of human epidermal stem cells. Clin Sci 91(2):141–146

    Article  CAS  PubMed  Google Scholar 

  • Kanitakis J (2002) Anatomy, histology and immunohistochemistry of normal human skin. Eur J Dermatol 12(4):390–401

    PubMed  Google Scholar 

  • Krishnaswamy G, Ajitawi O, Chi DS (2006) The human mast cell: an overview. In: Krishnaswamy G, Chi D (Hrsg) Mast cells: methods and protocols, Bd 315, Molecular biology. Humana Press, Totowa, S 13–34

    Chapter  Google Scholar 

  • Lin JY, Fisher DE (2007) Melanocyte biology and skin pigmentation. Nature 445(22):843–850. doi:10.1038/nature05660

    Article  CAS  PubMed  Google Scholar 

  • Lin MS, Mascaro JM Jr, Liu Z, Espana A, Diaz LA (1997) The desmosome and hemidesmosome in cutaneous autoimmunity. Clin Exp Immunol 107(Suppl1):9–15

    CAS  PubMed  Google Scholar 

  • Mauro T, Goldsmith L (2008) Biology of eccrine, apocrine, and apoeccrine sweat glands. In: Wolff K, Goldsmith LA, Katz SI, Gilchrest BA, Paller AS, Leffell DJ (Hrsg) Fitzpatrick’s dermatology in general medicine, 7. Aufl. McGraw-Hill, New York, S 713–720

    Google Scholar 

  • Munger BL, Ide C (1988) The structure and function of cutaneous sensory receptors. Arch Histol Cytol 51(1):1–34

    Article  CAS  PubMed  Google Scholar 

  • Nishiyama T, Amano S, Tsunenaga M, Kadoya K, Takeda A, Adachi Burgeson RE (2000) The importance of laminin 5 in the dermal-epidermal basement membrane. J Dermatol Sci 24(Suppl1):S51–S59

    Article  CAS  PubMed  Google Scholar 

  • Paus R, Cotsarelis G (1999) The biology of hair follicles. N Engl J Med 341(7):491–497

    Article  CAS  PubMed  Google Scholar 

  • Peirce V, Carobbio S, Vidal-Puig A (2014) The different shades of fat. Nature 510(7503):76–83

    Article  CAS  PubMed  Google Scholar 

  • Poblet E, Jiménez F, Ortega F (2004) The contribution of the arrector pili muscle and sebaceous glands to the follicular unit structure. J Am Acad Dermatol 51(2):217–222

    Article  PubMed  Google Scholar 

  • Rabe JH, Mamelak AJ, McElgunn PJ, Morison WL, Sauder DN (2006) Photoaging: mechanisms and repair. J Am Acad Dermatol 55(1):1–19

    Article  PubMed  Google Scholar 

  • Schmidt E, Zillikens D (2010) Modern diagnosis of autoimmune blistering skin diseases. Autoimmun Rev 10(2):84–89

    Article  CAS  PubMed  Google Scholar 

  • Tagami H (2008) Location-related differences in structure and function of the stratum corneum with special emphasis on those of the facial skin. Int J Cosmet Sci 30(6):413–434

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to L. Held .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2016 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Held, L., Metzler, G., Schaller, M. (2016). Histologische Strukturen der normalen Haut. In: Cerroni, L., Garbe, C., Metze, D., Kutzner, H., Kerl, H. (eds) Histopathologie der Haut. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-45133-5_5

Download citation

  • DOI: https://doi.org/10.1007/978-3-662-45133-5_5

  • Published:

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-45132-8

  • Online ISBN: 978-3-662-45133-5

  • eBook Packages: Medicine (German Language)

Publish with us

Policies and ethics