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Nicht infektiöse granulomatöse Dermatitis

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Histopathologie der Haut

Part of the book series: Springer Reference Medizin ((SRM))

Zusammenfassung

Die granulomatösen Dermatosen entsprechen einem entzündlichen Reaktionsmuster der Haut auf unterschiedliche Reize. Sie werden verstanden als Hypersensitivitätsreaktion auf ein nur langsam zu eliminierendes intra- oder extrazellulär lokalisiertes Agens. Eine granulomatöse Entzündung ist durch Makrophagen, Epitheloidzellen und Riesenzellen charakterisiert. Als auslösende Ursache einer nicht erreger-bedingten granulomatösen Reaktion kommen körpereigenes Material, exogene Materialien und autoimmunologische Mechanismen in Betracht. Dabei können gleichartige histologische Veränderungen durch unterschiedliche Ursachen entstehen; andererseits aber kann eine auslösende Ursache auch zu unterschiedlichen histologischen Bildern führen. Um zu einer spezifischen Diagnose zu gelangen, ist daher die klinisch-pathologische Korrelation von besonderer Bedeutung. Die folgende Übersicht fasst die wichtigsten nicht infektiösen granulomatösen Erkrankungen der Haut zusammen sowie die granulomatösen Erkrankungen, die häufiger eine Hautbeteiligung zeigen.

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Authors and Affiliations

  1. HELIOS Klinikum Hildesheim GmbH Klinik für Dermatologie, Venerologie und Allergologie, Weinberg. 1, 31135, Hildesheim, Deutschland

    M. Tronnier

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  1. M. Tronnier
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Correspondence to M. Tronnier .

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Editors and Affiliations

  1. Universitätsklinik für Dermatologie, Medizinische Universität Graz, Graz, Austria

    Lorenzo Cerroni

  2. Universitäts-Hautklinik, Eberhard-Karls-Universität, Tübingen, Germany

    Claus Garbe

  3. Universitäts-Hautklinik Münster, Münster, Germany

    Dieter Metze

  4. Dermatopathologie Friedrichshafen, Friedrichshafen, Germany

    Heinz Kutzner

  5. Universitätsklinik für Dermatologie und, Medizinische Universität Graz, Graz, Steiermark, Austria

    Helmut Kerl

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Tronnier, M. (2016). Nicht infektiöse granulomatöse Dermatitis. In: Cerroni, L., Garbe, C., Metze, D., Kutzner, H., Kerl, H. (eds) Histopathologie der Haut. Springer Reference Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-45133-5_15

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  • DOI: https://doi.org/10.1007/978-3-662-45133-5_15

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