Skip to main content
  • 2684 Accesses

Zusammenfassung

Das Auftreten weiterer autoimmuner Erkrankungen bei Patienten mit Diabetes mellitus Typ 1 (T1D) wird als Ausdruck einer generellen Disposition für Autoimmunität aufgefasst. Auch in etablierten Tiermodellen mit spontaner Entwicklung eines Diabetes mellitus Typ 1 (z. B. Non-obese- diabetic-[NOD-]Maus) wird beobachtet, dass zusätzlich eine Autoimmunthyreoiditis auftritt. Bei Patienten mit Diabetes mellitus Typ 1 treten weitere Autoimmunerkrankungen ca. fünfmal häufiger auf als in der Allgemeinbevölkerung (Baker 2006).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 69.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Literatur

  • Barker JM (2006) Clinical review: Type 1 diabetes-associated autoimmunity: natural history, genetic associations, and screening. J Clin Endocrinol Metab 91: 1210–1217

    Article  CAS  PubMed  Google Scholar 

  • Biondi B, Cooper DS (2008) The clinical significance of subclinical thyroid dysfunction. Endocr Rev 29: 76–131

    Article  CAS  PubMed  Google Scholar 

  • Brown RS (2007) Euthyroid autoimmune thyroiditis in children and adolescents with type 1 diabetes mellitus: to treat or not to treat? Pediatr Diabetes 8: 177–179

    Article  PubMed  Google Scholar 

  • Dorman J, Kramer MK, O’Lear LA et al. (1997) Molecular epidemiology of autoimmune thyroid disease. Gac Med Mex 133 (Suppl 1): 97–103

    PubMed  Google Scholar 

  • Eisenbarth GS, Gottlieb PA (2004) Autoimmune polyendocrine syndromes. N Engl J Med 350: 2068–2079

    Article  CAS  PubMed  Google Scholar 

  • Freemark M (2003) Screening for celiac disease in children with type 1 diabetes. Diabetes Care 26: 1932–1939

    Article  PubMed  Google Scholar 

  • Holt RW, Bohm B, Loos U, Grabert H, Heinze E, Homoki J (1999) Thyroid autoimmunity in children and adolescents with type 1 diabetes mellitus. Effect of age, gender and HLA type. Horm Res 52 (3): 113–118

    Article  Google Scholar 

  • Holterhus PM, Beyer P, Burger-Büsing J et al. (2009) Diagnostik, Therapie und Verlaufskontrolle des Diabetes mellitus im Kindes-und Jugendalter. In: T Haak, M Keller (Hrsg) diabetesDE—Handeln, Helfen, Heilen. http://profi.diabetesde.org/leitlinien. Gesehen 1.9.2009

    Google Scholar 

  • Kabelitz M, Liesenkötter KP, Stach B et al. (2003) The prevalence of anti-thyroid peroxidase antibodies and autoimmune throiditis in children and adolescents in an iodine replete area. Eur J Endocrinol 148 (3): 301–307

    Article  CAS  PubMed  Google Scholar 

  • Karges B, Muche R, Knerr I et al. (2007) Levothyroxine in euthyroid autoimmune thyroiditis and type 1 diabetes: a randomized, controlled trial. J Clin Endocrinol Metab 92: 1647–1652

    Article  CAS  PubMed  Google Scholar 

  • Kordonouri O, Klinghammer A, Lang EB, Grüters-Kieslich A, Grabert M, Holl RW (2002) Thyroid autoimmunitiy in children and adolescents with type 1 diabetes: a multicenter survey. Diabetes Care 25 (8): 1346–1350

    Article  PubMed  Google Scholar 

  • Kordonouri O, Maguire AM, Knip M et al. (2007) Other complications and associated conditions. ISPAD Clinical Practice Consensus Guidelines 2006–2007. Pediatr Diabetes 8: 171–176

    Google Scholar 

  • North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (2005) Guideline for the diagnosis and treatment of celiac disease in children: recommendations of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition. JPGN 40: 1–19

    Google Scholar 

  • Silverstein J, Klingensmith G, Copeland K et al. (2005) Care of children and adolescents with type 1 diabetes. Diabetes Care 28: 186–212

    Article  PubMed  Google Scholar 

  • Völzke H, Lüdemann J, Robinson DM et al. (2003) The prevalence of undiagnosed thyroid disorders in a previously iodine-deficient are. Thyroid 13(8):803–810

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 2010 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Karges, B. (2010). Assoziierte Erkrankungen. In: Pädiatrische Endokrinologie und Diabetologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-01912-8_14

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-01912-8_14

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-01911-1

  • Online ISBN: 978-3-642-01912-8

  • eBook Packages: Medicine (German Language)

Publish with us

Policies and ethics