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Methods of Biological Reconstruction for Bone Sarcoma: Indications and Limits

  • Chapter
Treatment of Bone and Soft Tissue Sarcomas

Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 179))

Abstract

Therapy of bone sarcoma has dramatically changed over the past few decades. Several successful interdisciplinary treatment strategies have led to an increase of the survival rates from 20% to 60%–80%. Consequently new demands on the operative treatment of bone and soft tissue sarcoma have arisen. Nowadays limb salvage can be achieved in 80%–90% using tumour megaprostheses or biological reconstruction procedures. In this article we outline the indications and limitations of biological reconstruction procedures after bone tumour resection. We therefore introduce the different biological approaches such as free autologous bone grafting, reimplantation of extracorporeal devitalized autografts or distraction osteogenesis and summarize the currently available data on the individual procedures. Our analyses demonstrate a wide applicability of biological procedures in tumour situations. Although accompanied by considerable complications in the early postoperative phase, biological reconstructions clearly demonstrate the potential of having excellent long-term durability and functionality.

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Authors and Affiliations

  1. Stiftung Orthopädische Universitätsklinik Heidelberg, Schlierbacher Landstrasse 200a, Heidelberg, 69118, Germany

    Pierre Kunz MD

  2. Städtisches Krankenhaus Bielefeld, Teutoburger Str. 50, Bielefeld, 33604, Germany

    Ludger Bernd MD, PhD

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  1. Pierre Kunz MD
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  2. Ludger Bernd MD, PhD
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  1. Leiter Department Tumororthopädie Klinik für Orthopädie und Orthopädische Rheumatologie, HELIOS-Klinikum Berlin, Schwanebecker Chaussee 50, Berlin, 13125

    Per-Ulf Tunn

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Kunz, P., Bernd, L. (2009). Methods of Biological Reconstruction for Bone Sarcoma: Indications and Limits. In: Tunn, PU. (eds) Treatment of Bone and Soft Tissue Sarcomas. Recent Results in Cancer Research, vol 179. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-77960-5_9

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  • DOI: https://doi.org/10.1007/978-3-540-77960-5_9

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