Skip to main content

Biopsy of Bone and Soft Tissue Tumours: Hints and Hazards

  • Chapter
Treatment of Bone and Soft Tissue Sarcomas

Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 179))

Abstract

Although the diagnostic algorithm of a suspected bone or soft tissue tumour, as well as the biopsy itself, are well defined, avoidable errors still happen. Major flaws might lead to unnecessary tissue contamination resulting in amputations or recurrences. In the current review we will focus in particular on biopsy guidelines and possible biopsy-related problems such as haematomas, sampling errors, and postoperative fractures. Finally, we will provide ten simple rules for a successful biopsy.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

eBook
USD 16.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 119.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Bastiaannet E, Groen H, Jager PL, Cobben DC, vander Graaf WT, Vaalburg W, Hoekstra HJ (2004) The value of FDG-PET in the detection, grading and response to therapy of soft tissue and bone sarcomas; a systematic review and meta-analy- sis. Cancer Treat Rev 30:83–101

    Article  PubMed  CAS  Google Scholar 

  • Bhangu AA, Beard JS, Grimer RJ (2004) Should soft tissue sarcomas be treated at a specialist centre? Sarcoma 8:1–6

    Article  PubMed  CAS  Google Scholar 

  • Bickels J, Jelinek JS, Shmookler BM, Neff RS, Malawer MM (1999) Biopsy of musculoskeletal tumors. Current concepts. Clin Orthop Relat Res 368:212–219

    Google Scholar 

  • Clark CR, Morgan C, Sonstegard DA, Matthews LS (1977) The effect of biopsy-hole shape and size on bone strength. J Bone Joint Surg Am 59:213–217

    PubMed  CAS  Google Scholar 

  • Davies AM, Mehr A, Parsonage S, Evans N, Grimer RJ, Pynsent PB (2004) MR imaging in the assessment of residual tumour following inadequate primary excision of soft tissue sarcomas. Eur Radiol 14:506–513

    Article  PubMed  CAS  Google Scholar 

  • den Heeten GJ, Oldhoff J, Oosterhuis J W, Schraffordt KH (1985) Biopsy of bone tumours. J Surg Oncol 28:247–251

    Article  Google Scholar 

  • Enneking WF, Spanier SS, Goodman MA (1980) A system for the surgical staging of musculoskele- tal sarcoma. Clin Orthop 153:106–120

    PubMed  Google Scholar 

  • Gray JM, Khan MT, Grimer RJ, Pynsent PB (2003) Is fruit a useful indicator of the size of an object? Bull R Coll Surg Engl 85:18–19;33

    Article  Google Scholar 

  • Jaffe HL (1958) Introduction: problems of classification and diagnosis. In: Jaffe HL (ed) Tumors and tumorous conditions of the bones and joints. Lea and Febiger, Philadelphia, pp 9–17

    Google Scholar 

  • Kilpatrick SE, Cappellari JO, Bos G, Gold SH, Ward WG (2001) Is fine-needle aspiration biopsy a practical alternative to open biopsy for the primary diagnosis of sarcoma? Experience with 140 patients. Am J Clin Pathol 115:59–68

    Article  PubMed  CAS  Google Scholar 

  • Kilpatrick SE, Bergman S, Pettenati MJ, Gulley ML (2006) The usefulness of cytogenetic analysis in fine needle aspirates for the histologic subtyping of sarcomas. Mod Pathol 19:815–819

    PubMed  CAS  Google Scholar 

  • Leithner A, Windhager R (2007a) Diagnostik von Tumoren des Stütz- und Bewegungsapparates. Wien Med Wochenschr 157:21–26

    Article  Google Scholar 

  • Leithner A, Windhager R (2007b) Guidelines for the biopsy of bone and soft tissue tumours. Orthopade 36:167–175

    Article  CAS  Google Scholar 

  • Leithner A, Maurer-Ertl W, Glehr M, Beham A, Windhager R (2007) Sampling error at biopsy! Does it still happen? Abstract book of the 20th EMSOS meeting 99

    Google Scholar 

  • Lodwick GS, Wilson AJ, Farrell C, Virtama P, Dittrich F (1980) Determining growth rates of focal lesions of bone from radiographs. Radiology 134:577–583

    PubMed  CAS  Google Scholar 

  • Mankin HJ, Lange TA, Spanier SS (1982) The hazards of biopsy in patients with malignant primary bone and soft-tissue tumors. J Bone Joint Surg Am 64:1121–1127

    PubMed  CAS  Google Scholar 

  • Mankin HJ, Mankin CJ, Simon MA (1996) The hazards of the biopsy, revisited. Members of the Musculoskeletal Tumor Society. J Bone Joint Surg Am 78:656–663

    PubMed  CAS  Google Scholar 

  • Mitsuyoshi G, Naito N, Kawai A, Kunisada T, Yoshida A, Yanai H, Dendo S, Yoshino T, Kanazawa S, Ozaki T (2006) Accurate diagnosis of musculoskel- etal lesions by core needle biopsy. J Surg Oncol 94:21–27

    Article  PubMed  Google Scholar 

  • Schwartz HS, Spengler DM (1997) Needle tract recurrences after closed biopsy for sarcoma: three cases and review of the literature. Ann Surg Oncol 4:228–236

    Article  PubMed  CAS  Google Scholar 

  • Springfield DS, Rosenberg A (1996) Biopsy: complicated and risky. J Bone Joint Surg Am 78:639–643

    PubMed  CAS  Google Scholar 

  • Windhager R, Kastner N, Leithner A (2006) Benigne Knochentumoren und tumorähnliche Läsionen. Monatsschr Kinderhlkd 154:20–31

    Article  Google Scholar 

  • Zacherl M, Leithner A, Koch H, Windhager R (2006) Weichteilsarkome—jeder zweite Patient primär inadäquat therapiert. Wiener Klin Magazin 1:22–28

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2009 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Leithner, A., Maurer-Ertl, W., Windhager, R. (2009). Biopsy of Bone and Soft Tissue Tumours: Hints and Hazards. In: Tunn, PU. (eds) Treatment of Bone and Soft Tissue Sarcomas. Recent Results in Cancer Research, vol 179. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-77960-5_1

Download citation

  • DOI: https://doi.org/10.1007/978-3-540-77960-5_1

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-77959-9

  • Online ISBN: 978-3-540-77960-5

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics