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Non-Surgical Risk Factors for Recurrence of Hernia

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Recurrent Hernia

Abstract

Abdominal wall hernias may recur as long as 15 years after herniotomy. Recurrences which appear within 6 months following surgery are regarded as technical failures due to inadequate surgical technique. Recurrences which appear later than 6–9 months after the primary surgical procedure may be considered as a result of the abnormal collagen metabolism, which originally led to herniation [1, 2].

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References

  1. Peacock EE Jr, Madden JW (1974) Studies on the biology and treatment of recurrent inguinal hernia. II. Morphological changes. Ann Surg 179: 567–571

    Article  PubMed  Google Scholar 

  2. Friedman DW, Boyd CD, Norton P, et al. (1993) Increases in type III collagen gene expression and protein synthesis in patients with inguinal hernias. Ann Surg 218: 754–760

    Article  PubMed  CAS  Google Scholar 

  3. Liem MS, van der G Y, Beemer FA, van Vroonhoven TJ (1997) Increased risk for inguinal hernia in patients with Ehlers-Danlos syndrome. Surgery 122: 114–115

    Article  PubMed  CAS  Google Scholar 

  4. Hayakawa A, Fujimoto K, Ibayashi H (1982) Two cases of Ehlers-Danlos syndrome with gastrointestinal complications. Gastroenterol Jpn 17: 61–67

    PubMed  CAS  Google Scholar 

  5. Abrahamson J (1998) Etiology and pathophysiology of primary and recurrent groin hernia formation. Surg Clin North Am 78: 953–72

    Article  PubMed  CAS  Google Scholar 

  6. Uden A, Lindhagen T (1988) Inguinal hernia in patients with congenital dislocation of the hip. A sign of general connective tissue disorder. Acta Orthop Scand 59: 667–668

    Article  PubMed  CAS  Google Scholar 

  7. Girotto JA, Malaisrie SC, Bulkely G, Manson PN (2000) Recurrent ventral herniation in Ehlers-Danlos syndrome. Plast Reconstr Surg 106: 1520–1526

    Article  PubMed  CAS  Google Scholar 

  8. Abramson JH, Gofin J, Hopp C, Makler A, Epstein LM (1978) The epidemiology of inguinal hernia. A survey in western Jerusalem. J Epidemiol Community Health 32: 59–67

    Article  PubMed  CAS  Google Scholar 

  9. Ashcroft GS, Horan MA, Herrick SE, Tarnuzzer RW, Schultz GS, Ferguson MW (1997) Age-related differences in the temporal and spatial regulation of matrix metalloproteinases (MMPs) in normal skin and acute cutaneous wounds of healthy humans. Cell Tissue Res 290: 581–591

    Article  PubMed  CAS  Google Scholar 

  10. Ashcroft GS, Herrick SE, Tarnuzzer RW, Horan MA, Schultz GS, Ferguson MW (1997) Human ageing impairs injury-induced in vivo expression of tissue inhibitor of matrix metalloproteinases (TIMP)-1 and-2 proteins and mRNA. J Pathol 183: 169–176

    Article  PubMed  CAS  Google Scholar 

  11. Sorensen LT, Friis E, Jorgensen T, Vennits B, Andersen BR, Rasmussen GI, et al. (2002) Smoking is a risk factor for recurrence of groin hernia. World J Surg 26: 397–400

    Article  PubMed  Google Scholar 

  12. Sauerland S, Schmedt CG, Lein S, Leibl BJ, Bittner R (2005) Primary incisional hernia repair with or without polypropylene mesh: a report on 384 patients with 5-year follow-up. Langenbecks Arch Surg 390: 408–412

    Article  PubMed  Google Scholar 

  13. Conner WT, Peacock EE Jr (1973) Some studies on the etiology of inguinal hernia. Am J Surg 126: 732–735

    Article  PubMed  CAS  Google Scholar 

  14. Menck J, Lierse W (1991) The fascia of the inguinal canal ring. Chirurg 62: 117–120

    PubMed  CAS  Google Scholar 

  15. Stelzner F (1994) Function of the abdominal wall and development and therapy of hernias (among others: the paracolostomy hernia). Langenbecks Arch Chir 379: 109–119

    PubMed  CAS  Google Scholar 

  16. McArdle G (1997) Is inguinal hernia a defect in human evolution and would this insight improve concepts for methods of surgical repair? Clin Anat 10: 47–55

    Article  PubMed  CAS  Google Scholar 

  17. Lenhardt R, Hopf HW, Marker E, et al. (2000) Perioperative collagen deposition in elderly and young men and women. Arch Surg 135: 71–74

    Article  PubMed  CAS  Google Scholar 

  18. Jorgensen LN, Sorensen LT, Kallehave F, Vange J, Gottrup F (2002) Premenopausal women deposit more collagen than men during healing of an experimental wound. Surgery 131: 338–343

    Article  PubMed  Google Scholar 

  19. Ashcroft GS, Greenwell-Wild T, Horan MA, Wahl SM, Ferguson MW (1999) Topical estrogen accelerates cutaneous wound healing in aged humans associated with an altered inflammatory response. Am J Pathol 155: 1137–1146

    PubMed  CAS  Google Scholar 

  20. Bucknall TE, Cox PJ, Ellis H (1982) Burst abdomen and incisional hernia: a prospective study of 1129 major laparotomies. Br Med J (Clin Res Ed) 284: 931–933

    CAS  Google Scholar 

  21. Sorensen LT, Hemmingsen UB, Kirkeby LT, Kallehave F, Jorgensen LN (2005) Smoking is a risk factor for incisional hernia. Arch Surg 140: 119–123

    Article  PubMed  Google Scholar 

  22. Hall KA, Peters B, Smyth SH, et al. (1995) Abdominal wall hernias in patients with abdominal aortic aneurysmal versus aortoiliac occlusive disease. Am J Surg 170: 572–575

    Article  PubMed  CAS  Google Scholar 

  23. Raffetto JD, Cheung Y, Fisher JB, et al. (2003) Incision and abdominal wall hernias in patients with aneurysm or occlusive aortic disease. J Vasc Surg 37: 1150–1154

    Article  PubMed  Google Scholar 

  24. Lehnert B, Wadouh F (1992) High coincidence of inguinal hernias and abdominal aortic aneurysms. Ann Vasc Surg 6: 134–137

    Article  PubMed  CAS  Google Scholar 

  25. Adye B, Luna G (1998) Incidence of abdominal wall hernia in aortic surgery. Am J Surg 175: 400–402

    PubMed  CAS  Google Scholar 

  26. Cannon DJ, Casteel L, Read RC (1984) Abdominal aortic aneurysm, Leriche’s syndrome, inguinal herniation, and smoking. Arch Surg 1119: 387–389

    PubMed  CAS  Google Scholar 

  27. Stevick CA, Long JB, Jamasbi B, Nash M (1988) Ventral hernia following abdominal aortic reconstruction. Am Surg 54: 287–289

    PubMed  CAS  Google Scholar 

  28. Augestad KM, Wilsgaard T, Solberg S (2002) Incisional hernia after surgery for abdominal aortic aneurysm. Tidsskr Nor Laegeforen 122: 22–24

    PubMed  Google Scholar 

  29. Holland AJ, Castleden WM, Norman PE, Stacey MC (1996) Incisional hernias are more common in aneurysmal arterial disease. Eur J Vasc Endovasc Surg 12: 196–200

    Article  PubMed  CAS  Google Scholar 

  30. Bellon JM, Bujan J, Honduvilla NG, et al. (1997) Study of biochemical substrate and role of metalloproteinases in fascia transversalis from hernial processes. Eur J Clin Invest 27: 510–516

    Article  PubMed  CAS  Google Scholar 

  31. Bellon JM, Bajo A, Ga-Honduvilla N, et al. (2001) Fibroblasts from the transversalis fascia of young patients with direct inguinal hernias show constitutive MMP-2 overexpression. Ann Surg 233: 287–291

    Article  PubMed  CAS  Google Scholar 

  32. Carbonell JF, Sanchez JL, Peris RT, et al. (1993) Risk factors associated with inguinal hernias: a case control study. Eur J Surg 159: 481–486

    PubMed  CAS  Google Scholar 

  33. Flich J, Alfonso JL, Delgado F, Prado MJ, Cortina P (1992) Inguinal hernia and certain risk factors. Eur J Epidemiol 8: 277–282

    Article  PubMed  CAS  Google Scholar 

  34. Clark JL (2001) Ventral incisional hernia recurrence. J Surg Res 99: 33–39

    Article  PubMed  CAS  Google Scholar 

  35. Bielecki K, Pulawski R (1988) Is cigarette smoking a causative factor in the development of inguinal hernia? Pol Tyg Lek 43: 974–976

    PubMed  CAS  Google Scholar 

  36. Cannon DJ, Read RC (1981) Metastatic emphysema: a mechanism for acquiring inguinal herniation. Ann Surg 194: 270–278

    Article  PubMed  CAS  Google Scholar 

  37. Vardulaki KA, Walker NM, Day NE, Duffy SW, Ashton HA, Scott RA (2000) Quantifying the risks of hypertension, age, sex and smoking in patients with abdominal aortic aneurysm. Br J Surg 87: 195–200

    Article  PubMed  CAS  Google Scholar 

  38. Lindholt JS, Jorgensen B, Klitgaard NA, Henneberg EW (2003) Systemic levels of cotinine and elastase, but not pulmonary function, are associated with the progression of small abdominal aortic aneurysms. Eur J Vasc Endovasc Surg 26: 418–422

    Article  PubMed  CAS  Google Scholar 

  39. Janoff A (1985) Elastases and emphysema. Current assessment of the protease-antiprotease hypothesis. Am Rev Respir Dis 132: 417–433

    PubMed  CAS  Google Scholar 

  40. van Laarhoven CJ, Borstlap AC, Berge Henegouwen DP, Palmen FM, Verpalen MC, Schoemaker MC (1993) Chronic obstructive pulmonary disease and abdominal aortic aneurysms. Eur J Vasc Surg 7: 386–390

    Article  PubMed  Google Scholar 

  41. Knuutinen A, Kokkonen N, Risteli J, et al. (2002) Smoking affects collagen synthesis and extracellular matrix turnover in human skin. Br J Dermatol 146: 588–594

    Article  PubMed  CAS  Google Scholar 

  42. Sorensen LT, Nielsen HB, Kharazmi A, Gottrup F (2004) Effect of smoking and abstention on oxidative burst and reactivity of neutrophils and monocytes. Surgery 136: 1047–1053

    Article  PubMed  Google Scholar 

  43. Jorgensen LN, Kallehave F, Christensen E, Siana JE, Gottrup F (1998) Less collagen production in smokers. Surgery 123: 450–455

    PubMed  CAS  Google Scholar 

  44. Pans A, Pierard GE, Albert A, Desaive C (1997) Adult groin hernias: new insight into their biomechanical characteristics. Eur J Clin Invest 27: 863–868

    Article  PubMed  CAS  Google Scholar 

  45. Pans A, Albert A, Lapiere CM, Nusgens B (2001) Biochemical study of collagen in adult groin hernias. J Surg Res 95: 107–113

    Article  PubMed  CAS  Google Scholar 

  46. Rodrigues Junior AJ, Rodrigues CJ, da Cunha AC, Jin Y (2002) Quantitative analysis of collagen and elastic fibers in the transversalis fascia in direct and indirect inguinal hernia. Rev Hosp Clin Fac Med Sao Paulo 57: 265–270

    PubMed  Google Scholar 

  47. Wagh PV, Leverich AP, Sun CN, White HJ, Read RC (1974) Direct inguinal herniation in men: a disease of collagen. J Surg Res 17: 425–433

    Article  PubMed  CAS  Google Scholar 

  48. Baradi AF, Heslop JH, Rao NS (1986) Peritoneal fine structure of inguinal hernia: a scanning electron microscope study. Histol Histopathol 1: 89–92

    PubMed  CAS  Google Scholar 

  49. Baradi AF, Parry BR, Heslop JH (1992) Peritoneal fine structure of inguinal hernia: a transmission electron microscope study. Histol Histopathol 7: 251–257

    PubMed  CAS  Google Scholar 

  50. Rodrigues Junior AJ, de Tolosa EM, de Carvalho CA (1990) Electron microscopic study on the elastic and elastic related fibres in the human fascia transversalis at different ages. Gegenbaurs Morphol Jahrb 136: 645–652

    PubMed  CAS  Google Scholar 

  51. White HJ, Sun CN, Read RC (1977) Inguinal hernia: a true collagen disease. Lab Invest 36: 359

    Google Scholar 

  52. Wagh PV, Read RC (1971) Attenuation of the rectus sheath in inguinal herniation. Proc Soc Exp Biol Med 137: 382–384

    CAS  Google Scholar 

  53. Wagh PV, Read RC (1972) Defective collagen synthesis in inguinal herniation. Am J Surg 124: 819–822

    Article  PubMed  CAS  Google Scholar 

  54. Klinge U, Zheng H, Si ZY, Schumpelick V, Bhardwaj R, Klosterhalfen B (1999) Synthesis of type I and III collagen, expression of fibronectin and matrix metalloproteinases-1 and-13 in hernial sac of patients with inguinal hernia. Int J Surg Investig 1: 219–227

    PubMed  CAS  Google Scholar 

  55. Klinge U, Zheng H, Si Z, et al. (1999) Expression of the extracellular matrix proteins collagen I, collagen III and fibronectin and matrix metalloproteinase-1 and-13 in the skin of patients with inguinal hernia. Eur Surg Res 31: 480–490

    Article  PubMed  CAS  Google Scholar 

  56. Klinge U, Si ZY, Zheng H, Schumpelick V, Bhardwaj RS, Klosterhalfen B (2000) Abnormal collagen I to III distribution in the skin of patients with incisional hernia. Eur Surg Res 32: 43–48

    Article  PubMed  CAS  Google Scholar 

  57. Klinge U, Si ZY, Zheng H, Schumpelick V, Bhardwaj RS, Klosterhalfen B (2001) Collagen I/III and matrix metalloproteinases (MMP) 1 and 13 in the fascia of patients with incisional hernias. J Invest Surg 14: 47–54

    Article  PubMed  CAS  Google Scholar 

  58. Rosch R, Klinge U, Si Z, Junge K, Klosterhalfen B, Schumpelick V (2002) A role for the collagen I/III and MMP-1/-13 genes in primary inguinal hernia? BMC Med Genet 3: 2

    Article  PubMed  Google Scholar 

  59. Si Z, Bhardwaj R, Rosch R, Mertens PR, Klosterhalfen B, Klinge U (2002) Impaired balance of type I and type III procollagen mRNA in cultured fibroblasts of patients with incisional hernia. Surgery 131: 324–331

    Article  PubMed  Google Scholar 

  60. Rosch R, Junge K, Knops M, Lynen P, Klinge U, Schumpelick V (2003) Analysis of collagen-interacting proteins in patients with incisional hernias. Langenbecks Arch Surg 387: 427–432

    PubMed  CAS  Google Scholar 

  61. Zheng H, Si Z, Kasperk R, et al. (2002) Recurrent inguinal hernia: disease of the collagen matrix? World J Surg 26: 401–408

    Article  PubMed  Google Scholar 

  62. Ajabnoor MA, Mokhtar AM, Rafee AA, Taha AM (1992) Defective collagen metabolism in Saudi patients with hernia. Ann Clin Biochem 29 (Pt 4): 430–436

    PubMed  Google Scholar 

  63. Jorgensen LN, Sorensen LT, Kallehave F, Schulze S, Gottrup F (2001) Increased collagen deposition in an uncomplicated surgical wound compared to a minimal subcutaneous test wound. Wound Repair Regen 9: 194–199

    Article  PubMed  CAS  Google Scholar 

  64. Ågren MS, Jorgensen LN, Andersen M, Viljanto J, Gottrup F (1998) Matrix metalloproteinase 9 level predicts optimal collagen deposition during early wound repair in humans. Br J Surg 85: 68–71

    Article  PubMed  Google Scholar 

  65. Peacock EE Jr (1975) Subcutaneous extraperitoneal repair of ventral hernias: a biological basis for fascial transplantation. Ann Surg 181: 722–727

    Article  PubMed  Google Scholar 

  66. Marks MG, Doillon C, Silver FH (1991) Effects of fibroblasts and basic fibroblast growth factor on facilitation of dermal wound healing by type I collagen matrices. J Biomed Mater Res 25: 683–696

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Surgery, Bispebjerg Hospital, Bakke 23, 2400, København, Denmark

    L. T. Sorensen

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  1. L. T. Sorensen
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  2. L. N. Jorgensen
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Editors and Affiliations

  1. Chirurgische Klinik, Universitätsklinikum Aachen, Pauwelsstraße 30, 52074, Aachen, Germany

    Volker Schumpelick

  2. Department of Surgery, Creighton University, 601 North 30th Street Suite 3740, Omaha, NE, 68131, USA

    Robert J. Fitzgibbons

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Sorensen, L.T., Jorgensen, L.N. (2007). Non-Surgical Risk Factors for Recurrence of Hernia. In: Schumpelick, V., Fitzgibbons, R.J. (eds) Recurrent Hernia. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-68988-1_5

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  • DOI: https://doi.org/10.1007/978-3-540-68988-1_5

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