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Exercise for Prevention of Bone Loss: The Role of Sports Medicine

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Non-Pharmacological Management of Osteoporosis

Abstract

Physical activity and especially physical exercise are considered as cornerstones of musculoskeletal health. Indeed, dedicated exercise protocols can affect all fracture parameters, i.e. fall risk, fall impact, and bone strength, and should thus be considered as optimum candidates for non-pharmacological fracture prevention. Some evidence for the general anti-fracture efficacy of exercise was provided by dedicated exercise trials and a corresponding meta-analysis, but the optimum strategy (if there is any) on how to prevent fractures in elderly subjects is still under discussion. Although some researchers postulate to focus more on falls than on osteoporosis to prevent fractures, the most promising and feasible exercise strategy is to select types of exercise that address both factors, falls, and osteoporosis. This approach, however, ought to consider the requirements and determining factors of each individual. That is, the need for fall prevention is higher for elderly subjects with several fall risk factors, while for early postmenopausal women with distinct bone loss, this topic is of lesser relevance. But even with careful adaptation of the exercise program to subjects’ changing bone, health, and fitness status, effectivity may still decrease over the time. This could specifically be the case where the limitations of higher age collide with the specification of the exercise program. In the Erlangen Fitness and Osteoporosis Prevention Study (EFOPS), the overall aim was to evaluate the effect of a multipurpose exercise program on clinical low-trauma fractures in postmenopausal women starting to exercise in their early postmenopausal years. In detail, we intended to answer the following research questions:

  1. 1.

    Can exercise reduce the risk of osteoporotic fractures in postmenopausal women?

  2. 2.

    Is there an optimal exercise program to increase or maintain bone mineral density?

  3. 3.

    Are there temporary limitations on the effectivity of exercise on bone?

  4. 4.

    Can exercise program that focuses on fracture reduction relevantly affect other risk factors with advancing age?

  5. 5.

    Are high-intensity anti-fracture exercise programs attractive and feasible?

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References

  1. Börjesson M, Hellenius ML, Jansson E, et al. Physical activity in the prevention and treatment of disease. Stockholm: Swedish Institute of Health; 2010.

    Google Scholar 

  2. Vuori I. Exercise and physical health: musculoskeletal health and functional capacities. Res Q Exerc Sport. 1995;66:276–85.

    Article  CAS  PubMed  Google Scholar 

  3. Gillespie LD, Robertson MC, Gillespie WJ, et al. Interventions for preventing falls in older people living in the community. Cochrane Database Syst Rev. 2012;9:CD007146.

    Google Scholar 

  4. Groen BE, Smulders E, de Kam D, et al. Martial arts fall training to prevent hip fractures in the elderly. Osteoporos Int. 2010;21:215–21.

    Article  CAS  PubMed  Google Scholar 

  5. Weerdesteyn V, Groen BE, van Swigchem R, et al. Martial arts fall techniques reduce hip impact forces in naive subjects after a brief period of training. J Electromyogr Kinesiol. 2008;18:235–42.

    Article  CAS  PubMed  Google Scholar 

  6. Marques EA, Mota J, Carvalho J. Exercise effects on bone mineral density in older adults: a meta-analysis of randomized controlled trials. Age. 2011;34:1493–515.

    Article  PubMed  PubMed Central  Google Scholar 

  7. Nikander R, Sievanen H, Heinonen A, et al. Targeted exercise against osteoporosis: a systematic review and meta-analysis for optimising bone strength throughout life. BMC Med. 2010;8:47.

    Article  PubMed  PubMed Central  Google Scholar 

  8. Sinaki M, Itoi E, Wahner HW, et al. Stronger back muscles reduce the incidence of vertebral fractures: a prospective 10 year follow-up of postmenopausal women. Bone. 2002;30:836–41.

    Article  CAS  PubMed  Google Scholar 

  9. Korpelainen R, Keinanen-Kiukaanniemi S, Heikkinen J, et al. Effects of impact exercise on bone mineral density in elderly women with low BMD: a population based randomized controlled 30-month intervention. Osteoporos Int. 2006;17:109–18.

    Article  PubMed  Google Scholar 

  10. Kemmler W, Haberle L, von Stengel S. Effects of exercise on fracture reduction in older adults: a systematic review and meta-analysis. Osteoporos Int. 2013;24:1937–50.

    Article  CAS  PubMed  Google Scholar 

  11. Jarvinen TL, Sievanen H, Khan KM, et al. Shifting the focus in fracture prevention from osteoporosis to falls. BMJ. 2008;336:124–6.

    Article  PubMed  PubMed Central  Google Scholar 

  12. Kemmler W, von Stengel S. Exercise and osteoporosis-related fractures: perspectives and recommendations of the sports and exercise scientist. Phys Sportsmed. 2011;39:142–57.

    Article  PubMed  Google Scholar 

  13. Kemmler W, Lauber D, Von Stengel S, et al. Developing maximum strength in older adults—a series of studies. In: Gießing J, Fröhlich M, Preuss P, editors. Current results of strength training research. Göttingen: Cuvillier Verlag; 2005. p. 114–33.

    Google Scholar 

  14. von Stengel S, Kemmler W, Lauber D, et al. Power training is more effective than strength training to maintain bone mineral density in postmenopausal woman. J Appl Physiol. 2005;99:181–8.

    Article  CAS  PubMed  Google Scholar 

  15. von Stengel S, Kemmler W, Kalender WA, et al. Differential effects of strength versus power training on bone mineral density in postmenopausal women: a 2-year longitudinal study. Br J Sports Med. 2007;41:649–55; discussion 55.

    Google Scholar 

  16. Mosley JR, Lanyon LE. Strain rate as a controlling influence on adaptive modeling in response to dynamic loading of the ulna in growing male rats. Bone. 1998;23:313–8.

    Article  CAS  PubMed  Google Scholar 

  17. Borg E, Kaijser L. A comparison between three rating scales for perceived exertion and two different work tests. Scand J Med Sci Sports. 2006;16:57–69.

    Article  CAS  PubMed  Google Scholar 

  18. Expert-Panel. Executive summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III). JAMA. 2001;285:2486–97.

    Article  Google Scholar 

  19. DVO. DVO-Leitlinien 2014 zur Prophylaxe, Diagnostik und Therapie der Osteoporose bei Männern ab dem 60. Lebensjahr und postmenopausalen Frauen. Stuttgart: Schattauer; 2014.

    Google Scholar 

  20. Kanis JA, McCloskey EV, Johansson H, et al. Development and use of FRAX in osteoporosis. Osteoporos Int. 2010;21(Suppl 2):S407–13.

    Article  PubMed  Google Scholar 

  21. Salamone LM, Dallal GE, Zantos D, et al. Contributions of vitamin D intake and seasonal sunlight exposure to plasma 25-hydroxyvitamin D concentration in elderly women. Am J Clin Nutr. 1994;59:80–6.

    CAS  PubMed  Google Scholar 

  22. Gillespie LD, Robertson MC, Gillespie WJ, et al. Interventions for preventing falls in older people living in the community. Cochrane Database Syst Rev. 2009;(2):CD007146.

    Google Scholar 

  23. Karinkanta S, Piirtola M, Sievanen H, et al. Physical therapy approaches to reduce fall and fracture risk among older adults. Nat Rev Endocrinol. 2010;6(7):396-407 (online first).

    Google Scholar 

  24. Cohen J. Statistical power analysis for the behavioral sciences. Hillsdale: Lawrence Earlbaum Associates; 1988.

    Google Scholar 

  25. Robertson MC, Devlin N, Gardner MM, et al. Effectiveness and economic evaluation of a nurse delivered home exercise programme to prevent falls. 1: Randomised controlled trial. BMJ. 2001;322:697–701.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  26. Robertson MC, Gardner MM, Devlin N, et al. Effectiveness and economic evaluation of a nurse delivered home exercise programme to prevent falls. 2: Controlled trial in multiple centres. BMJ. 2001;322:701–4.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  27. Jansen JP, Bergman GJ, Huels J, et al. The efficacy of bisphosphonates in the prevention of vertebral, hip, and nonvertebral-nonhip fractures in osteoporosis: a network meta-analysis. Semin Arthritis Rheum. 2011;40:275–84 e1–2.

    Google Scholar 

  28. Black DM, Delmas PD, Eastell R, et al. Once-yearly zoledronic acid for treatment of postmenopausal osteoporosis. N Engl J Med. 2007;356:1809–22.

    Article  CAS  PubMed  Google Scholar 

  29. McCloskey EV, Johansson H, Oden A, et al. Denosumab reduces the risk of osteoporotic fractures in postmenopausal women, particularly in those with moderate to high fracture risk as assessed with FRAX. J Bone Miner Res. 2012;27:1480–6.

    Article  CAS  PubMed  Google Scholar 

  30. Neer RM, Arnaud CD, Zanchetta JR. Effect of parathyroid hormone (1-34) on fractures and bone mineral density in postmenopausal women with osteoporosis. N Engl J Med. 2001;344:1434–41.

    Article  CAS  PubMed  Google Scholar 

  31. Kemmler W, von Stengel S. Exercise frequency, health risk factors, and diseases of the elderly. Arch Phys Med Rehabil. 2013;94:2046–53.

    Article  PubMed  Google Scholar 

  32. Kemmler W, von Stengel S. Dose-response effect of exercise frequency on bone mineral density in post-menopausal, osteopenic women. Scand J Med Sci Sports. 2014;24:526–34.

    Article  CAS  PubMed  Google Scholar 

  33. Rütten A, Abu-Omar K, Lampert T, et al. Körperliche Aktivität [Physical activity]. Report. Berlin: Statistisches Bundesamt; 2005.

    Google Scholar 

  34. ACSM. Progression models in resistance training for healthy adults. Med Sci Sports. 2002;34:364–80.

    Google Scholar 

  35. Baechle TR. Essentials of strength training and conditioning. Champaign: Human Kinetics; 1994.

    Google Scholar 

  36. Bompa TO. Periodization. Theorie and methodology of training. Champaign: Human Kinetics; 1999.

    Google Scholar 

  37. Howe TE, Shea B, Dawson LJ, et al. Exercise for preventing and treating osteoporosis in postmenopausal women. Cochrane Database Syst Rev. 2011;(7):CD000333.

    Google Scholar 

  38. Sherrington C, Whitney JC, Lord SR, et al. Effective exercise for the prevention of falls: a systematic review and meta-analysis. J Am Geriatr Soc. 2008;56:2234–43.

    Article  PubMed  Google Scholar 

  39. Wagner P. Aussteigen oder Dabeibleiben? [dissertation]. Darmstadt: Technical University Darmstadt; 2000.

    Google Scholar 

  40. Kemmler W, Bebenek M, von Stengel S, et al. Effect of block-periodized exercise training on bone and coronary heart disease risk factors in early post-menopausal women: a randomized controlled study. Scand J Med Sci Sports. 2013;23:121–9.

    Article  CAS  PubMed  Google Scholar 

  41. Saxon LK, Robling AG, Alam IM, et al. Mechanosensitivity of the rat skeleton decreases after a long period of loading, but is improved with time off. Bone. 2005;36:454–64.

    Article  CAS  PubMed  Google Scholar 

  42. Kemmler W, Lauber D, Weineck J, et al. Benefits of 2 years of intense exercise on bone density, physical fitness, and blood lipids in early postmenopausal osteopenic women: results of the Erlangen Fitness Osteoporosis Prevention Study (EFOPS). Arch Intern Med. 2004;164:1084–91.

    Article  PubMed  Google Scholar 

  43. Tesch-Römer C, Engstler H, Wurm S. Altwerden in Deutschland. Sozialer Wandel und individuelle Entwicklung in der zweiten Lebenshälfte. Wiesbaden: VS-Verlag für Sozialwissenschaften; 2006.

    Google Scholar 

  44. Löwel H. Koronare Herzkrankheit und akuter Myokardinfarkt. Berlin: Robert-Koch-Institut; 2006.

    Google Scholar 

  45. Roger VL, Go AS, Lloyd-Jones DM, et al. Executive summary: heart disease and stroke statistics—2012 update: a report from the American Heart Association. Circulation. 2012;125:188–97.

    Article  PubMed  Google Scholar 

  46. Chodzko-Zajko WJ, Proctor DN, Fiatarone Singh MA, et al. American College of Sports Medicine position stand. Exercise and physical activity for older adults. Med Sci Sports Exerc. 2009;41:1510–30.

    Article  PubMed  Google Scholar 

  47. Pedersen BK, Saltin B. Evidence for prescribing exercise as a therapy in chronic disease. Scand J Med Sci Sports. 2006;16:3–63.

    Article  PubMed  Google Scholar 

  48. Gibala MJ, Little JP, Macdonald MJ, et al. Physiological adaptations to low-volume, high-intensity interval training in health and disease. J Physiol. 2012;590:1077–84.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  49. Guiraud T, Nigam A, Gremeaux V, et al. High-intensity interval training in cardiac rehabilitation. Sports Med. 2012;42:587–605.

    Article  PubMed  Google Scholar 

  50. Hansen D, Dendale P, van Loon LJ, et al. The impact of training modalities on the clinical benefits of exercise intervention in patients with cardiovascular disease risk or type 2 diabetes mellitus. Sports Med. 2010;40:921–40.

    Article  PubMed  Google Scholar 

  51. Haykowsky MJ, Timmons MP, Kruger C, et al. Meta-analysis of aerobic interval training on exercise capacity and systolic function in patients with heart failure and reduced ejection fractions. Am J Cardiol. 2013;111:1466–9.

    Article  PubMed  Google Scholar 

  52. Strasser B, Siebert U, Schobersberger W. Resistance training in the treatment of the metabolic syndrome: a systematic review and meta-analysis of the effect of resistance training on metabolic clustering in patients with abnormal glucose metabolism. Sports Med. 2010;40:397–415.

    Article  PubMed  Google Scholar 

  53. Kemmler W, von Stengel S, Weineck J, et al. Exercise effects on menopausal risk factors of early postmenopausal women: 3-yr Erlangen fitness osteoporosis prevention study results. Med Sci Sports Exerc. 2005;37:194–203.

    Article  PubMed  Google Scholar 

  54. Alberti KG, Zimmet P, Shaw J. Metabolic syndrome—a new world-wide definition. A Consensus Statement from the International Diabetes Federation. Diabet Med. 2006;23:469–80.

    Article  CAS  PubMed  Google Scholar 

  55. Johnson JL, Slentz CA, Houmard JA, et al. Exercise training amount and intensity effects on metabolic syndrome (from studies of a targeted risk reduction intervention through defined exercise). Am J Cardiol. 2007;100:1759–66.

    Article  PubMed  PubMed Central  Google Scholar 

  56. Turner CH. Exercise as a therapy for osteoporosis: the drunk and the street lamp, revisited. Bone. 1998;23:83–5.

    Article  CAS  PubMed  Google Scholar 

  57. Vuori IM. Dose-response of physical activity and low back pain, osteoarthritis, and osteoporosis. Med Sci Sports Exerc. 2001;33:S551–S86.

    Article  CAS  PubMed  Google Scholar 

  58. Kemmler W, Bebenek M, Kohl M, et al. Long-term exercise effects on health parameters in postmenopausal females. Final Results of the Erlangen Fitness and Osteoporosis Prevention Study (EFOPS). Menopause 2017;24:45–51.

    Google Scholar 

  59. Raspe H, Kohlmann T. Rückenschmerzen—eine Epidemie unserer Tage. Dtsch Arztebl. 1993;90:B2165–9.

    Google Scholar 

  60. Fukumoto Y, Tateuchi H, Ikezoe T, et al. Effects of high-velocity resistance training on muscle function, muscle properties, and physical performance in individuals with hip osteoarthritis: a randomized controlled trial. Clin Rehabil. 2014;28:48–58.

    Article  PubMed  Google Scholar 

  61. Liu CJ, Latham NK. Progressive resistance strength training for improving physical function in older adults. Cochrane Database Syst Rev. 2009;(3):CD002759.

    Google Scholar 

  62. Mangione KK, Miller AH, Naughton IV. Cochrane review: improving physical function and performance with progressive resistance strength training in older adults. Phys Ther. 2010;90:1711–5.

    Article  PubMed  Google Scholar 

  63. Wolff I, van Croonenborg JJ, Kemper HC, et al. The effect of exercise training programs on bone mass: a meta-analysis of published controlled trials in pre- and postmenopausal women. Osteoporos Int. 1999;9:1–12.

    Article  CAS  PubMed  Google Scholar 

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Kemmler, W., von Stengel, S. (2017). Exercise for Prevention of Bone Loss: The Role of Sports Medicine. In: Sinaki, M., Pfeifer, M. (eds) Non-Pharmacological Management of Osteoporosis. Springer, Cham. https://doi.org/10.1007/978-3-319-54016-0_6

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  • DOI: https://doi.org/10.1007/978-3-319-54016-0_6

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