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Scars and Stress

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Stress and Skin Disorders

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Abstract

Scars are the result of the wound healing process in the skin and other body tissues. Even though they are part of the normal process of healing, they can sometimes be bothersome. Inadequate scars can lead to loss of function, restriction of growth, restriction of movement (particularly because of contractures over joints), poor aesthetics, and adverse psychological effects. Although there are multitudes of options for the treatment of scars, prevention is still the best option. In this chapter we aim to show evidence that stress can affect wound healing producing unaesthetic scars such as keloids, as well as suggest possible solutions.

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Article 16 November 2023

References

  1. Aberg KM, Radek KA, Choi EH, Kim DK, Demerjian M, Hupe M, Kerbleski J, Gallo RL, Ganz T, Mauro T, Feingold KR, Elias PM. Psychological stress downregulates epidermal antimicrobial peptide expression and increases severity of cutaneous infections in mice. J Clin Invest. 2007;117(11):3339–49.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  2. Altemus M, Rao B, Dhabhar FS, Ding W, Granstein RD. Stress-induced changes in skin barrier function in healthy women. J Invest Dermatol. 2001;117(2):309–17.

    Article  CAS  PubMed  Google Scholar 

  3. Burns V, Drayson M, Ring C, Carroll D. Perceived stress and psychological well-being are associated with antibody status after meningitis C conjugate vaccination. Psychosom Med. 2002;64(6):963–70.

    CAS  PubMed  Google Scholar 

  4. Carvalho B, Ballin AC, Berger R, Ribeiro TB, Cavichiolo J, Ballin CR, Mocellin M. Treatment of retroauricular keloids: revision of cases treated at the ENT Service of HC/UFPR. Intl Arch Otorhinolaryngol. 2012;16(2):195–200.

    Google Scholar 

  5. Chen Y, Lyga J. Brain-skin connections: stress, inflammation and skin aging. Inflamm Allergy Drug Targets. 2014;13(3):177–90.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  6. Cole-King A, Harding KG. Psychological factors and delayed healing in chronic wounds. Psychosom Med. 2001;63(2):216–20.

    Article  CAS  PubMed  Google Scholar 

  7. Furtado F, Hochman B, Farber PL, Muller MC, Hayashi LF, Ferreira LM. Psychological stress as a risk factor for postoperative keloid recurrence. J Pshychosom Res. 2012;72:282–7.

    Article  Google Scholar 

  8. Furtado F, Hochman B, Ferrara SF, Dini GM, Nunes JM, Juliano Y, Ferreira LM. What factors affect the quality of life of patients with keloid? Rev Assoc Med Bras. 2009;55(6):700–4.

    Article  PubMed  Google Scholar 

  9. Garg A, Chren MM, Sands LP, Matsui MS, Marenus KD, Feingold KR, Elias PM. Psychological stress perturbs epidermal permeability barrier homeostasis: implications for the pathogenesis of stress-associated skin disorders. Arch Dermatol. 2001;137(1):53–9.

    Article  CAS  PubMed  Google Scholar 

  10. Gauglitz GG, Korting HC, Pavicic T, Ruzicka T, Jeschke M. Hypertrophic scarring and keloids: pathomechanisms and current and emerging treatment strategies. Mol Med. 2011;17(1–2):113–25.

    CAS  PubMed  Google Scholar 

  11. Gouin J-P, Kiecolt-Glaser JK. The impact of psychological stress on wound healing: methods and mechanisms. Immunol Allergy Clin North Am. 2011;31(1):81–93.

    Article  PubMed  PubMed Central  Google Scholar 

  12. Hochman B, Farkas CB, Isoldi FC, Ferrara SF, Furtado F, Ferreira LM. Distribuição de queloide e cicatriz hipertrofica Segundo fototipos de pele de Fitzpatrick. Rev Bras Cir Plast. 2012;27(2):185–9.

    Article  Google Scholar 

  13. Hochman B, Furtado F, Isoldi FC, Nishioka MA, Ferreira LM. Psychological stress and skin wound healing: new highlights. In: Psychology of stress. New York: Nova Science Publishers, Inc; 2013.

    Google Scholar 

  14. Hochman B, Ishizuka CK, Ferreira LM, Oliveira LQ, Locali RF. Disfunções cicatriciais hiperproliferativas: Cicatrizes hipertróficas. Estima. 2004;2(3):32–9.

    Google Scholar 

  15. Hochman B, Locali RF, Oliveira LQR, Ferreira LM. Disfunções cicatriciais hiperproliferativas: Quelóide. Estima. 2004;2(4):33–9.

    Google Scholar 

  16. Kiecolt-Glaser JK, Marucha PT, Malarkey WB, Mercado AM, Glaser R. Slowing of wound healing by psychological stress. Lancet. 1995;346(8984):1194–6.

    Article  CAS  PubMed  Google Scholar 

  17. Liu A, Moy RL, Ozog DM. Current methods employed in the prevention and minimization of surgical scars. Dermatol Surg. 2011;37(12):1740–6.

    Article  CAS  PubMed  Google Scholar 

  18. Muizuddin N, Matsui MS, Marenus KD, Maes DH. Impact of stress of marital dissolution on skin barrier recovery: tape stripping and measurement of trans-epidermal water loss (TEWL). Skin Res Technol. 2003;9(1):34–8.

    Article  Google Scholar 

  19. Phillips AC. Perceived stress. In: Encyclopedia of behavioral medicine. New York: Springer; 2007. p. 1453–4.

    Google Scholar 

  20. Slominski A. A nervous breakdown in the skin: stress and the epidermal barrier. J Clin Invest. 2007;117:3166–9.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  21. Son D, Harijan A. Overview of surgical scar prevention and management. J Korean Med Sci. 2014;29:751–7.

    Article  PubMed  PubMed Central  Google Scholar 

  22. The American Society for Aesthetic Plastic Surgery. Statistics released by The American Society for Aesthetic Plastic Surgery, Issued 2015. Available at: www.surgery.org/media/statistics Accessed 11 May 2016.

  23. Thomas JR, Dizon TK. Preoperative evaluation of the aging neck patient. Facial Plast Surg Clin North Am. 2014;22(2):171–6.

    Article  PubMed  Google Scholar 

  24. U.S Census Bureau. An aging nation: the older population in the United States. Issued May 2014. Available at: http://www.census.gov/prod/2014pubs/p25-1140.pdf. Accessed 11 May 2016.

  25. Vieira MH, Amini S, Valins W, Berman B. Innovative therapies in the treatment of keloids and hypertrophic scars. J Clin Aesthet Dermatol. 2010;3(5):20–6.

    Google Scholar 

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Author information

Authors and Affiliations

  1. CEFOR (Center of the Face and Otolaryngology), 369 Bruno Filgueira Street, 80240-220, Curitiba, PR, Brazil

    Annelyse Cristine Ballin MD

  2. Faculty of Medicine of Santa Casa of São Paulo, São Paulo, SP, Brazil

    Annelyse Cristine Ballin MD

  3. Otolaryngology Department, Federal University of Parana, Curitiba, PR, Brazil

    Bettina Carvalho MD

  4. Centro Studi per la Ricerca Multidisciplinare e Rigenerativa, Università Degli Studi “G. Marconi”, Rome, Italy

    Katlein França MD, PhD

  5. Department of Dermatology and Cutaneous Surgery, Department of Psychiatry and Behavioral Sciences, Institute for Bioethics and Health Policy, University of Miami Miller School of Medicine, Miami, FL, USA

    Katlein França MD, PhD

  6. Department of Otolaryngology, University of São Paulo, São Paulo, SP, Brazil

    Flavia Lira Diniz MD

Authors
  1. Annelyse Cristine Ballin MD
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  2. Bettina Carvalho MD
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  3. Katlein França MD, PhD
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  4. Flavia Lira Diniz MD
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Corresponding author

Correspondence to Annelyse Cristine Ballin MD .

Editor information

Editors and Affiliations

  1. Centro Studi per la Ricerca Multidisciplinare e Rigenerativa Department of Dermatology, Università degli Studi Guglielmo Marconi, Rome, Italy

    Katlein França

  2. Department of Psychiatry, Central Michigan University College of Medicine, Saginaw, Michigan, USA

    Mohammad Jafferany

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© 2017 Springer International Publishing Switzerland

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Ballin, A.C., Carvalho, B., França, K., Diniz, F.L. (2017). Scars and Stress. In: França, K., Jafferany, M. (eds) Stress and Skin Disorders. Springer, Cham. https://doi.org/10.1007/978-3-319-46352-0_7

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  • DOI: https://doi.org/10.1007/978-3-319-46352-0_7

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  • Publisher Name: Springer, Cham

  • Print ISBN: 978-3-319-46351-3

  • Online ISBN: 978-3-319-46352-0

  • eBook Packages: MedicineMedicine (R0)

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