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Current State of Metal-Based Drugs for the Efficient Therapy of Lung Cancers and Lung Metastases

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Lung Cancer and Personalized Medicine

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 893))

Abstract

Lung cancer is the second most common cancer in both men and women and thus a leading cause of cancer-related deaths worldwide. New efficient treatments especially for its advanced stages and metastases are desperately needed, particularly with regard to overcoming the resistance which thwarts the efficacy of most clinically established drugs such as the platinum complexes. Glimpses of hope are new metal-based drugs that have emerged over the past decade which displayed efficacy in patients with platinum-resistant tumors and metastases. This chapter provides an overview of the latest developments of such metal-based drugs against lung cancer.

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Authors and Affiliations

  1. Organic Chemistry Laboratory, University of Bayreuth, Universitätsstr. 30, 95447, Bayreuth, Germany

    Bernhard Biersack & Rainer Schobert

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  1. Bernhard Biersack
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  2. Rainer Schobert
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Correspondence to Bernhard Biersack .

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Editors and Affiliations

  1. Wayne State University, Karmanos Cancer Institute, Detroit, Michigan, USA

    Aamir Ahmad

  2. Wayne State University, Karmanos Cancer Institute, Detroit, Michigan, USA

    Shirish Gadgeel

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Biersack, B., Schobert, R. (2016). Current State of Metal-Based Drugs for the Efficient Therapy of Lung Cancers and Lung Metastases. In: Ahmad, A., Gadgeel, S. (eds) Lung Cancer and Personalized Medicine. Advances in Experimental Medicine and Biology, vol 893. Springer, Cham. https://doi.org/10.1007/978-3-319-24223-1_11

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