Abstract
Urinary function consists of a “storage” phase, in which tonic activation of urethral sphincter muscle occurs and bladder detrusor muscle is inhibited, and a “voiding” phase, in which detrusor activation and sphincter relaxation favor passing of urine. Both are under voluntary and involuntary neural control. Disorders of neural control of urinary function are also known as “neurogenic bladder” or “neurogenic lower urinary tract dysfunction.” Four main clinical pathological patterns can be distinguished at examination, with different therapeutic implications [27]:
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1.
Bladder detrusor overactivity: bladder storage capacity is reduced, but no or only low urine post-void volume occurs.
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2.
Detrusor sphincter dyssynergia: bladder storage capacity is reduced. Lack of coordination between bladder detrusor activation and urethral sphincter relaxation additionally induces post-void residual urine.
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3.
Hypoactive bladder: bladder capacity is increased. Insufficient detrusor activation leads to high post-void residual urine.
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4.
Hypoactive sphincter: bladder storage capacity is reduced, with no post-void residual urine.
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Acknowledgments
JNP undertook this work at UCLH/UCL Institute of Neurology and is supported in part by funding from the United Kingdom’s Department of Health NIHR Biomedical Research Centres funding scheme.
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Fanciulli, A., Kiss, G., Eschlböck, S., Wenning, G.K., Panicker, J.N. (2017). Bladder and Sexual Dysfunction. In: Struhal, W., Lahrmann, H., Fanciulli, A., Wenning, G. (eds) Bedside Approach to Autonomic Disorders. Springer, Cham. https://doi.org/10.1007/978-3-319-05143-7_5
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