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Bendamustine

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Extravasation of Cytotoxic Agents

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Abstract

1. Stop injection/infusion immediately

2. Get extravasation kit

3. Put on (sterile) gloves

4. Replace infusion lead or syringe with 5 ml disposable syringe and aspirate slowly as much as possible of the extravasated drug; Cave! do not exert pressure on extravasation area

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Original articles

  1. Ruffert K, Jahn H, Syrbe G, et al: Cytostasan® (Bendamustin) in der Alternativtherapie maligner Non-Hodgkin-Lymphome – -Cytostasan (bendamustin) as an alternative therapeutic approach to treat malignant non-Hodgkin’s lymphoma. Z Klin Med 44: -671–674, 1989.

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Secondary literature

  1. Gain M, Melzer S, Meyer-Jürshof A, et al: Bendamustin: Behandlung von Paravasaten. In: Gain M, et al (eds) ADKA-Zytostatika-Handbuch, Pharmazeutisch-wissenschaftliche Monographien. Verlag Heiner Biller, vol 4: 24, 2000.

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  2. Sauer H: Substanzprofile, Zytostatika, Hormone, Zytokine: Bendamustin. In: Schmoll HJ, Höffken K, Possinger K (eds) Kompendium Internistische Onkologie. Standards in Diagnostik und Therapie. Springer, Vol 1, 3rd edition: 736–737, 1999.

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  3. Summary of product characteristics Ribomustin® (Germany), -ribosepharm, September 2003.

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  4. Information for hospital pharmacists Ribomustin® (Germany), -ribosepharm, October 1998.

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  5. Krämer I, Stützle M: Zytostatika-Paravasation – Wie ist vorzugehen? Krankenhauspharmazie 23: 261–268, 2002.

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  6. Jordan K, Grothe W, Schmoll HJ: Paravasation von Zytostatika: Prävention und Therapie. Dtsch Med Wochenschr 130: 33–37, 2005.

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Author information

Authors and Affiliations

  1. CRETA – Cancer Research & Trial Agency GmbH, Bad Sauerbrunn, Österreich

    Ines Mader MD

  2. Krankenhaus und Geriatriezentrum, SMZ Floridsdorf, Wien, Österreich

    Mag. pharm. Patrizia Fürst-Weger

  3. Klinische Abteilung für Onkologie, Univ.-Klinik für Innere Medizin I, Wien, Österreich

    Univ.-Prof. Dr. Robert Mader

  4. Anstaltsapotheke, Landeskrankenhaus – Universitätskliniken Innsbruck, Innsbruck, Österreich

    Mag. pharm. Dr. Elisabeth Nogler-Semenitz

  5. Apotheke LKH-Univ.-Klinikum Graz, Graz, Österreich

    Mag. pharm. Sabine Wassertheurer

Authors
  1. Ines Mader MD
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  2. Mag. pharm. Patrizia Fürst-Weger
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  3. Univ.-Prof. Dr. Robert Mader
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  4. Mag. pharm. Dr. Elisabeth Nogler-Semenitz
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  5. Mag. pharm. Sabine Wassertheurer
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© 2010 Springer-Verlag/Wien

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Mader, I., Fürst-Weger, P., Mader, R., Nogler-Semenitz, E., Wassertheurer, S. (2010). Bendamustine. In: Extravasation of Cytotoxic Agents. Springer, Vienna. https://doi.org/10.1007/978-3-211-88893-3_14

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  • DOI: https://doi.org/10.1007/978-3-211-88893-3_14

  • Publisher Name: Springer, Vienna

  • Print ISBN: 978-3-211-88889-6

  • Online ISBN: 978-3-211-88893-3

  • eBook Packages: MedicineMedicine (R0)

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