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Life with Epidermolysis Bullosa (EB)

Abstract

The term epidermolysis bullosa (EB) hereditaria comprises a group of genetically and clinically heterogeneous diseases which are characterized by the formation of blisters and erosions on skin and mucous membranes following minor traction or trauma (i.e. “mechano-bullous diseases”). The name EB was first used by Koebner in 1886 [6] although cases consistent with this diagnosis were described earlier by others [4]. Our current nomenclature reflects the ongoing efforts of many clinicians and researchers throughout the twentieth century whose published reports on new clinical variants and diagnostically useful laboratory findings have allowed EB patients to be distinguished phenotypically, ultrastructurally, antigenically, and now most recently, molecularly.

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Authors and Affiliations

  1. Universitätsklinik für Dermatologie, Paracelsus Medizinische Privatuniversität Salzburg, Salzburg, Austria

    Dr. Christoph M. Lanschuetzer, Dr. Martin Laimer, Dr. Gabriela Pohla-Gubo, Dr. Elke Nischler, Univ.-Prof. Dr. Helmut Hintner, Alfred Klausegger & Univ.-Doz. Dr. Johann Bauer

  2. Department of Medicine (Dermatology) & Pediatrics, Vanderbilt University School of Medicine, USA

    Prof. Jo-David Fine (Head)

  3. National (USA) Epidermolysis Bullosa Registry, Nashville, TN, USA

    Prof. Jo-David Fine (Head)

  4. St. John’s Institute of Dermatology, King’s College London School of Medicine St. Thomas’ Hospital, London, UK

    Professor Robin A. J. Eady & Dr. Hiva Fassihi

  5. Genetic Skin Disease Group, St. John’s Institute of Dermatology King’s College London School of Medicine, London, UK

    Prof. John McGrath

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  1. Division of Dermatology, Department of Medicine, Vanderbilt University School of Medicine, and National EB Registry, Nashville, Tennessee, USA

    Jo-David Fine

  2. Universitätsklinik für Dermatologie, Paracelsus Medizinische Privatuniversität Salzburg, Salzburg, Österreich

    Helmut Hintner

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Lanschuetzer, C.M. et al. (2009). General Aspects. In: Fine, JD., Hintner, H. (eds) Life with Epidermolysis Bullosa (EB). Springer, Vienna. https://doi.org/10.1007/978-3-211-79271-1_1

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