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Special Considerations for Peritoneal Washings

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The International System for Serous Fluid Cytopathology

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Abstract

Peritoneal washings (PW) can present frustrating dilemmas for the cytologist due to the prevalence, predominately in women, of benign proliferative processes of Müllerian, mesonephric, and mesothelial origin that may occur. In most instances, peritoneal washings or lavage are performed to screen for the presence of tumor cells in the peritoneal cavity and are performed in association with a surgical procedure. The goal of this assessment is not a primary cytologic diagnosis, but to confirm the presence or absence of tumor cells at that site, which makes comparison with the surgical specimen paramount. This chapter outlines an approach to these specimens, discusses commonly and uncommonly encountered entities along with their differential diagnoses and immunoprofiles, and provides numerous sample reports.

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Authors and Affiliations

  1. Departments of Pathology and Oncology, The John Hopkins University of School of Medicine, Baltimore, MD, USA

    Christopher VandenBussche

  2. Gynecology, Breast and Cytopathology, Joint Pathology Center, Silver Spring, MD, USA

    Barbara Crothers

  3. Department of Obstetrics and Gynecology, The Johns Hopkins Hospital, The Johns Hopkins University, Baltimore, MD, USA

    Amanda Fader

  4. Department of Obstetrics and Gynecology, Walter Reed National Military Medical Center, Bethesda, MD, USA

    Amanda Jackson

  5. Department of Pathology, The Ohio State University, Columbus, OH, USA

    Zaibo Li

  6. Magee Women’s Hospital, University of Pittsburgh Medical Center, Pittsburgh, PA, USA

    Chengquan Zhao

Authors
  1. Christopher VandenBussche
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  2. Barbara Crothers
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  3. Amanda Fader
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  4. Amanda Jackson
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  5. Zaibo Li
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  6. Chengquan Zhao
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Corresponding author

Correspondence to Christopher VandenBussche .

Editor information

Editors and Affiliations

  1. Cellular Pathology, Guy’s and St. Thomas’ NHS Foundation Trust, London, UK

    Ashish Chandra

  2. Gynecology, Breast and Cytopathology Joint Pathology Center, Silver Spring, MD, USA

    Barbara Crothers

  3. University of Wisconsin School of Medicine and Public Health, Department of Pathology and Laboratory Medicine and Wisconsin State Laboratory of Hygiene, Madison, WI, USA

    Daniel Kurtycz

  4. Department of Pathology, Medical Faculty of Porto University and Unit of Molecular Pathology, Institute of Molecular Pathology and Immunology Porto University, Porto, Portugal

    Fernando Schmitt

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VandenBussche, C., Crothers, B., Fader, A., Jackson, A., Li, Z., Zhao, C. (2020). Special Considerations for Peritoneal Washings. In: Chandra, A., Crothers, B., Kurtycz, D., Schmitt, F. (eds) The International System for Serous Fluid Cytopathology. Springer, Cham. https://doi.org/10.1007/978-3-030-53908-5_9

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