Skip to main content

An in-Depth Look at the Non Motor Symptom Scale

  • Chapter
  • First Online:
Handbook of Non-Motor Symptoms in Parkinson's Disease

Abstract

To provide a fast and reliable tool to measure the whole burden of non-motor symptoms in Parkinson’s disease The Non-Motor Symptoms Scale (NMSS) was developed in 2006 to provide clinicians with an instrument for assessment of non-motor symptoms (NMSs) in patients with Parkinson’s disease (PD) [1]. This validated instrument categorizes NMSs into 30 questions in nine domains. The scale estimates the impact of NMSs by weighing each symptom by frequency and severity, thus capturing their global burden for patients.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Chaudhuri KR, Martinez-Martin P, Brown RG, et al. The metric properties of a novel non-motor symptoms scale for Parkinson’s disease: Results from an international pilot study. Mov Disord 2007;22:1901-1911.

    Google Scholar 

  2. Chaudhuri KR, Prieto-Jurcynska C, Naidu Y, et al. The Nondeclaration of Nonmotor Symptoms of Parkinson’s Disease to Health Care Professionals: An International Study Using the Nonmotor Symptoms Questionnaire. Mov Disord 2010;25:704-709.

    Google Scholar 

  3. Shulman LM, Taback RL, Rabinstein AA, Weiner WJ. Non-recognition of depression and other nonmotor symptoms in Parkinson’s disease. Parkinsonism Relat Disord 2002;8:193-197.

    Google Scholar 

  4. Schrag A, Jahanshahi M, Quinn N. What contributes to quality of life in patients with Parkinson’s disease? J Neurol Neurosurg Psychiatry 2000;69:308-312.

    Google Scholar 

  5. Herlofson K, Larsen JP. The influence of fatigue on health-related quality of life in patients with Parkinson’s disease. Acta Neurol Scand 2003;107:1-6.

    Google Scholar 

  6. Martinez-Martin P, Catalan MJ, Benito-Leon J, et al. Impact of fatigue in Parkinson’s disease: the Fatigue Impact Scale for Daily Use (D-FIS). Qual Life Res 2006;15:597-606.

    Google Scholar 

  7. Marras C, McDermott MP, Rochon PA, Tanner CM, Naglie G, Lang AE. Predictors of deterioration in health-related quality of life in Parkinson’s disease: results from the DATATOP trial. Mov Disord 2008;23:653-659.

    Google Scholar 

  8. Rahman S, Griffin HJ, Quinn NP, Jahanshahi M. Quality of life in Parkinson’s disease: the relative importance of the symptoms. Mov Disord 2008;23:1428-1434.

    Google Scholar 

  9. Barone P, Antonini A, Colosimo C, et al. The PRIA MO study: A multicenter assessment of nonmotor symptoms and their impact on quality of life in Parkinson’s disease. Mov Disord 2009;24:1641-1649.

    Google Scholar 

  10. Qin Z, Zhang L, Sun F, et al. Health related quality of life in early Parkinson’s disease: impact of motor and non-motor symptoms, results from Chinese levodopa exposed cohort. Parkinsonism Relat Disord 2009;15:767-771.

    Google Scholar 

  11. Martinez-Martin P, Rodriguez-Blazquez C, Kurtis MM, et al. The Impact of Non Motor Symptoms on Health-Related Quality of Life of Patients with Parkinson’s Disease. Mov Disord 2011; 26:399-406.

    Google Scholar 

  12. Chaudhuri KR, Schapira AHV, Martinez-Martin P, et al. Can we improve the holistic assessment of Parkinson’s disease? The development of a non-motor symptom questionnaire and scale for Parkinson’s disease. Adv Clin Neurosci Rehabil 2004;4:20-25.

    Google Scholar 

  13. Chaudhuri KR, Yates L, Martinez-Martin P. The non-motor symptom complex of parkinson’s disease: a comprehensive assessment is essential. Curr Neurol Neurosci Rep 2005;5:275.

    Google Scholar 

  14. Chaudhuri KR, Martinez-Martin P. Quantitation of non-motor symptoms in Parkinson’s disease. Eur J Neurol 2008;15(suppl 2):2-7.

    Google Scholar 

  15. Martinez-Martin P, Rodriguez-Blazquez C, Abe K, et al. International study on the psychometric attributes of the Non-Motor Symptoms Scale in Parkinson disease. Neurology 2009;73:1584-1591.

    Google Scholar 

  16. Wang G, Hong Z, Cheng Q, et al. Validation of the Chinese non-motor symptoms scale for Parkinson’s disease: results from a Chinese pilot study. Clin Neurol Neurosurg 2009;111:523-526.

    Google Scholar 

  17. Storch A, Odin P, Trender-Gerhard I, et al. Non-motor Symptoms Questionnaire and Scale for Parkinson’s disease: Cross-cultural adaptation into the German language. Nervenarzt 2010;980-985.

    Google Scholar 

  18. Soh SE, Morris ME, McGinley JL. Determinants of health-related quality of life in Parkinson’s disease: A systematic review. Parkinsonism Relat Disord 2011;17:1-9.

    Google Scholar 

  19. Martinez-Martin P, Schapira AH, Stocchi F, et al. Prevalence of nonmotor symptoms in Parkinson’s disease in an international setting; study using nonmotor symptoms questionnaire in 545 patients. Mov Disord 2007;22:1623-1629.

    Google Scholar 

  20. Honig H, Antonini A, Martinez-Martin P, et al. Intrajejunal levodopa infusion in Parkinson’s disease: a pilot multicenter study of effects on nonmotor symptoms and quality of life. Mov Disord 2009;24:1468-1474.

    Google Scholar 

  21. Evatt ML, Chaudhuri KR, Chour KL, et al. Dysautonomia rating scales in Parkinson’s disease: sialorrhea, dysphagia, and constipation – critique and recommendations by movement disorders task force on rating scales for Parkinson’s disease. Mov Disord 2009;24:635-646.

    Google Scholar 

  22. Simkin S, Chaudhuri KR, Selway N. Subthalmic nucleus (STN) deep brain stimulation (DBS) and the non-motor symptom scale (NMSS) in Parkinson’s disease (PD). Mov Disord 2006;21:S685.

    Google Scholar 

  23. Kim HJ, Park SY, Cho YJ, et al. Nonmotor symptoms in de novo Parkinson disease before and after dopaminergic treatment. J Neurol Sci 2009;287:200-204.

    Google Scholar 

  24. Braak H, Del Tredici K, Rub U, De Vos RA, Jansen Steur EN, Braak E. Staging of brain pathology related to sporadic Parkinson’s disease. Neurobiol Aging 2003;24:197-211.

    Google Scholar 

  25. Tolosa E, Compta Y, Gaig C. The premotor phase of Parkinson’s disease. Parkinsonism Relat Disord 2007;13:S2-S7.

    Google Scholar 

  26. Parkinson Study Group. Dopamine transporter brain imaging to assess the effects of pramipexole vs levodopa on Parkinson disease progression. JAMA 2002;287:1653-1661.

    Google Scholar 

  27. Parkinson Study Group. A controlled, randomized, delayed-start study of rasagiline in early Parkinson disease. Arch Neurol 2004;61:561-566.

    Google Scholar 

  28. Whone AL, Watts RL, Stoessl AJ, et al. Slower progression of Parkinson’s disease with ropinirole versus levodopa: The REAL-PET study. Ann Neurol 2003;54:93-101.

    Google Scholar 

  29. Olanow CW, Rascol O, Hauser RE, et al. A double-blind, delayed-start trial of rasagiline in Parkinson’s disease. N Engl J Med 2009;361:1268-1278.

    Google Scholar 

  30. De La Fuente-Fernandez R, Schulzer M, Mak E, Sossi V. Trials of neuroprotective therapies for Parkinson’s disease: Problems and limitations. Parkinsonism Relat Disord 2010;16:365-369.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 2011 Springer Healthcare, a part of Springer Science+Business Media

About this chapter

Cite this chapter

Kurtis, M., Logishetty, K., Martinez-Martin, P. (2011). An in-Depth Look at the Non Motor Symptom Scale. In: Handbook of Non-Motor Symptoms in Parkinson's Disease. Springer Healthcare, Heidelberg. https://doi.org/10.1007/978-1-908517-60-9_4

Download citation

  • DOI: https://doi.org/10.1007/978-1-908517-60-9_4

  • Published:

  • Publisher Name: Springer Healthcare, Heidelberg

  • Print ISBN: 978-1-907673-23-8

  • Online ISBN: 978-1-908517-60-9

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics