Skip to main content

Pathogenesis of Diseases Caused by Viruses of the Bunyavirus Genus

  • Chapter
The Bunyaviridae

Part of the book series: The Viruses ((VIRS))

Abstract

The Bunyavirus genus of the family Bunyaviridae is named after Bunyamwera virus (Smithburn et al., 1946), and includes over 150 individual viruses classified in several serogroups. In addition to their serological relationship, members of the genus have been grouped together because of similar molecular features (Bishop and Shope, 1979; Bishop et al., 1980; Gonzalez-Scarano and Nathanson, 1995; see Chapters 1 and 2 in this volume). Almost all of the viruses in the Bunyavirus genus can be transmitted by mosquitoes to a large number of vertebrate hosts. From the standpoint of human infections, the viruses in the California serogroup are the most relevant, as they have been associated with influenza-like illnesses in central Europe and are an important cause of encephalitis in the midwestern United States. However, other members of the genus are of veterinary importance, and there have been scattered reports of febrile illnesses in humans associated with several other viruses in the genus (Parsonson and McPhee, 1985; Shope, 1985). Table I lists the members of the genus that are known to cause disease in either humans or animals.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 219.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Similar content being viewed by others

References

  • Aguirre, A. A., McLean, R. G., Cook, R. S., and Quan, T. J., 1992, Serologic survey for selected arboviruses and other potential pathogens in wildlife from Mexico, J. Wildl. Dis. 28:435.

    PubMed  CAS  Google Scholar 

  • Al-Busaidy, S. M., and Mellor, P. S., 1991, Isolation and identification of arboviruses from the Sultanate of Oman, Epidemiol. Infect. 106:403.

    Article  PubMed  CAS  Google Scholar 

  • Al-Busaidy, S., Hamblin, C., and Taylor, W. P., 1987, Neutralising antibodies to Akabane virus in free-living wild animals in Africa, Trop. Anim. Health Prod. 19:197.

    Article  PubMed  CAS  Google Scholar 

  • Al-Busaidy, S. M., Mellor, P. S., and Taylor, W. P., 1988, Prevalence of neutralising antibodies to Akabane virus in the Arabian peninsula, Vet. Microbiol. 17:141.

    Article  PubMed  CAS  Google Scholar 

  • Anderson, C. R., Spence, L., Downs, W. G., and Aitken, T. H. G., 1961, Oropouche virus: A new human disease agent from Trinidad, West Indies, Am. J. Trop. Med. Hyg. 10:574.

    PubMed  CAS  Google Scholar 

  • Artsob, H., 1983, Distribution of California serogroup viruses and virus infection in Canada, in: California Serogroup Viruses (C. H. Calisher and W. H. Thompson, eds.), pp. 277-292, Liss, New York.

    Google Scholar 

  • Balfour, H. H., Edelman, C. K., Cook, F. E., Barton, W. I., Buzicky, A. W., Siem, R. A., and Bauer, H., 1975, Isolates of California encephalitis (La Crosse) virus from field-collected eggs and larvae of Aedes triseriatus: Identification of the overwintering site of California encephalitis, J. Infect. Dis. 131:712.

    Article  PubMed  Google Scholar 

  • Bardos, V., 1965, Tahyna virus in experimentally infected white mice, Acta Virol. 9:358.

    PubMed  CAS  Google Scholar 

  • Bardos, V., 1969, On the pathogenesis of California complex virus infectons, in: Arboviruses of the California Complex and the Bunyamwera Group (V. Bardos, ed.), pp. 229-236, Slovak Academy of Sciences, Bratislava.

    Google Scholar 

  • Beaty, B. J., and Thompson, W. H., 1975, Emergence of La Crosse virus from endemic foci, Am. J. Trop. Med. Hyg. 24:685.

    PubMed  CAS  Google Scholar 

  • Beaty, B. J., Miller, B. R., Shope, R. E., Rozhon, E. J., and Bishop, D. H., 1982, Molecular basis of bunyavirus per os infection of mosquitoes: Role of the middle-sized RNA segment, Proc. Natl. Acad. Sci. USA 79:1295.

    Article  PubMed  CAS  Google Scholar 

  • Berry, R. L., Parsons, M. A., Restifo, R. A., Peterson, E. O., Gordon, S. W., Reed, M. R., Calisher, C. H., Bear, G. T., and Halpin, T. J., 1983, California serogroup virus infections in Ohio: An 18-year retrospective summary, in: California Serogroup Viruses (C. H. Calisher and W. H. Thompson, eds.), pp. 215-223, Liss, New York.

    Google Scholar 

  • Bishop, D. H. L., and Shope, R. E., 1979, Bunyaviridae, Comp. Virol. 14:1.

    Article  CAS  Google Scholar 

  • Bishop, D. H. L., Calisher, C. H., Casals, J., Chumakov, M. P., Gaidamovich, S. Y., Hannoun, C., Lvov, D. K., Marshall, I. D., Oker-Blom, N., Pettersson, R. F., Porterfield, J. S., Russell, P. K., and Shope, R. E., 1980, Bunyaviridae, Intervirology 14:125.

    Article  PubMed  CAS  Google Scholar 

  • Burton, A. N., McLintock, J., and Francy, D. B., 1973, Isolation of St. Louis encephalitis and Cache Valley viruses from Saskatchewan mosquitoes, Can. J. Public Health 64:368.

    PubMed  CAS  Google Scholar 

  • Calisher, C. H., 1983, Taxonomy, classification, and geographic distribution of California serogroup bunyaviruses, in: California Serogroup Viruses (C. H. Calisher and W. H. Thompson, eds.), pp. 1-18, Liss, New York.

    Google Scholar 

  • Calisher, C. H., Francy, D. B., Smith, G. C., Muth, D. J., Lazuick, J. S., Karabatsos, N., Jakob, W. L., and McLean, R. G., 1986, Distribution of Bunyamwera serogroup viruses in North America, Am. J. Trop. Med. Hyg. 35:429.

    PubMed  CAS  Google Scholar 

  • Calisher, C. H., Monath, T. P., Sabattini, M. S., Mitchell, C. J., Lazuick, J. S., Tesh, R. B., and Cropp, C. B., 1987, A newly recognized vesiculovirus, Calchaqui virus, and subtypes of Melao and Maguari viruses from Argentina, with serologic evidence for infections of humans and horses, Am. J. Trop. Med. Hyg. 36:114.

    PubMed  CAS  Google Scholar 

  • Calisher, C. H., Lazuick, J. S., Lieb, S., Monath, T. P., and Castro, K. G., 1988a, Human infections with Tensaw virus in South Florida: Evidence that Tensaw virus subtypes stimulate the production of antibodies reactive with closely related Bunyamwera serogroup viruses, Am. J. Trop. Med. Hyg. 39:117.

    PubMed  CAS  Google Scholar 

  • Calisher, C. H., Oro, J. G. B., Lord, R. D., Sabattini, M. S., and Karabatsos, N., 1988b, Kairi virus identified from a febrile horse in Argentina, Am. J. Trop. Med. Hyg. 39:519.

    PubMed  CAS  Google Scholar 

  • Campbell, G. L., Reeves, W. C., Hardy, J. L., and Eldridge, B. F., 1992, Seroepidemiology of California and Bunyamwera serogroup Bunyavirus infections in humans in California, Am. J. Epidemiol. 136:308.

    PubMed  CAS  Google Scholar 

  • Chandler, J. F., Hogge, G., Endres, M., Jacoby, D. R., Nathanson, N., and Beatty, B., 1991, Reassortment of La Crosse and Tahyna bunyaviruses in Aedes triseriatus mosquitoes, Virus Res. 20:181.

    Article  PubMed  CAS  Google Scholar 

  • Chun, R. W. M., 1983, Clinical aspects of La Crosse encephalitis: Neurological and psychological sequelae, in: California Serogroup Viruses (C. H. Calisher and W. H. Thompson, eds.), pp. 193-201, Liss, New York.

    Google Scholar 

  • Chun, R. W. M., Thompson, W. H., Grabow, J. D., and Matthews, C. G., 1968, California arbovirus encephalitis in children, Neurology 18:369.

    Article  PubMed  CAS  Google Scholar 

  • Chung, S. I., Livingston, C. W., Jr., Edwards, J. F., Gauer, B. B., and Collisson, E. W., 1990, Congenital malformations in sheep resulting from in utero innoculation of Cache Valley virus, Am. J. Vet. Res. 51:1645.

    PubMed  CAS  Google Scholar 

  • Clark, G. G., Crabbs, C. L., Bailey, C. L., Calisher, C. H., and Craig, G. B., Jr., 1986, Identification of Aedes campestris from New Mexico: With notes on the isolation of Western equine encephalitis and other arboviruses, J. Am. Mosq. Control Assoc. 2:529.

    PubMed  CAS  Google Scholar 

  • Crandell, R. A., Livingston, C. W., Jr., and Shelton, M. J., 1989, Laboratory investigation of a naturally occurring outbreak of arthrogryposis-hydranencephaly in Texas sheep, J. Vet. Diagn. Invest. 1:62.

    Article  PubMed  CAS  Google Scholar 

  • Danielova, V., 1974, The property changes of two Tahyna virus strains by influence of serial passages in various environments, Z., Bakteriol. Hyg. 229:323.

    CAS  Google Scholar 

  • Dargan, D. J., Galt, C. B., and Subak-Sharpe, J. H., 1992, The effect of cicloxolone sodium on the replication in cultured cells of adenovirus type 5, reovirus type 3, poliovirus type 1, two bunyaviruses and Semliki Forest virus, J. Gen. Virol. 73:407.

    Article  PubMed  CAS  Google Scholar 

  • Davies, F. G., and Jessett, D. M., 1985, A study of the host range and distribution of antibody to Akabane virus (genus Bunyavirus, family Bunyaviridae) in Kenya, J. Hyg. Cambridge 95:191.

    Article  CAS  Google Scholar 

  • DeFoliart, G. R., 1983, Aedes triseriatus: Vector biology in relationship to the persistence of La Crosse virus in endemic foci, in: California Serogroup Viruses (C. H. Calisher and W. H. Thompson, eds.), pp. 89-105, Liss, New York.

    Google Scholar 

  • Deibel, R., Srihongse, S., Grayson, M. A., Grimstad, P. R., Mahdy, M. S., Artsob, H., and Calisher, C. H., 1983, Jamestown Canyon virus: The etiologic agent of an emerging human disease? in: California Serogroup Viruses (C. H. Calisher and W. H. Thompson, eds.), pp. 313-328, Liss, New York.

    Google Scholar 

  • Dixon, K. E., Travassos da Rosa, A. P. A., Travassos da Rosa, J. F., and Llewellyn, C. H., 1981, Oropouche virus. II. Epidemiological observations during an epidemic in Santarem, Para, Brazil in 1975, Am. J. Trop. Med. Hyg. 30:161.

    PubMed  CAS  Google Scholar 

  • Edwards, J. F., Livingston, C. W., Chung, S.I., and Collisson, E. C., 1989, Ovine arthrogryposis and central nervous system malformations associated with in utero Cache Valley virus infection: Spontaneous disease, Vet. Pathol. 26:33.

    Article  PubMed  CAS  Google Scholar 

  • Eldridge, B. F., Calisher, C. H., Fryer, J. L., Bright, L., and Hobbs, D. J., 1987, Serological evidence of California serogroup virus activity in Oregon, J. Wildl. Dis. 23:199.

    PubMed  CAS  Google Scholar 

  • Elliott, R. M., and Wilkie, M. L., 1986, Persistent infection of Aedes albopictus C6/36 cells by Bunyamwera virus, Virology 150:21.

    Article  PubMed  CAS  Google Scholar 

  • Endres, M. J., Valsamakis, A., Gonzalez-Scarano, F., and Nathanson, N. A., 1990, Neuroattenuated bunyavirus variant: Derivation, Characterization and revertant clones, J. Virol. 64:1927.

    PubMed  CAS  Google Scholar 

  • Francy, D. B., Karabatsos, N., Wesson, D. M., Moore, C. G., Jr., Lazuick, J. S., Niebylski, M. L., Tsai, T. F., and Craig, G. B., Jr., 1990, A new arbovirus from Aedes albopictus, an Asian mosquito established in the United States, Science 250:1738.

    Article  PubMed  CAS  Google Scholar 

  • Gauld, L. W., Hanson, R. P., Thompson, W. H., and Sinha, S. K., 1974, Observations on a natural cycle of La Crosse virus (California group) in southwestern Wisconsin, Am. J. Trop. Med. Hyg. 23:983.

    PubMed  CAS  Google Scholar 

  • Gonzalez-Scarano, F., Shope, R. E., Calisher, C. H., and Nathanson, N., 1982, Characterization of monoclonal antibodies against the G1 and N proteins of La Crosse and Tahyna, two California serogroup bunyaviruses, Virology 120:42.

    Article  PubMed  CAS  Google Scholar 

  • Gonzalez-Scarano, F., Janssen, R., Najjar, J. A., Pobjecky, N., and Nathanson, N., 1985, An avirulent G1 glycoprotein variant of La Crosse bunyavirus with a defective fusion function, J. Virol. 54:757.

    PubMed  CAS  Google Scholar 

  • Grady, L. J., Srihongse, S., Grayson, M. A., and Deibel, R., 1983, Monoclonal antibodies against La Crosse virus, J. Gen. Virol. 64:1699.

    Article  PubMed  Google Scholar 

  • Grimstad, P. R., Calisher, C. H., Haroff, R. N., Wentworth, B. B., 1984a, Jamestown Canyon virus (California serogroup) is the etiologic agent of widespread infection in Michigan humans, Am. J. Trop. Med. Hyg. 35:376.

    Google Scholar 

  • Grimstad, P. R., Barrett, R. L., Humphrey, R. L., Sinsko, M. V., 1984b, Serologic evidence for widespread infection with La Crosse and St. Louis encephalitis viruses in the Indiana human population, Am. J. Epidemiol. 119:913.

    PubMed  CAS  Google Scholar 

  • Griot, C., Gonzalez-Scarano, F., and Nathanson, N., 1993a, Molecular determinants of the virulence and infectivity of California serogroup bunyaviruses, Annu. Rev. Microbiol. 47:117.

    Article  PubMed  CAS  Google Scholar 

  • Griot, C., Pekosz, A., Lukac, D., Scherer, S. S., Stillmock, K., Schmeidler, D., Endres, M. J., Gonzalez-Scarano, F., and Nathanson, N., 1993b, Polygenic control of neuroinvasiveness in California serogroup bunyaviruses, J. Virol. 67:3861.

    PubMed  CAS  Google Scholar 

  • Griot, C., Pekosz, A., Davidson, R., Stillmock, K., Hoek, M., Lukac, D., Schmeidler, D., Cobbinah, I., Gonzalez-Scarano, F., and Nathanson, N., 1994, Replication in cultured C2C12 muscle cells correlates with the neuroinvasiveness of California serogroup bunyaviruses, Virology 201:399.

    Article  PubMed  CAS  Google Scholar 

  • Gundersen, C. B., and Brown, K. L., 1983, Clinical aspects of La Crosse encephalitis: Preliminary report, in: California Serogroup Viruses (C. H. Calisher and W. H. Thompson, eds.), pp. 169-177, Liss, New York.

    Google Scholar 

  • Gundlach, A. L., Grabara, C. S. G., Johnston, G. A. R., and Harper, P. A. W., 1990, Receptor alterations associated with spinal motoneuron degeneration in bovine Akabane disease, Ann. Neurol. 27:513.

    Article  PubMed  CAS  Google Scholar 

  • Hamblin, C., Anderson, E. C., Jago, M., Mlengeya, T., and Hirji, K., 1990, Antibodies to some pathogenic agents in free-living wild species in Tanzania, Epidemiol. Infect. 105:585.

    Article  PubMed  CAS  Google Scholar 

  • Hammon, W. McD., and Reeves, W. C., 1952, California encephalitis virus—a newly described agent. I. Evidence of natural infection in man and other animals, Calif. Med. 77:303.

    PubMed  CAS  Google Scholar 

  • Haziroglu, R., Haritani, M., and Narita, M., 1987, Demonstration of Akabane virus antigen in experimentally infected mice using immunoperoxidase method, Jpn. J. Vet. Sci. 49:133.

    Article  CAS  Google Scholar 

  • Henderson, B. E., and Coleman, P. H., 1971, The growing importance of California arboviruses in the etiology of human disease, Prog. Med. Virol. 13:404.

    PubMed  CAS  Google Scholar 

  • Hoch, A. L., Pinheiro, F. P., Roberts, D. R., and Gomes, M. D. C., 1987, Laboratory transmission of Oropouche virus by Culex quinquefasciatus Say, PAHO Bull. 21:55.

    CAS  Google Scholar 

  • Hoffmann, D., and St. George, T. D., 1985, Growth of epizootic hemorrhagic disease, Akabane, and ephemeral fever viruses in Aedes albopictus cells maintained at various temperatures, Aust. J. Biol. Sci. 38:183.

    PubMed  CAS  Google Scholar 

  • Iversen, J. O., Wagner, R. J., and Leung, M. K., 1979, Cache Valley virus: Isolations from mosquitoes in Saskatchewan, 1972–1974, Can. J. Microbiol. 25:760.

    Article  PubMed  CAS  Google Scholar 

  • Iversson, L. B., Travassos da Rosa, A. P. A., Coimbra, T. L. M., Ferreira, I. B., and Nassar, E. D., 1987, Human disease in Ribeira Valley, Brazil caused by Caraparu, a Group C arbovirus— Report of a case, Rev. Inst. Med. Trop. Sao Paulo 29:112.

    Article  PubMed  CAS  Google Scholar 

  • Jakob, W. L., Davis, T., and Francy, D. B., 1989, Occurrence of Culex erythrothorax in southeastern Colorado and report of virus isolations from this and other mosquito species, J. Am. Mosq. Control Assoc. 5:534.

    PubMed  CAS  Google Scholar 

  • James, W. S., and Millican, D., 1986, Host-adaptive antigenic variation in Bunyaviruses, J. Gen. Virol. 67:2803.

    Article  PubMed  Google Scholar 

  • Janssen, R., Gonzalez-Scarano, F., and Nathanson, N., 1984, Mechanisms of bunyavirus virulence. Comparative pathogenesis of a virulent strain of La Crosse and an avirulent strain of Tahyna virus, Lab. Invest. 50:447.

    PubMed  CAS  Google Scholar 

  • Janssen, R. S., Nathanson, N., Endres, M. J., and Gonzalez-Scarano, F., 1986, Virulence of La Crosse virus is under polygenic control, J. Virol. 59:1.

    PubMed  CAS  Google Scholar 

  • Johnson, K. P., and Johnson, R. T., 1968, California encephalitis. II. Studies of experimental infection in the mouse, J. Neuropathol. Exp. Neurol 27:390.

    Article  Google Scholar 

  • Jonkers, A. H., Spence, L., Downs, W. G., Aitken, T. H. G., and Tikasingh, E. S., 1968, Arbovirus studies in Bush forest, Trinidad, W. I., September 1959–December 1964, Am. J. Trop. Med. Hyg. 17:276.

    PubMed  CAS  Google Scholar 

  • Kalfayan, B., 1983, Pathology of La Crosse virus infection in humans, in: California Serogroup Viruses (C. H. Calisher and W. H. Thompson, eds.), pp. 179-186, Liss, New York.

    Google Scholar 

  • Kappus, K. D., Monath, T. P., Kaminski, R. M., and Calisher, C. H., 1983, Reported encephalitis associated with California serogroup virus infections in the United States, 1963-1981, in: California Serogroup Viruses (C. H. Calisher and W. H. Thompson, eds.), pp. 31-41, Liss, New York.

    Google Scholar 

  • Kingsford, L., 1991, Antigenic variance, Curr. Top. Microbiol. Immunol. 169:181.

    Article  PubMed  CAS  Google Scholar 

  • Kingsford, L., Ishizawa, L. D., and Hill, D. W., 1983, Biological activities of monoclonal antibodies reactive with antigenic sites mapped on the G1 glycoprotein of La Crosse virus, Virology 129:443.

    Article  PubMed  CAS  Google Scholar 

  • Kingsford, L., Boucquey, K. H., and Cardoso, T. P., 1991, Effects of specific monoclonal antibodies on La Crosse virus neutralization: Aggregation, inactivation by Fab fragments, and inhibition of attachment to baby hamster kidney cells, Virology 180:591.

    Article  PubMed  CAS  Google Scholar 

  • Kirkland, P. D., Barry, R. D., Harper, P. A. W., and Zelski, R. Z., 1988, The development of Akabane virus-induced congenital abnormalities in cattle, Vet. Rec. 122:582.

    Article  PubMed  CAS  Google Scholar 

  • Kokernot, R. H., Smithburn, K. C., de Meillon, B., and Paterson, H. E., 1958, Isolation of Bunyamwera virus from a naturally infected human being and further isolations from Aedes (Banksinella) Circumluteolus theo, Am. J. Trop. Med. Hyg. 7:579.

    PubMed  CAS  Google Scholar 

  • Konno, S., Koeda, T., Madarame, H., Ikeda, S., Sasaki, T., Satoh, H., and Nakano, K., 1988, Myopathy and encephalopathy in chick embryos experimentally infected with Akabane virus, Vet. Pathol. 25:1.

    Article  PubMed  CAS  Google Scholar 

  • Kramer, W. L., Jones, R. H., Holbrook, F. R., Walton, T. E., and Calisher, C. H., 1990, Isolation of arboviruses from Culicoides Midges (Diptera: Ceratopogonidae) in Colorado during an epizootic of vesicular stomatitis New Jersey, J. Med. Entomol. 27:487.

    PubMed  CAS  Google Scholar 

  • Ksiazek, T. G., and Yuill, T. M., 1977, Viremia and antibody response to La Crosse virus in sentinel gray squirrels (Sciuris carolinensis) and chipmunks (Tamias striatus), Am. J. Trop. Med. Hyg. 26:815.

    PubMed  CAS  Google Scholar 

  • Kurogi, H., Inaba, Y., Takahashi, E., Sato, K., Omori, T., Miura, Y., Goto, Y., Fujiwara, Y., Hatano, Y., Kodama, K., Fukuyama, S., Sasaki, N., and Matumoto, M., 1976, Epozootic congenital arthrogryposis-hydranencephaly syndrome in cattle: Isolation of Akabane virus from affected fetuses, Arch. Virol. 51:67.

    Article  PubMed  CAS  Google Scholar 

  • Kurogi, H., Inaba, Y., Takahashi, E., Sato, K., Satoda, K., Goto, Y., Omori, T., and Matumoto, M., 1977, Congenital abnormalities in newborn calves after inoculation of pregnant cows with Akabane virus, Infect. Immun. 17:338.

    PubMed  CAS  Google Scholar 

  • Kurogi, H., Inaba, Y., Takahashi, E., Sato, K., Goto, Y., Satoda, K., Omori, T., and Hatakeyama, H., 1978, Development of inactivated vaccine for Akabane disease, Natl. Inst. Anim. Health Q. 18:97.

    CAS  Google Scholar 

  • Kurogi, H., Inaba, Y., Takahashi, E., Sato, K., Akashi, H., Satoda, K., and Omori, T, 1979, An attenuated strain of Akabane virus: A candidate for live virus vaccine, Natl. Inst. Anim. Health Q. 19:12.

    CAS  Google Scholar 

  • LeDuc, J. W., 1987, Epidemiology of Hantaan and related viruses, Lab. Anim. Sci. 37:413.

    PubMed  CAS  Google Scholar 

  • LeDuc, J. W., Suyemoto, W., Keefe, T. J., Burger, J. F., Eldridge, B. F., and Russell, P. K., 1975a, Ecology of California encephalitis viruses on the Del Mar Va peninsula. I. Virus isolations from mosquitoes, Am. J. Trop. Med. Hyg. 24:118.

    CAS  Google Scholar 

  • LeDuc, J. W., Suyemoto, W., Eldridge, B. F., Russell, P. K., and Barr, A. R., 1975b, Ecology of California encephalitis viruses on the Del Mar Va peninsula. II. Demonstration of transovarial transmission, Am. J. Trop. Med. Hyg. 24:124.

    CAS  Google Scholar 

  • Ludwig, G. V., Israel, B. A., Christensen, B. M., Yuill, T. M., and Schultz, K. T., 1991, Monoclonal antibodies directed against the envelope glycoproteins of La Crosse virus, Microb. Pathogen. 11:411.

    Article  CAS  Google Scholar 

  • Lyons, M. J., and Heyduk, J., 1973, Aspects of the developmental morphology of California encephalitis virus in cultured vertebrate and arthropod cells and in mouse brain, Virology 54:37.

    Article  PubMed  CAS  Google Scholar 

  • McClure, S., McCullagh, P., Parsonson, I. M., McPhee, D. A., Della-Porta, A. J., and Orsini, A., 1988, Maturation of immunological reactivity in the fetal lamb infected with Akabane virus, J. Comp. Pathol. 99:133.

    Article  PubMed  CAS  Google Scholar 

  • McLean, D. M., Gubash, S. M., Grass, P. N., Miller, M. A., Petric, M., and Walters, T. E., 1975, California encephalitis virus development in mosquitoes as revealed by transmission studies, immunoperoxidase staining, and electron microscopy, Can. J. Microbiol. 21:453.

    Article  PubMed  CAS  Google Scholar 

  • McLean, D. M., Grass, P. N., Judd, B. D., and Stolz, K. J., 1979, Bunyavirus development in arctic and Aedes aegypti mosquitoes as revealed by glucose oxidase staining and immunofluorescence, Arch. Virol. 62:313.

    Article  PubMed  CAS  Google Scholar 

  • McLean, R. G., Calisher, C. H., and Parham, G. L., 1987, Isolation of Cache Valley virus and detection of antibody for selected arboviruses in Michigan horses in 1980, Am. J. Vet. Res. 48:1039.

    PubMed  CAS  Google Scholar 

  • Main, A. J., and Crans, W. J., 1986, Cache Valley virus from Aedes sollicitans in New Jersey, J. Am. Mosq. Control Assoc. 2:95.

    PubMed  CAS  Google Scholar 

  • Malkova, D., 1971, Virulence of Tahyna virus in mice and its relation to thermosensitivity and character of plaque population markers, Acta Virol. 15:473.

    PubMed  CAS  Google Scholar 

  • Malkova, D., and Marhoul, Z., 1971, Plaquing of different strains of Tahyna virus in GMK cells, Acta Virol. 15:227.

    PubMed  CAS  Google Scholar 

  • Mangiafico, J. A., Sanchez, J. L., Figueiredo, L. T., LeDuc, W., and Peters, C. J., 1988, Isolation of a newly recognized Bunyamwera serogroup virus from a febrile human in Panama, Am. J. Trop. Med. Hyg. 39:593.

    PubMed  CAS  Google Scholar 

  • Miller, B. R., 1983, A variant of La Crosse virus attenuated for Aedes triseriatus mosquitoes, Am. J. Trop. Med. Hyg. 32:1422.

    PubMed  CAS  Google Scholar 

  • Mitchell, C. J., Lvov, S. D., Savage, H. M., Calisher, C. H., Smith, G. C., Lvov, D. K., and Gubler, D. J.;, 1993, Vector and host relationships of California serogroup viruses in western Siberia, Am. J. Trop. Med. Hyg. 49:53.

    PubMed  CAS  Google Scholar 

  • Monath, T. P. C., Nuckolls, J. G., Berall, J., Bauer, H., Chappell, W. A., and Coleman, P. H., 1970, Studies of California encephalitis in Minnesota, Am. J. Epidemiol. 92:40.

    PubMed  CAS  Google Scholar 

  • Murphy, F. A., Whitfield, S. G., Coleman, P. H., and Calisher, C. H., 1968, California group arboviruses: Electron microscopic studies, Exp. Mol. Pathol. 9:44.

    Article  PubMed  CAS  Google Scholar 

  • Narita, M., and Kawashima, K., 1993, Detection of Akabane viral antigen and immunoglobulincontaining cells in ovine fetuses by use of immunoperoxidase staining, Am. J. Vet. Res. 54:420.

    PubMed  CAS  Google Scholar 

  • Neitzel, D. F., and Grimstad, P. R., 1991, Serological evidence of California group and Cache Valley virus infection in Minnesota white-tailed deer, J. Wildl. Dis. 27:230.

    PubMed  CAS  Google Scholar 

  • Newton, S. E., Short, N. J., and Dalgarno, L., 1981, Bunyamwera virus replication in cultured Aedes albopictus (mosquito) cells: Establishment of a persistent viral infection, J. Virol. 38:1015.

    PubMed  CAS  Google Scholar 

  • Oya, A., Okuno, T., Ogata, T., Kobayashi, I., and Matsuyama, T., 1961, Akabane, a new arbovirus isolated in Japan, Jpn. J. Med. Sci. Biol. 14:101.

    PubMed  CAS  Google Scholar 

  • Pantuwatana, S., Thompson, W. H., Watts, D. M., and Hanson, R. F., 1972, Experimental infection of chipmunks and squirrels with La Crosse and Trivittatus viruses and biological transmission of La Crosse viruse by Aedes triseriatus, Am. J. Trop. Med. Hyg., 21:476.

    PubMed  CAS  Google Scholar 

  • Parsonson, I. M., and McPhee, D. A., 1985, Bunyavirus pathogenesis, Adv. Virus Res. 30:279.

    Article  PubMed  CAS  Google Scholar 

  • Parsonson, I. M., Della-Porta, A. J., and Snowdon, W. A., 1977, Congenital abnormalities in newborn lambs after infection of pregnant sheep with Akabane virus, Infect. Immun. 15:254.

    PubMed  CAS  Google Scholar 

  • Parsonson, I. M., McPhee, D. A., Della-Porta, A. J., McClure, S., and McCullagh, P., 1988, Transmission of Akabane virus from the ewe to the early fetus (32 to 53 days), J. Comp. Pathol. 98:215.

    Article  Google Scholar 

  • Patrican, L. A., DeFoliart, G. R., and Yuill, T. M., 1985, La Crosse viremias in juvenile, subadult and adult chipmunks (Tamias striatus) following feeding by transovarially-infected Aedes triseriatus, Am. J. Trop. Med. Hyg. 34:596.

    PubMed  CAS  Google Scholar 

  • Pekosz, A., Griot, C., Nathanson, N., and González-Scarano, F., 1996, Tropism of Bunyaviruses: Evidence for a G1 glycoprotein mediated entry pathway common to the California serogroup, Virology, in press.

    Google Scholar 

  • Pekosz, A., Griot, C., Stillmock, K., Nathanson, N., and González-Scarano, F., 1995, Protection from La Crosse virus encephalitis with recombinant glycoproteins: Role of neutralizing anti-G1 antibodies, J. Virol. 69:3475–3481.

    PubMed  CAS  Google Scholar 

  • Pinheiro, F. P., Hoch, A. L., Gomes, M. D. C., and Roberts, D. R., 1981a, Oropouche virus. IV. Laboratory transmission by Culicoides paraensis, Am. J. Trop. Med. Hyg. 30:172.

    PubMed  CAS  Google Scholar 

  • Pinheiro, F. P., Travassos da Rosa, A. P. A., Travassos da Rosa, J. F. S., Ishak, R., Freitas, R. B., Gomes, M. L. C., LeDuc, J. W., and Oliva, O. F. P., 1981b, Oropouche virus: A review of clinical, epidemiological, and ecological findings, Am. J. Trop. Med. Hyg. 30:149.

    PubMed  CAS  Google Scholar 

  • Pinheiro, F. P., Travassos da Rosa, A. P. A., Gomes, M. L. C., LeDuc, J. W., and Hoch, A. L., 1982, Transmission of Oropouche virus from man to hamster by the midge, Culicoides paraensis, Science 215:1251.

    CAS  Google Scholar 

  • Reeves, W. C., and Hammon, W. McD., 1962, Epidemiology of the arthropod-borne viral encephalitides in Kern County, California, 1943–1952, Univ. Calif. Publ. Public Health 4:1.

    CAS  Google Scholar 

  • Reeves, W. C., Emmons, R. W., and Hardy, J. L., 1983, Historical perspective on California encephalitis virus in California, in: California Serogroup Viruses (C. H. Calisher and W. H. Thompson, eds.), pp. 19-30, Liss, New York.

    Google Scholar 

  • Roberts, A., Rossier, Kolakofsky, D., Nathanson, N., and Gonzáles-Scarano, F., 1995, Completion of the La Crosse virus genome sequence and genetic comparisons of the L proteins of the Bunyaviridae, Virology 206:742–745.

    Article  PubMed  CAS  Google Scholar 

  • Roberts, D. R., Hoch, A. L., Dixon, K. E., and Llewellyn, C. H., 1981, Oropouche virus. III. Entomological observations from three epidemics in Para, Brazil, 1975, Am. J. Trop. Med. Hyg. 30:165.

    PubMed  CAS  Google Scholar 

  • Rodhain, F., Gonzalez, J. P., Mercier, E., Helynck, B., Larouze, B., and Hannoun, C., 1989, Arbovirus infections and viral haemorrhagic fevers in Uganda: A serological survey in Karamoja district, 1984, Trans. R. Soc. Trop. Med. Hyg. 83:851.

    Article  PubMed  CAS  Google Scholar 

  • Rowley, W. A., Wong, Y. W., Dorsey, D. C., Hausier, R. V., and Currier, R. W., 1983, California serogroup viruses in Iowa, in: California Serogroup Viruses (C. H. Calisher and W. H. Thompson, eds.), pp. 237-246, Liss, New York.

    Google Scholar 

  • Schopen, S., Labuda, M., and Beaty, B., 1991, Vertical and veneral transmission of California group viruses by Aedes triseriatus and Culiseta inornata mosquitoes, Acta Virol., 35:373.

    PubMed  CAS  Google Scholar 

  • Sellers, R. F., and Pedgley, D. E., 1985, Possible windborne spread to western Turkey of bluetongue virus in 1977 and of Akabane virus in 1979, J. Hyg. Cambridge 95:149.

    Article  CAS  Google Scholar 

  • Seymour, C., Amundson, T. E., Yuill, T. M., and Bishop, D. H. L., 1983, Experimental infection of chipmunks and snowshoe hares with La Crosse and snowshoe hare viruses and four of their reassortants, Am. J. Trop. Med. Hyg. 32:1147.

    PubMed  CAS  Google Scholar 

  • Shope, R. E., 1985, Bunyaviruses, in: Virology (B. N. Fields, ed.), pp. 1055–1082, Raven Press, New York.

    Google Scholar 

  • Smith, G. C., and Francy, D. B., 1991, Laboratory studies of a Brazilian strain of Aedes albopictus as a potential vector of Mayaro and Oropouche viruses, J. Am. Mosq. Control Assoc. 7:89.

    PubMed  CAS  Google Scholar 

  • Smithburn, K. C., Haddow, A. J., and Mahaffy, A. F., 1946, A neurotropic virus isolated from Aedes mosquitos caught in the Semliki Forest, Am. J. Trop. Med. 26:189.

    CAS  Google Scholar 

  • Srihongse, S., Grayson, M. A., and Diebel, R., 1984, California serogroup viruses in New York State: The role of subtypes in human infections, Am. J. Trop. Med. Hyg. 33:1218.

    PubMed  CAS  Google Scholar 

  • Sundin, D. R., Beaty, B. J., Nathanson, N., and Gonzalez-Scarano, F., 1987, A G1 glycoprotein epitope of La Crosse virus: A determinant of infection of Aedes triseriatus, Science 235:591.

    Article  PubMed  CAS  Google Scholar 

  • Tesh, R. B., and Beaty, B. J., 1983, Localization of California serogroup viruses in mosquitoes, in: California Serogroup Viruses (C. H. Calisher and W. H. Thompson, eds.), pp. 67-75, Liss, New York.

    Google Scholar 

  • Theiler, M., and Downs, W. G., 1973, Bunyamwera supergroup, in: The Arthropod-borne Viruses of Vertebrates, pp. 209–262, Yale University Press, New Haven, CT.

    Google Scholar 

  • Thompson, W. H., 1983, Vector-virus relationships, in: California Serogroup Viruses (C. H. Calisher and W. H. Thompson, eds.), pp. 57-66, Liss, New York.

    Google Scholar 

  • Thompson, W. H., and Beaty, B. J., 1978, Venereal transmission of La Crosse virus from male to female Aedes triseriatus, Am. J. Trop. Med. Hyg. 27:187.

    PubMed  CAS  Google Scholar 

  • Thompson, W. H., Kalfayan, B., and Anslow, R. O., 1965, Isolation of California encephalitis group virus from a fatal human illness, Am. J. Epidemiol. 81:245.

    PubMed  CAS  Google Scholar 

  • Tignor, G. H., Burrage, T. G., Smith, A. L., and Shope, R. E., 1983, California serogroup gene structure-function relationships; virulence and tissue tropisms, in: California Serogroup Viruses (C. H. Calisher and W. H. Thompson, eds.), pp. 129-138, Liss, New York.

    Google Scholar 

  • Traavik, T., Mehl, R., and Wiger, R., 1978, California encephalitis group viruses isolated from mosquitoes collected in southern and arctic Norway, Acta Pathol. Microbiol. Scand. 86:335.

    Google Scholar 

  • Traavik, T., Mehl, R., and Wiger, R., 1985, Mosquito-borne arboviruses in Norway: Further isolations and detection of antibodies to California encephalitis viruses in human, sheep and wildlife sera, J. Hyg. Cambridge 94:111.

    Article  CAS  Google Scholar 

  • Turell, M. J., and Hardy, J. L., 1980, Carbon dioxide sensitivity of mosquitoes infected with California encephalitis virus, Science 209:1029.

    Article  PubMed  CAS  Google Scholar 

  • Turell, M. J., and LeDuc, J. W., 1983, The role of mosquitoes in the natural history of California serogroup viruses, in: California Serogroup Viruses (C. H. Calisher and W. H. Thompson, eds.), pp. 43-56, Liss, New York.

    Google Scholar 

  • Turell, M. J., Gargan, T. P., and Bailey, C. L., 1984, Replication and dissemination of Rift Valley fever virus in Culex pipiens, Am. J. Trop. Med. Hyg. 33:176.

    PubMed  CAS  Google Scholar 

  • Tyler, K. L., McPhee, D. A., and Fields, B. N., 1986, Distinct pathways of viral spread in the host determined by reovirus S1 gene segment, Science 233:770.

    Article  PubMed  CAS  Google Scholar 

  • Wallnerova, A., 1969, Fluorescent antibody technique in study of experimental Tahyna and La Crosse virus infections in suckling mice, in: Arboviruses of the California Complex and the Bunyamwera Group (V. Bardos, ed.), pp. 237-246, Slovak Academy of Sciences, Bratislava.

    Google Scholar 

  • Watts, D. M., Pantuwatana, S., DeFoliart, G. R., Yuill, T. M., and Thompson, W. H., 1973, Transovarial transmission of La Crosse virus (California encephalitis group) in the mosquito, Aedes triseriatus, Science 182:1140.

    Article  PubMed  CAS  Google Scholar 

  • Way, H. J., Bowen, E. T. W., and Platt, G. S., 1976, Comparative studies of some African arboviruses in cell culture in mice, J. Gen. Virol. 30:123.

    Article  PubMed  CAS  Google Scholar 

  • Whitman, L., and Shope, R. E., 1962, The California complex of arthropod-borne viruses and its relationship to the Bunyamwera group through Guaroa virus, Am. J. Trop. Med. Hyg. 11:691.

    PubMed  CAS  Google Scholar 

  • Woodruff, B. A., Baron, R. C., and Tsai, T. F., 1992, Symptomatic La Crosse virus infections of the central nervous system: A study of risk factors in an endemic area, Am. J. Epidemiol. 136:320.

    PubMed  CAS  Google Scholar 

  • Woodruff, P. W. R., Morrill, J. C., Burans, J. P., Hyams, K. C., and Woody, J. N., 1988, A study of viral and rickettsial exposure and causes of fever in Juba, southern Sudan, Trans. R. Soc. Trop. Med. Hyg. 82:761.

    Article  PubMed  CAS  Google Scholar 

  • Worth, C. B., Paterson, H. E., and de Meillon, B., 1961, The incidence of arthropod-borne viruses in a population of culicine mosquitoes in Tongaland, Union of South Africa (January, 1956, through April, 1960), Am. J. Trop. Med. Hyg. 10:583.

    PubMed  CAS  Google Scholar 

  • Yuill, T. M., 1983, The role of mammals in the maintenance and dissemination of La Crosse virus, in: California Serogroup Viruses (C. H. Calisher and W. H. Thompson, eds.), pp. 77-88, Liss, New York.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1996 Springer Science+Business Media New York

About this chapter

Cite this chapter

González-Scarano, F., Bupp, K., Nathanson, N. (1996). Pathogenesis of Diseases Caused by Viruses of the Bunyavirus Genus. In: Elliott, R.M. (eds) The Bunyaviridae. The Viruses. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-1364-7_9

Download citation

  • DOI: https://doi.org/10.1007/978-1-4899-1364-7_9

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-1366-1

  • Online ISBN: 978-1-4899-1364-7

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics