Skip to main content
SpringerLink
Log in

The Exorbital Lacrimal Glands of the Rat are Tensed in Situ

  • Chapter
Lacrimal Gland, Tear Film, and Dry Eye Syndromes 2

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 438))

  • 47 Accesses

Abstract

The main lacrimal gland of rodents is a paired, extraorbital organ. Each exists subcutaneously anterior to and slightly below the ear. This study will demonstrate that this exorbital lacrimal gland exists under tension. This characteristic became manifest when we noted that the gland’s width and length diminished as its attachments were removed during excision. Were it not tensed, no such dimensional changes would have occurred as it was freed (Fig. 1).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
eBook
USD 16.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Wilkes GL, Brown LA, Wildnauer RH. The biomechanical properties of skin. Crit Rev Biomed Eng. 1973; 1: 453–495.

    CAS  Google Scholar 

  2. Tickner EG, Sacks AH. A theory for the static elastic behavior of blood vessels. Biorheology 1967; 4: 151–163.

    PubMed  CAS  Google Scholar 

  3. Semikar L, Agostini E, Toglietti A. Entita, caratteristiche e origine della depressione pleurica. Arch Sci Biol. 1957; 41: 312–325.

    Google Scholar 

  4. Calaresu FR, Tobey JC, Heidemann SR, Weaver LC. Splenic and renal sympathetic responses to stimulation of splenic receptors in cats. Am J Physiol. 1984; 247: R856–R865.

    PubMed  CAS  Google Scholar 

  5. Frame JS. Ellipsoid and spheroid. In: McGraw-Hill Encyclopedia of Science & Technology. 7th ed. New York: McGraw-Hill; 1992: 315–316.

    Google Scholar 

  6. Guyton AC, Hall JE. Textbook of Medical Physiology. 9th ed. Philadelphia: W.B. Saunders Co.; 1996: 167.

    Google Scholar 

  7. Mircheff AK, Lu CC. A map of membrane populations isolated from rat exorbital gland. Am J Physiol. 1984; 247: G651–G661.

    PubMed  CAS  Google Scholar 

  8. Goldman R, Goldman A, Green K, Jones J, Lieska N, Yang H-Y. Intermediate filaments: Possible functions as cytoskeletal connecting links between the nucleus and the cell surface. Ann N Y Acad Sci. 1985; 455: 12–17.

    Article  Google Scholar 

  9. Lorber M, Milobsky SA. Stretching of the skin in vivo: A method of influencing cell division and migration in the rat epidermis. J Invest Dermatol. 1968; 51: 395–402.

    PubMed  CAS  Google Scholar 

  10. Welling LW, Zupka MT, Welling DJ. Mechanical properties of basement membrane. News in Physiol Sci. 1995; 10: 30–35.

    Google Scholar 

  11. Zhu X, Assoian RK. Integrin-dependent activation of MAP kinase: A link to shape-dependent cell proliferation. Mol Biol Cell. 1995; 6: 273–282.

    PubMed  CAS  Google Scholar 

  12. Stein GS, Stein JL, van Wijnen AJ, Lian JB. The maturation of a cell. Am Scientist 1996; 84: 28–37.

    Google Scholar 

  13. Hamill OP, McBride DW Jr. Mechanoreceptive membrane channels. Am Scientist 1995; 83: 30–37.

    Google Scholar 

  14. Griepp EB, Robbins ES. Epithelium. In: Weiss L, ed. Cell and tissue Biology. Baltimore: Urban & Schwarzenberg; 1988: 131–142.

    Google Scholar 

  15. Yiu SC, Lambert RW, Tortoriello PJ, Mircheff AK. Secretagogue-induced redistributions of Na, K-ATPase in rat lacrimal acini. Invest Ophthalmol Vis Sci. 1991; 32: 2976–2984.

    PubMed  CAS  Google Scholar 

  16. Warren DW, Azzarolo AM, Becker L, Bjerrum K, Kaswan RL, Mircheff AK. Effects of dihydrotestosterone and prolactin on lacrimal gland function. Adv Exp Med Biol. 1994; 350: 99–104.

    Article  PubMed  CAS  Google Scholar 

  17. Sullivan DA, Sato EH. Immunology of the lacrimal gland. In: Albert DM, Jakobiec FA, eds. Principles and Practice of Ophthalmology: Basic Sciences. Philadelphia: W.B. Saunders Co.; 1994: 479–486.

    Google Scholar 

  18. Gudmundsson OG, Sullivan DA, Bloch KJ, Allansmith MR. The ocular secretory immune system of the rat. Exp Eye Res. 1985; 40: 231–238.

    Article  PubMed  CAS  Google Scholar 

  19. Mircheff AK, Gierow JP, Wood RL. Autoimmunity of the lacrimal gland. Int Ophthalmol Clin. 1994; 34: 1–18.

    Article  PubMed  CAS  Google Scholar 

  20. Whitwell J. Denervation of the lacrimal gland. Br J Ophthalmol. 1958; 42: 518–525.

    Article  PubMed  CAS  Google Scholar 

  21. Bergin DJ. Anatomy of the eyelids, lacrimal system, and orbit. In: McCord CD Jr, Tanenbaum M, Nunnery WR, eds. Oculoplastic Surgery. 3rd ed. New York: Raven Press; 1995; 73–77.

    Google Scholar 

  22. Smith B, Petrelli R. Surgical repair of prolapsed lacrimal glands. Arch Ophthalmol. 1978; 96: 113–115.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Physiology and Biophysics, Georgetown University School of Medicine, Washington, D.C., USA

    Mortimer Lorber

Authors
  1. Mortimer Lorber
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. The Schepens Eye Research Institute, Harvard Medical School, Boston, Massachusetts, USA

    David A. Sullivan  & Darlene A. Dartt  & 

  2. Louisiana State University Medical Center, New Orleans, Louisiana, USA

    Michele A. Meneray

Rights and permissions

Reprints and permissions

Copyright information

© 1998 Springer Science+Business Media New York

About this chapter

Cite this chapter

Lorber, M. (1998). The Exorbital Lacrimal Glands of the Rat are Tensed in Situ. In: Sullivan, D.A., Dartt, D.A., Meneray, M.A. (eds) Lacrimal Gland, Tear Film, and Dry Eye Syndromes 2. Advances in Experimental Medicine and Biology, vol 438. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5359-5_8

Download citation

  • DOI: https://doi.org/10.1007/978-1-4615-5359-5_8

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-7445-9

  • Online ISBN: 978-1-4615-5359-5

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation