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Hypouricemia and an Increased Clearance of Uric Acid are Observed in Liver Diseases?

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Purine and Pyrimidine Metabolism in Man VIII

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 370))

Abstract

Hypouricemia has been noted in patients with hepatocellular disease.1–5 The hypouricemia may be chiefly due to induced tubular defects but reduced production may also play a role. In the presence of liver disease either a uricemic substance (perhaps bilirubin) accumulates or a substance that enhances uric acid reabsorption is not produced. The purpose of the present paper was to determine the prevalence of low serum urate levels in liver diseases and to evaluate which degree of hepatocellular damage should be present in order to observe this metabolic alteration.

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References

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Authors and Affiliations

  1. Institute of Medical Physiopathology, University of Chieti, Italy

    A. Pelatti, C. P. Quaratino, C. D’ Amario, R. Tentarelli, G. Riario Sforza & A. Giacomello

  2. Ospedale Civile di Pescara, Italy

    A. Pelatti, C. P. Quaratino, C. D’ Amario, R. Tentarelli, G. Riario Sforza & A. Giacomello

Authors
  1. A. Pelatti
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  2. C. P. Quaratino
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  3. C. D’ Amario
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  4. R. Tentarelli
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  5. G. Riario Sforza
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  6. A. Giacomello
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Editor information

Editors and Affiliations

  1. Indiana University School of Medicine, Indianapolis, Indiana, USA

    Amrik Sahota

  2. Indiana University, Bloomington, Indiana, USA

    Milton W. Taylor

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© 1995 Springer Science+Business Media New York

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Pelatti, A., Quaratino, C.P., D’ Amario, C., Tentarelli, R., Riario Sforza, G., Giacomello, A. (1995). Hypouricemia and an Increased Clearance of Uric Acid are Observed in Liver Diseases?. In: Sahota, A., Taylor, M.W. (eds) Purine and Pyrimidine Metabolism in Man VIII. Advances in Experimental Medicine and Biology, vol 370. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-2584-4_14

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  • DOI: https://doi.org/10.1007/978-1-4615-2584-4_14

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-6105-3

  • Online ISBN: 978-1-4615-2584-4

  • eBook Packages: Springer Book Archive

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