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Squamous Cell Carcinoma

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Mohs Micrographic Surgery

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Abstract

Cutaneous squamous cell carcinoma (SCC) is the second most common cutaneous malignancy in the USA, accounting for 20% of non-melanoma skin cancers. Among Caucasians, it is the second most common cancer overall. Although the great majority of cases are cured by surgery or other treatments, deaths from SCC may be nearly as common as those from melanoma. Identification of patients at risk for untoward outcomes as well as clarity regarding appropriate staging and management, particularly of high-risk tumors, is imperative. This chapter discusses the current state of knowledge regarding the pathophysiology leading to cutaneous SCC, risk factors for its development, and the clinical spectrum of squamous dysplasia with particular attention given to high-risk and invasive disease. It provides an in-depth discussion of the available data regarding surgical and non-surgical management of cutaneous SCC, particularly of high-risk tumors.

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Authors and Affiliations

  1. Department of Dermatology, Dana Farber Cancer Institute/Brigham and Women’s Hospital, Boston, MA, USA

    Nicole R. LeBoeuf & Andrew E. Werchniak

  2. Department of Mohs Micrographic Surgery, Department of Dermatology, Dana Farber Cancer Institute/Brigham and Women’s Hospital, Boston, MA, USA

    Lorraine M. Jennings

  3. Department of Dermatologic Surgery, MOHS Micrographic Surgery Center, Brigham and Women’s Hospital, Boston, MA, USA

    Chrysalyne D. Schmults

Authors
  1. Nicole R. LeBoeuf
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  2. Lorraine M. Jennings
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  3. Andrew E. Werchniak
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  4. Chrysalyne D. Schmults
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Corresponding author

Correspondence to Nicole R. LeBoeuf .

Editor information

Editors and Affiliations

  1. Miller School of Medicine, Dept. Dermatology, University of Miami, NW. 10th Ave. 1600, Miami, 33136, Florida, USA

    Keyvan Nouri

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LeBoeuf, N.R., Jennings, L.M., Werchniak, A.E., Schmults, C.D. (2012). Squamous Cell Carcinoma. In: Nouri, K. (eds) Mohs Micrographic Surgery. Springer, London. https://doi.org/10.1007/978-1-4471-2152-7_17

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  • DOI: https://doi.org/10.1007/978-1-4471-2152-7_17

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