Skip to main content
SpringerLink
Log in

Treatment of Radiation Bowel Disease

  • Chapter
The Causation and Clinical Management of Pelvic Radiation Disease

Abstract

Radiation bowel disease (RBD) predominantly arises from radiation therapy for pelvic malignancy and both the rectum and any bowel in the Pouch of Douglas or recto-vesical pouch are particularly at risk. The greater the biological effect of any treatment regime, the greater is the possibility of achieving cure of the tumour but also the greater is the potential for producing RBD.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Aartsen EJ, Sindram IS (1988) Repair of the radiation induced rectovaginal fistulas without or with interposition of the bulbocavernosus muscle (Martius procedure). Eur J Surg Oncol 14:171–177

    PubMed  CAS  Google Scholar 

  • Ahlquist DA, Gostout CJ, Viggiano TR, Pemberton JH (1986) Laser therapy for severe radiation induced rectal bleeding. Mayo Clin Proc 61:927–931

    PubMed  CAS  Google Scholar 

  • Anselme PF, Lavery IC, Fazio VW, Jagelman DG, Weakley FL (1981) Radiation injury of the rectum. Ann Surg 194:716–724

    Article  Google Scholar 

  • Barker EM (1985) Endo-anal anastomosis without proximal stoma — a safe procedure. Br J Surg 72:S132–S133

    Article  Google Scholar 

  • Beer WH, Fan A, Halsted CH (1985) Clinical and nutritional implications of radiation enteritis. Am J Clin Nutr 41:85–91

    PubMed  CAS  Google Scholar 

  • Boronow RC (1986) Repair of the radiation-induced vaginal fistula utilizing the Martius technique. World J Surg

    Google Scholar 

  • Bourne RG, Kearsley JH, Grove WD, Roberts SJ (1983) The relationship between early and late gastrointestinal complications of radiation therapy for carcinoma of the cervix. Int J Radiat Oncol Biol Phys 9:1445–1450

    PubMed  CAS  Google Scholar 

  • Bricker EM, Johnston WD (1979) Repair of postirradiation recto-vaginal fistula and stricture. Surg Gynecol Obstet 148:499

    PubMed  CAS  Google Scholar 

  • Bricker EM, Johnston WD, Patwardham RV (1981) Repair of postirradiation damage to colorectum: a progress report. Ann Surg 193:555–564

    Article  PubMed  CAS  Google Scholar 

  • Bricker EM, Kraybill WG, Lopez MJ (1986) Functional results of postirradiation rectal reconstruction. World J Surg 10:249–258

    Article  PubMed  CAS  Google Scholar 

  • Carr ND, Pullen BR, Hasleton PS, Schofield PF (1984) Radiation bowel disease. Gut 25:448–454

    Article  PubMed  CAS  Google Scholar 

  • Cooke SAR, Wellsted MD (1986) The radiation-damaged rectum: resection with coloanal anastomosis using the endoanal technique. World J Surg 10:220–227

    Article  PubMed  CAS  Google Scholar 

  • Danjoux CE, Catton GE (1979) Delayed complications in colo-rectal carcinoma treated by combination radiotherapy and 5-fluorouracil — Eastern Cooperative Oncology Group (ECOG) Pilot Study. Int J Radiat Oncol Biol Phys 5:311–316

    Article  PubMed  CAS  Google Scholar 

  • DeCosse JJ, Rhodes RS, Wentz WB, Reagan JW, Dworken HJ, Holden WD (1969) The natural history and management of radiation induced injury of the gastrointestinal tract. Ann Surg 170:369–384

    Article  PubMed  CAS  Google Scholar 

  • Devereux DF, Kavanah MI, Feldman E et al. (1984) Small bowel exclusion from the pelvis by a polyglycolic acid mesh sling. J Surg Oncol 26:107–112

    Article  PubMed  CAS  Google Scholar 

  • Donaldson SS, Jundt S, Ricour C et al. (1975) Radiation enteritis in children: a retrospective review. Clinico-pathological correlation and dietary management. Cancer 35:1167–1181

    Article  PubMed  CAS  Google Scholar 

  • Durig M, Steenblock U, Heberer M, Harder I (1984) Prevention of radiation injuries to the small intestine. Surg Gynecol Obstet 159:162–163

    PubMed  CAS  Google Scholar 

  • France HG, Jirtle RL, Mansbach CM (1986) Intracolic WR2721 protection of the rat colon from acute radiation injury. Gastroenterology 91:644–650

    PubMed  CAS  Google Scholar 

  • Galland RB, Spencer J (1986) The surgical management of radiation enteritis. Surgery 99:133–138

    PubMed  CAS  Google Scholar 

  • Galland RB, Spencer J (1987) Natural history and surgical management of radiation enteritis. Br J Surg 74:742–747

    Article  PubMed  CAS  Google Scholar 

  • Gazet J-C (1985) Parks colo-anal pull-through anastomosis for severe complicated radiation proctitis. Dis Colon Rectum 28:110–114

    Article  PubMed  CAS  Google Scholar 

  • Gilinsky NH, Burns DG, Barbezat GO, Levin W, Myers HS, Marks IN (1983) The natural history of radiation induced proctosigmoiditis: An analysis of 88 patients. Q J Med 52:40–53

    PubMed  CAS  Google Scholar 

  • Harling H, Balslev I (1988) Long-term prognosis of patients with severe radiation enteritis. Am J Surg 155:517–519

    Article  PubMed  CAS  Google Scholar 

  • Lillemoe KD, Brigham RA, Harmon JW, Feaster M, Saunders JR, d’Avis JA (1983) Surgical management of small bowel radiation enteritis. Arch Surg 188:905–907

    Google Scholar 

  • Mäkelä J, Nevasaari K, Kairaluoma MI (1987) Surgical treatment of intestinal radiation injury. J Surg Oncol 36:93–97

    Article  PubMed  Google Scholar 

  • Martius H (1929) Sphincter und Harnröhrenplastik aus dem M. bulbocavernosus. Chirurgie 17:49

    Google Scholar 

  • Parks AG, Allen CLO, Frank JD, McPartlin JF (1978) A method of treating post-irradiation rectovaginal fistulas. Br J Surg 65:417–421

    Article  PubMed  CAS  Google Scholar 

  • Perez CA, Breaux S, Bedwinek JM et al. (1984) Radiation therapy alone in the treatment of carcinoma of the uterine cervix. II. Analysis of complications. Cancer 54:235–246

    Article  PubMed  CAS  Google Scholar 

  • Pilepich MV, Pajak T, George FW et al. (1983) Preliminary report on phase III RTOG studies of extended-field irradiation in carcinoma of the prostate. Am J Clin Oncol (CCT) 6:485

    Article  CAS  Google Scholar 

  • Rotering RH, Dixon JA, Holloway GA, McCloskey DW (1982) A comparison of the He-Ne laser and ultrasound Doppler systems in the determination of viability of ischemic canine intestine. Ann Surg 196:705–708

    Article  PubMed  Google Scholar 

  • Rubin P (1984) Late effects of chemotherapy and radiation therapy: A new hypothesis. Int J Radiat Oncol Biol Phys 10:5–34

    PubMed  CAS  Google Scholar 

  • Schofield PF, Holden D, Carr ND (1983) Bowel disease after radiotherapy. J R Soc Med 76:463–466

    PubMed  CAS  Google Scholar 

  • Schofield PF, Carr ND, Holden D (1986) The pathogenesis and treatment of radiation bowel disease. J R Soc Med 79:30–32

    PubMed  CAS  Google Scholar 

  • Sheridan WG, Lowndes RH, Young HL (1987) Tissue oxygen tension as a predictor of colonic anastomotic healing. Dis Colon Rectum 30:867–871

    Article  PubMed  CAS  Google Scholar 

  • Smith DH, DeCosse JJ (1986) Radiation damage to the small intestine. World J Surg 10:189–194

    Article  PubMed  CAS  Google Scholar 

  • Swan RW, Fowler WC, Boronow RC (1976) Surgical management of radiation injury to the small intestine. Surg Gynecol Obstet 142:325–327

    PubMed  CAS  Google Scholar 

  • Wobbes T, Verschueren RCI, Lubbers E-JC, Janssen W, Paping RHL (1984) Surgical aspects of radiation enteritis of the small bowel. Dis Colon Rectum 27:89–92

    Article  PubMed  CAS  Google Scholar 

  • Zucali R, Gardani G, Lattuada A (1987) Adjuvant irradiation after radical surgery of cancer of the rectum and rectosigmoid. Radiother Oncol 8:19–24

    Article  PubMed  CAS  Google Scholar 

Download references

Authors
  1. P. F. Schofield
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. University of Manchester, University Hospital of South Manchester, Manchester, M20 8LR, UK

    P. F. Schofield MD, FRCS (Honorary Reader in Surgery, Consultant Surgeon) (Honorary Reader in Surgery, Consultant Surgeon)

  2. University Hospital of South Manchester, Manchester, M20 8LR, UK

    E. W. Lupton MD, FRCS (Consultant Urologist) (Consultant Urologist)

Rights and permissions

Reprints and permissions

Copyright information

© 1989 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Schofield, P.F. (1989). Treatment of Radiation Bowel Disease. In: Schofield, P.F., Lupton, E.W. (eds) The Causation and Clinical Management of Pelvic Radiation Disease. Springer, London. https://doi.org/10.1007/978-1-4471-1704-9_6

Download citation

  • DOI: https://doi.org/10.1007/978-1-4471-1704-9_6

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-1706-3

  • Online ISBN: 978-1-4471-1704-9

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation