Abstract
One of the earliest indications that toxic metals could cause tissue damage as a result of an immunological reaction comes from the observations of Jadassohn (1896). Jadassohn was a dermatologist who found that patients with dermatitis, following treatment with mercuric chloride, would react directly at the site of contact with this compound. This use of a localized ‘patch test’ to indicate a state of hypersensitivity to a simple chemical agent opened up the whole field of contact sensitivity, now known to be one of the most important forms of cell-mediated immune reactions. It is accepted now that contact sensitivity to simple chemical compounds is one of the major causes of industrial morbidity in our technicological society.
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© 1971 Institute of Biology Endowment Fund
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Turk, J.L. (1971). Role of Immune Reactions in Response to Toxic Metals. In: Aldridge, W.N. (eds) A Symposium on Mechanisms of Toxicity. Biological Council. Palgrave, London. https://doi.org/10.1007/978-1-349-01085-1_7
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DOI: https://doi.org/10.1007/978-1-349-01085-1_7
Publisher Name: Palgrave, London
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