Abstract
Poisons can be classified into four types: non-specific; reactive; those with high specificity; and those requiring modification before they are toxic (lethal synthesis).
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Boyland, E., Sims, P. & Huggins, C. (1965). Nature, Lond., 207, 816
Bond, E. J., Butler, W. H., de Matteis, F. & Barnes, J. M. (1969). Br. J. indust. Med., 26, 335
Burger, P. C. & Herdson, P. B. (1966). Am. J. Path., 48, 793
Butler, W. H., Mattocks, A. R. & Barnes, J. M. (1970). J. Path., in the Press
Conney, A. H. (1967). Pharmac. Rev., 19, 317
Cremer, J. E. (1959). Br. J. indust. Med., 16, 191
Garner, R. C. & Mclean, A. E. M. (1969). Biochem. Pharmac., 18, 645
Klaassen, C. D. & Plaa, G. L. (1969). Biochem. Pharmac., 18, 2019
Mclean, A. E. M. (1967a). Biochem. Pharmac., 16, 2030
Mclean, A. E. M. (1967b). Br. J. exp. Path., 48, 632
Mclean, A. E. M. (1970). Br. J. exp. Path., 51, 317
Mclean, A. E. M. & Mclean, E. K. (1966). Biochem. J., 100, 564
Mclean, A. E. M. & Mclean, E. K. (1969). Br. med. Bull., 25, 278
Mclean, A. E. M. & Marshall, W. J. (1970). Scand. J. clin. lab. Invest., 25, supplement 113, 9
Mclean, E. K. (1970). Pharmac. Rev., in the Press
Mclean, E. K., Bras, G. & Mclean, A. E. M. (1965). Br. J. exp. Path., 46, 367
Magee, P. N. & Swann, P. F. (1969). Br. med. Bull., 25, 240
Marshall, W. J. & Mclean, A. E. M. (1969a). Biochem. J., 115, 27 P
Marshall, W. J. & Mclean, A. E. M. (1969b). Biochem. Pharmac., 18, 153
Parke, D. V. & Williams, R. T. (1969). Br. med. Bull., 25, 256
Peters, R. A. (1963). Biochemical Lesions and Lethal Synthesis, pp. 91–106. Oxford: Pergamon
Schwarzmann, V., Infante, R., Raisonnier, A. & Caroli, J. (1967). C.R. Soc. Biol., Paris, 161, 2425
Slater, T. F. (1965). Biochem. Pharmac., 14, 178
Smuckler, E. A. & Benditt, E. P. (1965). Biochemistry, 4, 671
Wergedal, J. E. & Harper, A. E. (1964). J. biol. Chem., 239, 1656
Williams, R. T. (1959). Detoxication Mechanisms, p. 450. London: Chapman & Hall
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© 1971 Institute of Biology Endowment Fund
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McLean, A.E.M. (1971). Conversion by the Liver of Inactive Molecules into Toxic Molecules. In: Aldridge, W.N. (eds) A Symposium on Mechanisms of Toxicity. Biological Council. Palgrave, London. https://doi.org/10.1007/978-1-349-01085-1_15
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DOI: https://doi.org/10.1007/978-1-349-01085-1_15
Publisher Name: Palgrave, London
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