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Comorbidity in Anxiety Disorders

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Behavioral Neurobiology of Anxiety and Its Treatment

Part of the book series: Current Topics in Behavioral Neurosciences ((CTBN,volume 2))

Abstract

Ever since Feinstein coined the term “comorbidity”, referring to the presence of any additional coexisting ailment in a patient with a particular index disease (J Chronic Dis 23:455–468, 1970), aspects of the phenomenon have been extensively studied. The aims of this chapter are: (1) to summarize the evidence of psychiatric comorbidity in anxiety disorders from adult population-based studies; (2) to present findings from the National Comorbidity Survey Replication (NCS-R); (3) to summarize evidence of psychiatric comorbidity in anxiety disorders from child and adolescent population-based samples; (4) to provide a summary of evidence on comorbidity from family and genetic studies; and (5) to examine patterns of comorbidity between anxiety disorders and medical conditions. Throughout each of these aims, implications of the comorbidity are explored, including whether these patterns reflect a need for redefining the disorders or rather an etiologic or even causal path.

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Abbreviations

NCS-R:

National Comorbidity Survey Replication

NCS:

National Comorbidity Survey

ESEMeD:

European Study of Epidemiology of Mental Disorders

NESARC:

National Epidemiologic Survey of Alcohol Related Conditions

NEMESIS:

Netherlands Mental Health Survey and Incidence Study

OHS:

Ontario Health Survey

ECA:

Epidemiological Catchment Area

ZCS:

Zurich Cohort Study

WMHI:

World Mental Health Initiative

PTSD:

Post-traumatic stress disorder

GAD:

Generalized anxiety disorder

OCD:

Obsessive compulsive disorder

ADHD:

Attention-deficit/hyperactivity disorder

TBI:

Traumatic brain injury

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Authors and Affiliations

  1. Genetic Epidemiology Research Branch, Mood and Anxiety Disorders Program, Department of Health and Human Services, National Institute of Mental Health, National Institutes of Health, 35 Convent Drive, MSC#3720, Bethesda, MD, 20892, USA

    Kathleen Ries Merikangas & Sonja Alsemgeest Swanson

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  1. Kathleen Ries Merikangas
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  2. Sonja Alsemgeest Swanson
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Correspondence to Kathleen Ries Merikangas .

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  1. Dept. Psychiatry, University of California, San Diego, Gilman Drive 9500, La Jolla, 92093-0985, USA

    Murray B. Stein

  2. Research & Development, CNS - Affective Spectrum, Johnson & Johnson Pharmaceutical, Turnhoutseweg 30, Beerse, 2340, Belgium

    Thomas Steckler

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© 2009 Springer-Verlag Berlin Heidelberg

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Merikangas, K.R., Swanson, S.A. (2009). Comorbidity in Anxiety Disorders. In: Stein, M., Steckler, T. (eds) Behavioral Neurobiology of Anxiety and Its Treatment. Current Topics in Behavioral Neurosciences, vol 2. Springer, Berlin, Heidelberg. https://doi.org/10.1007/7854_2009_32

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