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Surgical Results of Total Mesorectal Excision for Rectal Cancer in a Specialised Colorectal Unit

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Rectal Cancer Treatment

Part of the book series: Recent Results in Cancer Research ((RECENTCANCER,volume 165))

Abstract

Our aim was to review the results of total mesorectal excision (TME)in a specialised colorectal unit. Perioperative and follow-up data were prospectively collected in a computerised database. A review of all the records was made. The morbidity rate was about 14%, and was higher in patients with coloplasty due to a higher anastomotic leak rate. The local recurrence rate was 2%, the distant metastasis rate was 11%, and both local and distant metastasis occurred in 4%. About 95% of recurrence occurred within 3 years. There was better bowel function in patients with a colonic J-pouch in the first 2 years after surgery, but the advantage disappeared thereafter. There were no differences in function between descending and sigmoid colonic J-pouches. TME in a specialised colorectal unit has lowmorbidity and mortality. Our procedure of choice is that of a sigmoid colon J-pouch anal anastomosis.

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References

  1. Heald RJ, Husband EM, Ryall RD (1982) The mesorectum in rectal cancer surgery-the clue to pelvic recurrence? Br J Surg 69(10):613–616

    PubMed  Google Scholar 

  2. Nelson H, Petrelli N, Carlin A, Couture J, Fleshman J, Guillem J et al (2001) Guidelines 2000 for colon and rectal cancer surgery. J Natl Cancer Inst 93(8):583–596

    Article  PubMed  Google Scholar 

  3. Becouarn Y, Blanc-Vincent MP, Ducreux M, Lasser P, Dubois JB, Giovannini M et al (2001) Cancer of the rectum. Br J Cancer 84Suppl 2:69–73

    Article  PubMed  Google Scholar 

  4. Wiig JN, Carlsen E, Soreide O (1998) Mesorectal excision for rectal cancer: a view from Europe. Semin Surg Oncol 15(2):78–86

    Article  PubMed  Google Scholar 

  5. Kapiteijn E, Marijnen CA, Nagtegaal ID, Putter H, Steup WH, Wiggers T et al (2001) Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer. N Engl J Med 345(9):638–46

    PubMed  Google Scholar 

  6. MacFarlane JK, Ryall RD, Heald RJ (1993) Mesorectal excision for rectal cancer. Lancet 341(8843):457–460

    Article  PubMed  Google Scholar 

  7. Gunderson LL, Sosin H (1974) Areas of failure found at reoperation (second or symptomatic look) following “curative surgery” for adenocarcinoma of the rectum. Clinicopathologic correlation and implications for adjuvant therapy. Cancer 34(4):1278–1292

    PubMed  Google Scholar 

  8. Heah SM, Seow-Choen F, Eu KW, Ho YH, Tang CL (2002) Prospective, randomized trial comparing sigmoid vs. descending colonic J-pouch after total rectal excision. Dis Colon Rectum 45(3):322–328

    Article  PubMed  Google Scholar 

  9. Ho YH, Brown S, Heah SM, Tsang C, Seow-Choen F, Eu KW et al (2002) Comparisonof J-pouch and coloplasty pouch for low rectal cancers: a randomized, controlled trial investigating functional results and comparative anastomotic leak rates. Ann Surg 236(1):49–55

    Article  PubMed  Google Scholar 

  10. Pimentel JM, Duarte A, Gregorio C, Souto P, Patricio J (2003) Transverse coloplasty pouch and colonic J-pouch for rectal cancer-a comparative study. Colorectal Dis (5):465–470

    Article  PubMed  Google Scholar 

  11. Kraemer M, Wiratkapun S, Seow-Choen F, Ho YH, Eu KW, Nyam D (2001) Stratifying risk factors for follow-up: a comparison of recurrent and nonrecurrent colorectal cancer. Dis Colon Rectum 44(6):815–821

    PubMed  Google Scholar 

  12. Galandiuk S, Wieand HS, Moertel CG, Cha SS, Fitzgibbons RJ, Jr., Pemberton JH et al (1992) Patterns of recurrence after curative resection of carcinoma of the colon and rectum. Surg Gynecol Obstet 174(1):27–32

    PubMed  Google Scholar 

  13. Phillips RK, Hittinger R, Blesovsky L, Fry JS, Fielding LP (1984) Local recurrence following ‘curative’ surgery for large bowel cancer: I. The overall picture. Br J Surg 71(1):12–16

    PubMed  Google Scholar 

  14. Adloff M, Arnaud JP, Schloegel M, Thibaud D (1985) Factors influencing local recurrence after abdominoperineal resection for cancer of the rectum. Dis Colon Rectum 28(6):413–415

    PubMed  Google Scholar 

  15. Obrand DI, Gordon PH (1997) Incidence and patterns of recurrence following curative resection for colorectal carcinoma. Dis Colon Rectum 40(1):15–24

    Article  PubMed  Google Scholar 

  16. Halvorsen TB, Seim E (1987) Tumour site: a prognostic factor in colorectal cancer? A multivariate analysis. Scand J Gastroenterol 22(1):124–128

    PubMed  Google Scholar 

  17. Pilipshen SJ, Heilweil M, Quan SH, Sternberg SS, Enker WE (1984) Patterns of pelvic recurrence following definitive resections of rectal cancer. Cancer 53(6):1354–1362

    PubMed  Google Scholar 

  18. Takahashi T, Kato T, Kodaira S, Koyama Y, Sakabe T, Tominaga T et al (1996) Prognostic factors of colorectal cancer. Results of multivariate analysis of curative resection cases with or without adjuvant chemotherapy. Am J Clin Oncol 19(4):408–415

    Article  PubMed  Google Scholar 

  19. Kagda FH, Nyam DC, Ho YH, Eu KW, Leong AF, Seow-Choen F (1999) Surgerymay be curative for patients with a localized perforation of rectal carcinoma. Br J Surg 86(11):1448–1450

    Article  PubMed  Google Scholar 

  20. Seow-Choen F (2002) Adjuvant therapy for rectal cancer cannot be based on the results of other surgeons. Br J Surg 89(8):946–947

    Article  PubMed  Google Scholar 

  21. Hermanek P, Hohenberger W, Klimpfinger M, Kockerling F, Papadopoulos T (2003) The pathological assessment of mesorectal excision: implications for further treatment and quality management. Int J Colorectal Dis 18(4):335–341

    PubMed  Google Scholar 

  22. Seow-Choen F, Goh HS (1995) Prospective randomized trial comparing J colonic pouch-anal anastomosis and straight coloanal reconstruction. Br J Surg 82(5):608–610

    Google Scholar 

  23. Ho YH, Tan M, Seow-Choen F (1996) Prospective randomized controlled study of clinical function and anorectal physiology after low anterior resection: comparison of straight and colonic J pouch anastomoses. Br J Surg 83(7):978–980

    PubMed  Google Scholar 

  24. Hallbook O, Pahlman L, Krog M, Wexner SD, Sjodahl R (1996) Randomized comparison of straight and colonic J pouch anastomosis after low anterior resection. Ann Surg 224(1):58–65

    Article  PubMed  Google Scholar 

  25. Lazorthes F, Chiotasso P, Gamagami RA, Istvan G, Chevreau P (1997) Late clinical outcome in a randomized prospective comparison of colonic J pouch and straight coloanal anastomosis. Br J Surg 84(10):1449–1451

    Article  PubMed  Google Scholar 

  26. Ho YH, Seow-Choen F, Tan M (2001) Colonic J-pouch function at six months versus straight coloanal anastomosis at two years: randomized controlled trial. World J Surg 25(7):876–881

    Article  PubMed  Google Scholar 

  27. Williams N, Seow-Choen F (1998) Physiological and functional outcome following ultra-low anterior resection with colon pouch-anal anastomosis. Br J Surg 85(8):1029–1035

    Article  PubMed  Google Scholar 

  28. Ho YH, Tan M, Leong AF, Seow-Choen F (2000) Ambulatory manometry in patients with colonic J-pouch and straight coloanal anastomoses: randomized, controlled trial. Dis Colon Rectum 43(6):793–799

    PubMed  Google Scholar 

  29. Maurer CA, Z'Graggen K, Zimmermann W, Hani HJ, Mettler D, Buchler MW (1999) Experimental study of neorectal physiology after formation of a transverse coloplasty pouch. Br J Surg 86(11):1451–1458

    Article  PubMed  Google Scholar 

  30. Z'Graggen K, Maurer CA, Mettler D, Stoupis C, Wildi S, Buchler MW (1999) A novel colon pouch and its comparison with a straight coloanal and colon J-pouch-anal anastomosis: preliminary results in pigs. Surgery 125(1):105–112

    PubMed  Google Scholar 

  31. Mantyh CR, Hull TL, Fazio VW (2001) Coloplasty in low colorectal anastomosis: manometric and functional comparisonwith straight and colonic J-pouch anastomosis. Dis Colon Rectum 44(1):37–42

    PubMed  Google Scholar 

  32. Fazio VW, Mantyh CR, Hull TL (2000) Colonic “coloplasty”: novel technique to enhance low colorectal or coloanal anastomosis. Dis Colon Rectum 43(10):1448–1450

    PubMed  Google Scholar 

  33. Furst A, Suttner S, Agha A, Beham A, Jauch KW (2003) Colonic J-pouch vs. coloplasty following resection of distal rectal cancer: early results of a prospective, randomized, pilot study. Dis Colon Rectum 46(9):1161–1166

    Article  PubMed  Google Scholar 

  34. Quah HM, Jayne DG, Eu KW, Seow-Choen F (2002) Bladder and sexual dysfunction following laparoscopically assisted and conventional open mesorectal resection for cancer. Br J Surg 89(12):1551–1556

    Article  PubMed  Google Scholar 

  35. Barry MJ, Fowler FJ, Jr., O'Leary MP, Bruskewitz RC, Holtgrewe HL, Mebust WK et al (1992) The American Urological Association symptom index for benign prostatic hyperplasia. The Measurement Committee of the American Urological Association. J Urol 148(5):1549–1557; discussion 1564

    PubMed  Google Scholar 

  36. Cosimelli M, Mannella E, Giannarelli D, Casaldi V, Wappner G, Cavaliere F et al (1994)Nervesparing surgery in 302 resectable rectosigmoid cancer patients: genitourinary morbidity and 10-year survival. Dis Colon Rectum 37(2 Suppl):42–46

    Article  PubMed  Google Scholar 

  37. Cunsolo A, Bragaglia RB, Manara G, Poggioli G, Gozzetti G (1990) Urogenital dysfunction after abdominoperineal resectionfor carcinomaof the rectum. Dis Colon Rectum 33(11):918–922

    Article  PubMed  Google Scholar 

  38. Danzi M, Ferulano GP, Abate S, Califano G (1983) Male sexual function after abdominoperineal resection for rectal cancer. Dis Colon Rectum 26(10):665–668

    PubMed  Google Scholar 

  39. Havenga K, Enker WE, McDermott K, Cohen AM, Minsky BD, Guillem J (1996) Male and female sexual and urinary function after total mesorectal excision with autonomic nerve preservation for carcinoma of the rectum. J Am Coll Surg 182(6):495–502

    PubMed  Google Scholar 

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© 2005 Springer-Verlag Berlin Heidelberg

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Ho, K., Seow-Choen, F. (2005). Surgical Results of Total Mesorectal Excision for Rectal Cancer in a Specialised Colorectal Unit. In: Büchler, M.W., Weitz, J., Ulrich, B., Heald, R.J. (eds) Rectal Cancer Treatment. Recent Results in Cancer Research, vol 165. Springer, Berlin, Heidelberg. https://doi.org/10.1007/3-540-27449-9_12

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  • DOI: https://doi.org/10.1007/3-540-27449-9_12

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-540-23341-1

  • Online ISBN: 978-3-540-27449-0

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