Abstract
Anti-NMDA receptor encephalitis is an acute form of brain inflammation that is potentially lethal but has a high probability for recovery with treatment. Although the clinical picture of anti-NMDAR encephalitis is usually recognizable due to its relatively well-known symptoms, the disorder can sometimes present itself in an unpredictable and atypical way. In this case report, we wish to present the influence of different delay times prior to the establishment of diagnosis. Thus, our first patient was diagnosed with anti-NMDAR encephalitis 4 years after the initial symptoms, the second one after 8 years, and the third one after 13 months. The outcomes of the three presented patients indicate the importance of being aware of many clinical presentations of this disorder, as its early diagnosis greatly affects the outcome and may reduce permanent damage, especially in cognitive functions.
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VS and ZPG prepared the case report. ZPG, SN, and VS are consultant neurologist responsible for the care of the patients. MS has been consulted as a specialist in infectious diseases and intensive medicine. DB and FD are responsible for the reference managing and preparing the text for submission.
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Sulentic, V., Petelin Gadze, Z., Derke, F. et al. The effect of delayed anti-NMDAR encephalitis recognition on disease outcome. J. Neurovirol. 24, 638–641 (2018). https://doi.org/10.1007/s13365-018-0648-y
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DOI: https://doi.org/10.1007/s13365-018-0648-y