Abstract
Diagnostic (mapping) and therapeutic (ablation, pacing) advances have provided insightinto atrial depolarization processes and new developments in P wave analysis. Information about interatrial pathwaysis important to the understanding of interatrial conduction delay. A standardized method for P wave analysis isnecessary for the development of a clinical role for management of patients with paroxysmal atrial fibrillationusing signal-averaged P wave analysis and P wave dispersion. Algorithms for predicting localization of ectopic Pwaves may facilitate catheter ablation. P wave changes due to pacing at different atrial sites may be useful forpermanent pacing for prevention of atrial fibrillation. Introduction of these developments into clinical practiceshould allow better prevention and treatment of atrial arrhythmias and could have considerable impact in view oftheir high frequency especially in the older population.
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Chauvin M, Shah DC, Häissaguerre M, Marcellin L, Brechenmacher C. The anatomic basis of connections between the coronary sinus musculature and the left atrium in humans. Circulation 2000;101:647–652.
Kasai A, Anselme F, Saoudi N. Myocardial connections between left atrial myocardium and coronary sinus musculature in man. J Cardiovasc Electrophysiol2001;12:981–985.
Sanchez-Quintana D, Davies DW, Yen Ho S, Oslizlok P, Anderson RH. Architecture of the atrial musculature in and around the triangle of Koch: Its potential relevance to atrioventricular nodal reentry. J Cardiovasc Electrophysiol 1997;8:1396–1407.
Sun H, Velipasaoglu EO, Wu DE, Kopelen HA, Zoghbi WA, Spencer III WH, Khoury DS. Simultaneous multisite mapping of the right and the left atrial septum in the canine intact beating heart. Circulation 1999;100:312–319.
Canavan TE, Schuessler RB, Boineau JP, Corr PB, Cain ME, Cox JL. Computerized global electrophysiological mapping of the atrium in patients with Wolff-Parkinson-White syndrome. Ann Thorac Surg 1988;46:223–231.
Boineau JP, Canavan TE, Schuessler RB, Cain ME, Corr PB, Cox JL. Demonstration of a a widely distributed atrial pacemaker complex in the human heart. Circulation 1988;6:1221–1237.
Pennington JC, Padder FA, Callans DJ, Gottlieb CD, Marchlinski FE. Right atrial activation and its potential contribution to surface P-wave. Circulation1998;98:I-25.
Waldo Al, Bush HL, Gelband H, Zorn GL Jr, Vitikainen KJ, Hoffman BF. Effects on the canine P wave of discrete lesions in the specialized atrial tracts. Circ Res 1971;29(5):452–467.
Bayés de Luna A, Guindo J, Vinolas X, Martinez-Rubio A, Bay´es-Genis A. Third degree (advanced) interatrial block. G Ital Cardiol 1998;28(Suppl 1): 26–29.
Bagliani G, Meniconi L, Raggi F, Corea L. Left origin of the atrial esophageal signal as recorded in the pacing site. Pacing Clin Electrophysiol 1998;21 (1 Pt 1):18–24.
Jairath UC, Spodick DH. Exceptional prevalence of interatrial block in a general hospital population. Clin Cardiol 2001;24(8):548–550.
Sobrino JA, del Rio A, Maté I, Sobrino N. Bradycardia dependent interatrial block with retrograde left atrial activation. Brit Heart J 1977;39:222–225.
Goyal SB, Spodick DH. Electromechanical dysfunction of the left atrium associated with interatrial block. Am Heart J 2001;142:823–827.
Ramsaran EK, Spodick DH. Electromechanical delay in the left atrium as a consequence of interatrial block. Am J Cardiol 1996;77(12):1132–1134.
Wish M, Fletcher RD, Gottdiener MD, Cohen AI. Importance of left atrial timing in the programming of dual chamber pacemakers. Am J Cardiol1987;60:566–571.
Camous JP, Raybaud F, Dolisi C, Schenowitz A, Varenne A, Baudouy M. Interatrial conduction in patients undergoing AV stimulation: Effects of increasing right atrial stimulation rate. Pacing Clin Electrophysiol 1993;16:2082–2086.
Ausubel K, Klementowicz P, Furman S. Interatrial conduction during cardiac pacing. Pacing Clin Electrophysiol1986;9:1026–1031.
Dilaveris P, Batchvarov V, Gialafos J, Malik M. Comparison of different methods for manual P wave duration measurements in 12–lead electrocardiograms. Pacing Clin Electrophysiol 1999;22: 1532–1538.
Dilaveris PE, Gialafos JE. P-wave dispersion: A novel predictor of paroxysmal atrial fibrillation. Ann Noninvasive Electrocardiol 2001;6(2): 159–165.
Michelucci A, Padeletti L, Porciani MC, Gensini GF. P-wave signal-averaging. Cardiac Electrophysiol Rev 1997;1(3):325–332.
Michelucci A, Padeletti L, Colella A, Porciani MC, Gensini GF. Advances in P wave signal-averaging. Cardiac Electrophysiol Rev 1999;3(4):257–260.
Babaev AA, Vloka ME, Sadurski R, Steinberg JS. Influence of age on atrial activation as measured by the P-wave signal-averaged electrocardiogram. Am J Cardiol 2000;86:692–695.
Michelucci A, Padeletti L, Chelucci A, Mezzani A, Porciani MC, Caruso F, Lebrun E, Bacci F, Martelli M, Gensini GF. Influence of age, lead axis, frequency of arrhythmic episodes, and atrial dimensions on P wave-triggered signal-averaged ECG in patients with lone paroxysmal atrial fibrillation. Pacing Clin Electrophysiol1996;19:758–767.
Ndrepepa G, Zrenner B, Deisenhofer I, Karch M, Schneider M, Schreieck J, Schmitt C. Relationship between surface electrocardiogram characteristics and endocardial activation sequence in patients with typical atrial flutter. Z Kardiol 2000;89(6): 527–537.
T¨ukek T, Akkaya V, Demirel S, Sozen AB, Kudat H, Atilgan D, Ozcan M, Guven O, Korkut F. Effect of Valsalva maneuver on surface electrocardiographic P-wave dispersion in paroxysmal atrial fibrillation. Am J Cardiol 2000;85;896–899.
Özmen F, Atalar E, Aytemir K, Özer N, Açil T, Övünc¸ K, Aksöyek S, Kes S. Effect of ballooninduced acute ischaemia on P wave dispersion during percutaneous transluminal coronary angioplasty. Europace 2001;3:299–303.
MacLean WHA, Karp RB, Kouchoukos NT, James TN, Waldo AL. P waves during ectopic atrial rhythms in man. A study utilizing atrial pacing with fixed electrodes. Circulation 1975;52: 426–434.
Waldo AL, Vitikainen KJ, Kaiser GA, Malm JR, Hoffman BF. The P wave and PR interval. Effects of the site of origin of atrial depolarization. Circulation1970;42:653–671.
Tse HF, Lau CP, Lee KL, Pelosi F, Oral H, Knight BP, Strickberger SA, Morady F. Pwave polarity during pacing in pulmonary veins. J Int Card Electrophysiol2001;5(2):167–172.
Tada H, Nogami A, Naito S, Suguta M, Nakatsugawa M, Horie Y, Tomita T, Hoshizaki H, Oshima S, Taniguchi K. Simple electrocardiographic criteria for identifying the site of origin of focal right atrial tachycardia. Pacing Clin Electrophysiol 1998;21(11, Part 2):2431–2439.
Morton JB, Sanders P, Das A, Vohra JK, Sparks PB, Kalman JM. Focal atrial tachycardia arising from the tricuspid annulus: Electrophysiologic and electrocardiographic characteristics. J Cardiovasc Electrophysiol 2001;12:653–659.
Tang CW, Scheinman MM, Van Hare GF, Epstein LM, Fitzpatrick AP, Lee RJ, Lesh MD. Use of P wave configuration during atrial tachycardia to predict site of origin. J Am Coll Cardiol 1995;26: 1315–1324.
SippensGroenewegen A, Peeters HAP, Jessurun ER, Linnenbank AC, Robles de Medina EO, Lesh MD, van Hemel NM. Body surface mapping during pacing at multiple sites in the human atrium. P wave morphology of ectopic right atrial activation. Circulation 1998;97:369–380.
Hao SC, Okin PM, Kligfield P. Spontaneous interpolated atrial premature complex detected by 12–lead ambulatory monitoring. Am J Cardiol2001;88:199–200.
Roithinger FX, Abou-Harb M, Pachinger O, Hintringer F. The effect of the atrial pacing site on the total atrial activation time. Pacing Clin Electrophysiol2001;24:316–322.
Bennet DH. Comparison of the acute effects of pacing the atrial septum, right atrial appendage, coronary sinus os, and the latter two sites simultaneously on the duration of atrial activation. Heart2000;84:193–196.
Bailin SJ, Adler S, Giudici M. Prevention of chronic atrial fibrillation by pacing in the region of Bachmann's bundle: Results of a multicenter randomized trial. J Cardiovasc Electrophysiol2001;12:912–917.
Padeletti L, Porciani MC, Michelucci A, Colella A, Ticci P, Vena S, Costoli A, Ciapetti C, Pieragnoli P, Gensini GF. Interatrial septum pacing: A new approach to prevent recurrent atrial fibrillation. J Interv Card Electrophysiol 1999;3:35–43.
D'Allonnes GR, Pavin D, Leclercq C, Ecke JE, Jauvert G, Mabo P, Daubert JC. Long-term effects of biatrial synchronous pacing to prevent drug-refractory atrial tachyarrhythmia: A nine year experience. J Cardiovasc Electrophysiol2000;11(10):1081–1091.
Delfaut P, Saksena S, Prakash A, Krol RB. Longterm outcome of patients with drug-refractory atrial flutter and fibrillation after single-and dualsite right atrial pacing for arrhythmia prevention. J Am Coll Cardiol 1998;32:1900–1908.
Daubert C, Gras D, Berder V, Leclercq C, Mabo P. Permanent atrial resynchronization by synchronous bi-atrial pacing in the preventive treatment of atrial flutter associated with high degree interatrial block. Arch Mal Coeur Vaiss1994;87(Suppl): 1535–1546.
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Michelucci, A., Bagliani, G., Colella, A. et al. P Wave Assessment: State of the Art Update. Card Electrophysiol Rev 6, 215–220 (2002). https://doi.org/10.1023/A:1016368723033
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DOI: https://doi.org/10.1023/A:1016368723033