Zusammenfassung
Die Palliative Sedierung als therapeutische Handlungsoption in anderweitig refraktären Behandlungssituationen wird in der Öffentlichkeit und in Fachkreisen in ihrer klinischen Wertigkeit grundsätzlich akzeptiert und weitgehend positiv konnotiert. Im Widerspruch dazu fallen sowohl die Quantität der empirischen Forschung als auch die Intensität der ethischen und klinischen Diskussion ins Auge, mit der konzeptuelle als auch durchführungsbezogene Aspekte der Palliativen Sedierung beschrieben und kontrovers erörtert werden. Anstatt eines distinkten Behandlungskonzeptes stellt sich hier eher ein komplexes Spektrum verschiedener (und ggf. ethisch verschieden zu bewertender) Vorgehensweisen dar. Die folgende Übersichtsarbeit fasst anhand der aktuellen Literatur zusammen, welche Aspekte im Kontext der Palliativen Sedierung als problematisch bewertet werden.
Abstract
Definition of the problem Palliative sedation as a therapeutic option in otherwise refractory clinical situations has been broadly accepted and appreciated by general society and by health care professionals. Arguments However, intense empirical research activities have been undertaken and there is an ongoing controversial ethical and clinical debate on conceptual and procedural aspects of palliative sedation. Conclusion This review discusses the current literature and the aspects on palliative sedation that are considered problematic, and finds a complex spectrum of different modes of conduct (subject to moral reasoning and different moral judgments), rather than a distinct conceptual entity.
Notes
Bundesgerichtshof (BGH) AZ XII ZB 2/03, N Jurist Wochenschr 56:1588–1594
http://www.eapc-2013.org/Final_Program.html, zugegriffen: 15. Dez. 2013
BGH AZ XII ZB 2/03, N Jurist Wochenschr 56:1588–1594
www.who.org; zugegriffen: 15. Feb. 2013
Literatur
Alonso-Babarro A, Varela-Cerdeira M, Torres-Vigil I, Rodríguez-Barrientos R, Bruera E (2010) At home palliative sedation for end-of-life cancer patients. Pall Med 24:486–492
Alt-Epping B, Nauck F (2012) Der Wunsch des Patienten – ein eigenständiger normativer Faktor in der klinischen Therapieentscheidung? Ethik Med 24:19–28
Alt-Epping B, Sitte T, Nauck F, Radbruch L (2010) Sedierung in der Palliativmedizin – Leitlinie für den Einsatz sedierender Maßnahmen in der Palliativversorgung. Z Palliativmed 11:112–122
Anonymus (2010) Palliativmedizin im interkulturellen Kontext. Ethik Med 22:49–50
Anquinet L, Raus K, Sterckx S, Smets T, Deliens L, Rietjens J (2013) Similarities and differences between continuous sedation until death and euthanasia – professional caregivers’ attitudes and experiences: a focus group study. Palliat Med 27:553–561
Baumann A, Claudot F, Audibert G, Mertes PM, Puybasset L (2011) The ethical and legal aspects of palliative sedation in severely brain-injured patients: a French perspective. Philos Ethics Humanit Med 6:4
Beauverd M, Bernard M, Currat T, Ducret S, Foley RA, Borasio GD, Blondeau D, Dumont S (2013) French Swiss physicians’ attitude toward palliative sedation: influence of prognosis and type of suffering. Palliat Support Care. doi:10.1017/S1478951513000278
Blondeau D, Roy L, Dumont S, Godin G, Martineau I (2005) Physicians’ and pharmacists’ attitudes toward the use of sedation at the end of life: influence of prognosis and type of suffering. J Palliat Care 21:238–245
Brinkkemper T, Klinkenberg M, Deliens L, Eliel M, Rietjens JA, Zuurmond WW, Perez RS (2011) Palliative sedation at home in the Netherlands: a nationwide survey among nurses. J Adv Nurs 67:1719–1728
Broeckaert B (2011) Palliative sedation, physician-assisted suicide, and euthanasia: “Same, same but different”? Am J Bioeth 11:62–64
Bundesärztekammer (2011) Grundsätze der Bundesärztekammer zur ärztlichen Sterbebegleitung. Dtsch Ärztebl 107:A 877–882
Carr MF, Mohr GJ (2008) Palliative sedation as part of a continuum of palliative care. J Pall Med 11:76–81
Cassell EJ, Rich BA (2010) Intractable end-of-life suffering and the ethics of palliative sedation. Pain Med 11:435–438
Cellarius V (2008) Terminal sedation and the imminence condition. J Med Ethics 34:69–72
Cellarius V (2011) ‘Early terminal sedation’ is a distinct entity. Bioethics 25:46–54
Cherny NI, Radbruch L (2009) EAPC recommended framework for the use of sedation in palliative care. Pall Med 23:581–593
Deutsche Hospiz Stiftung. Meinungen zum Sterben. Emnid-Umfrage (2001) https://www.stiftung-patientenschutz.de/uploads/files/pdf/stellungnahmen/08.pdf. Zugegriffen: 10. Dez. 2013
D’Haene I, Pasman HR, Deliens L, Bilsen J, Mortier F, Vander Stichele R (2010) End-of-life care policies in Flemish residential care facilities accommodating persons with intellectual disabilities. J Intellect Disabil Res 54:1067–1077
Douglas CD, Kerridge IH, Ankeny RA (2013) Narratives of ‘terminal sedation’, and the importance of the intention-foresight distinction in palliative care practice. Bioethics 27:1–11
Feen E (2011) Continuous deep sedation: consistent with physician’s role as healer. Am J Bioeth 6:49–51
Gielen J, Gupta H, Rajvanshi A, Bhatnagar S, Mishra S, Chaturvedi AK, den Branden SV, Broeckaert B (2011) The attitudes of Indian palliative-care nurses and physicians to pain control and palliative sedation. Indian J Palliat Care 17:33–41
de Graeff A, Dean M (2007) Palliative sedation therapy in the last weeks of life: a literature review and recommendations for standards. J Palliat Med 10:67–85
Halifax J (2008) Being with dying. Cultivating compassion and fearlessness in the presence of death. Shambhala Publishers, Boston
Hasselaar J, Reuzel R, van den Muijsenbergh M, Koopmans R, Leget C, Crul B, Vissers K (2008) Dealing with delicate issues in continuous deep sedation. Varying practices among Dutch medical specialists, general practitioners, and nursing home physicians. Arch Intern Med 168:537–543
Hasselaar JG (2008) Palliative sedation until death: an approach from Kant’s ethics of virtue. Theor Med Bioeth 29:387–396
Jansen LA, Sulmasy DP (2002) Sedation, alimentation, hydration, and equivocation: careful conversation about care at the end of life. Ann Intern Med 136:845–849
Jaspers B (2011) Ethische Entscheidungen am Lebensende bei Palliativpatienten in Deutschland – Eine prospektive Untersuchung anhand von Daten aus der Kerndokumentation 2005 und 2006. Schaker, Aachen
Jaspers B, Nauck F, Lindena G, Elsner F, Ostgathe C, Radbruch L (2012) Palliative sedation in Germany: how much do we know. A prospective survey. J Palliat Med 15:672–680
Juth N, Lindblad A, Linöe N, Sjöstrand M, Helgesson G (2010) European Association for Palliative Care (EAPC) framework for palliative sedation: an ethical discussion. BMC Palliat Care 9:20
Kaldjian LC, Jekel JF, Bernene JL, Rosenthal GE, Vaughan-Sarrazin M, Duffy TP (2004) Internists’ attitudes towards terminal sedation in end of life care. J Med Ethics 30:499–503
Kovacs J, Casey N, Weixler D (2008) Palliative Sedierungstherapie in der Pädiatrie. Wien Med Wochenschr 158(23–24):659–663
LiPuma S (2013) Continuous sedation until death as physician-assisted suicide/euthanasia: a conceptual analysis. J Med Philos 38:190–204
LiPuma SH (2011) The lacking of moral equivalency for continuous sedation and PAS. Am J Bioeth 11:48–49
Materstvedt LJ, Clark D, Ellershaw J, Førde R, Boeck Gravgaard AM, Müller-Busch HC, Porta i Sales J, Rapin CH (2003) Euthanasia and physician-assisted suicide: a view from an EAPC Ethics Task Force. Palliat Med 17:97–101
Müller-Busch HC (2008) Leitlinie zum Einsatz einer palliativen Sedierung am Lebensende. In: Deutsche Krebsgesellschaft (Hrsg) Kurzgefasste interdisziplinäre Leitlinien 2008. W. Zuckschwerdt Verlag, München, S 340–343
Müller-Busch HC, Andres I, Jehser T (2003) Sedation in palliative care – a critical analysis of 7 years experience. BMC Palliat Care 2:2
Müller-Busch HC, Oduncu FS, Woskanjan S, Klaschik E (2004) Attitudes on euthanasia, physicianassisted suicide and terminal sedation – A survey of the members of the German Association for Palliative Medicine. Med Health Care Philos 7:333–339
Müller-Busch HC, Radbruch L, Strasser F et al (2006) Empfehlungen zur palliativen Sedierung. Arbeitsergebnisse einer internationalen Expertengruppe. Dtsch Med Wochenschr 131:2733–2736
Nagel E (2012) contra. Dtsch Ärztebl 109:1696
Neitzke G (2008) Unterscheidung zwischen medizinischer und ärztlicher Indikation. In: Charbonnier R, Dörner K, Simon S (Hrsg) Medizinische Indikation und Patientenwille. Schattauer, Stuttgart, S 53–66
Neitzke G, Oehmichen F, Schliep HJ, Wördehoff D (2010) Sedierung am Lebensende. Empfehlungen der AG Ethik am Lebensende in der Akademie für Ethik in der Medizin (AEM). Ethik Med 22:139–147
Pousset G, Bilsen J, Cohen J, Mortier F, Deliens L (2011) Continuous deep sedation at the end of life of children in Flanders, Belgium. J Pain Symptom Manage 41:449–455
Powers CL, McLean PC (2011) The community speaks: continuous deep sedation as caregiving versus physician-assisted suicide as killing. Am J Bioeth 11:65–66
Putman MS, Yoon JD, Rasinski KA, Curlin FA (2013) Intentional sedation to unconsciousness at the end of life: findings from a national physician survey. J Pain Symptom Manage 46:326–334
Quill TE, Lo B, Brock DW, Meisel A (2009) Last-resort options for palliative sedation. Ann Intern Med 151:421–424
Rady MY, Verheijde JL (2010) Continuous deep sedation until death: palliation or physician-assisted death? Am J Hosp Palliat Care 27:205–214
Raspe H (1995) Ethische Aspekte der Indikation. In: Toellner R, Wiesing U (Hrsg) Wissen – Handeln – Ethik. Strukturen ärztlichen Handelns und ihre ethische Relevanz. G. Fischer, Stuttgart, S 21–36
Rietjens JA, van der Heide A, Vrakking AM, Onwuteaka-Philipsen BD, van der Maas PJ, van der Wal G (2004) Physician reports of terminal sedation without hydration or nutrition for patients nearing death in the Netherlands. Ann Intern Med 141:178–185
Rinpoche S (2004) Das tibetische Buch vom Leben und vom Sterben – Ein Schlüssel zum tieferen Verständnis von Leben und Tod. Fischer, Frankfurt
Rousseau PC (2000) Palliative sedation: a brief review of ethical validity and clinical experience. Mayo Clinic Proc 75:1064–1069
Rousseau PC (2001) Existential suffering and palliative sedation: a brief commentary with a proposal for clinical guidelines. Am J Hosp Palliat Care 18:151–153
Russel JA, Williams MA, Drogan O (2010) Sedation for the imminently dying. Survey results from the AAN Ethics Section. Neurology 74:1303–1309
Sahm S (2008) Autonomie, ärztliche Indikation und Entscheidungsfindung. In: Charbonnier R, Dörner K, Simon S (Hrsg) Medizinische Indikation und Patientenwille. Schattauer, Stuttgart, S 121–131
Schippinger W, Weixler D, Müller-Busch HC (2010) Palliative Sedierung zur Symptomkontrolle massiver Dyspnoe. Wien Med Wochenschr 160(13–14):338–342
Schildmann E, Schildmann J (2014) Palliative sedation therapy: a systematic literature review and critical appraisal of available guidance on indication and decision making. J Pall Med 17(5). doi:10.1089/jpm.2013.0511
Seale C (2010) Continuous deep sedation in medical practice: a descriptive study. J Pain Symptom Manage 39:44–53
Seymour J, Rietjens J, Brown J, van der Heide A, Sterckx S, Deliens L; UNBIASED study team (2011) The perspectives of clinical staff and bereaved informal care-givers on the use of continuous sedation until death for cancer patients: the study protocol of the UNBIASED study. BMC Palliat Care 10:5
Simon A, Kar M, Hinz J, Beck D (2007) Attitudes toward terminal sedation: an empirical survey among experts in the field of medical ethics. BMC Palliat Care 6:4
Smets T, Cohen J, Bilsen J, Van Wesemael Y, Rurup ML, Deliens L (2012) The labelling and reporting of euthanasia by Belgian physicians: a study of hypothetical cases. Eur J Public Health 22:19–26
Steinhauser KE, Christakis NA, Clipp EC, McNeilly M, McIntyre L, Tulsky JA (2000) Factors considered important at the end of life by patients, family, physicians, and other care providers. JAMA 284:2476–2482
Weichselbaumer E, Weixler D (2013) Palliative sedation for psycho-existential suffering. Wien Med Wochenschr Oct 25. doi:10.1007/s10354-013-0246-9
Winkler E (2010) Ist ein Therapieverzicht gegen den Willen des Patienten ethisch begründbar? Ethik Med 22:89–102
Winkler EC, Reiter-Theil S, Lange-Riess D, Schmahl-Menges N, Hiddemann W (2009) Patient involvement in decisions to limit treatment: the crucial role of agreement between physician and patient. J Clin Oncol 27:2225–2230
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B. Alt-Epping, F. Nauck und B. Jaspers geben an, dass kein Interessenkonflikt besteht.
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Alt-Epping, B., Nauck, F. & Jaspers, B. Was ist das Problematische an der Palliativen Sedierung? – eine Übersicht. Ethik Med 27, 219–231 (2015). https://doi.org/10.1007/s00481-014-0316-6
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DOI: https://doi.org/10.1007/s00481-014-0316-6