Abstract
The increased prevalence of gastroesophageal reflux disease (GERD) in lung transplantation patients has been established; however, many questions persist regarding the relationship of GERD to aspiration and its potential to induce pulmonary allograft failure. Moreover, the biological implications of aspiration in lung transplantation have yet to be fully elucidated. The goal of this review was to assess the relationship between GERD and aspiration, focusing on the role of these events in the development of allograft injury after lung transplantation.
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Acknowledgment
This work was supported by funding from the 2011 SAGES Research Grant Award (PMF) for the study entitled “A noninvasive test to detect markers of aspiration after lung transplantation.”
Disclosure
Drs. Fisichella, Davis, and Kovacs have no conflicts of interest or financial ties to disclose.
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Fisichella, P.M., Davis, C.S. & Kovacs, E.J. A review of the role of GERD-induced aspiration after lung transplantation. Surg Endosc 26, 1201–1204 (2012). https://doi.org/10.1007/s00464-011-2037-y
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DOI: https://doi.org/10.1007/s00464-011-2037-y