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The impact of atraumatic fibrin sealant vs. staple mesh fixation in TAPP hernia repair on chronic pain and quality of life: results of a randomized controlled study

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Abstract

Background

Mesh reinforcement has become the standard of care in the open and laparoscopic repair of inguinal hernia. Chronic pain after inguinal hernia repair is often due to nerve injury by penetrating mesh fixation devices such as staples (ST), tacks, or sutures. In several studies on hernioplasty, atraumatic mesh fixation with fibrin sealant (FS) proved to be efficient in terms of fixation strength and elasticity. Unfortunately, most of these studies did not provide a standardized follow-up and assessment of the development of chronic pain (CP) and the quality of life (QoL). Therefore, a randomized controlled trial comparing CP and QoL after FS fixation of mesh with ST in transabdominal preperitoneal hernioplasty (TAPP) was performed at our department. The primary end point of our study was to assess the patient outcome by using a visual analog scale (VAS) and the short form 36 (SF-36). The evaluation of recurrence rates was the secondary aim.

Methods

According to the randomization, a macroporous mesh (TiMESH®) was fixed in group A (44 patients with 54 inguinal hernias) with FS (TISSEEL) or in group B (45 patients with 56 inguinal hernias) with ST (EMS® Stapler). The observation period was 1 year with regular clinical check ups and assessment of VAS and SF-36.

Results

Patient characteristics expressed by BMI, ASA scores, and Schumpelick hernia classification were similar in both treatment groups. In each group there was one recurrence within 8 (FS) and 9 months (ST) postsurgery. The mean preoperative pain values scored by VAS were 1.7 (range = 0–7.5) in the FS group and 2.2 (range = 0–6) in the ST group. Postoperative mean VAS scores measured at 1 year postsurgery were 0.4 (range = 0–3) in the FS group and 0.9 (range = 0–7.5) in the ST group. One year postsurgery there was no significant difference between the two groups with respect to the parameter pain in the SF-36 and VAS.

Conclusion

Fibrin sealant fixation leads to a low rate of hernia recurrence and avoids tissue trauma. ST provide similar results in the hand of the expert but bear inherent risks of complications due to tissue perforation.

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Disclosure

Prof. Redl works as senior consultant for Baxter Biosciences. Drs. Fortelny, Petter-Puchner, May, Jaksch, and Benesch, Mr. Kkakpour, and Prof. Glaser have no conflicts of interest or financial ties to disclose.

Author information

Authors and Affiliations

  1. Department of General, Visceral and Oncological Surgery, Wilhelminenspital, Vienna, Austria

    R. H. Fortelny, C. May & K. S. Glaser

  2. Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Donaueschingenstrasse 13, 1200, Vienna, Austria

    A. H. Petter-Puchner, Z. Khakpour & H. Redl

  3. Department of Anesthesiology, Wilhelminenspital, Vienna, Austria

    W. Jaksch

  4. University of Vienna, Vienna, Austria

    T. Benesch

Authors
  1. R. H. Fortelny
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  2. A. H. Petter-Puchner
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  3. C. May
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  4. W. Jaksch
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  5. T. Benesch
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  6. Z. Khakpour
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  7. H. Redl
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  8. K. S. Glaser
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Corresponding author

Correspondence to A. H. Petter-Puchner.

Additional information

R. H. Fortelny and A. H. Petter-Puchner contributed equally to this work.

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Fortelny, R.H., Petter-Puchner, A.H., May, C. et al. The impact of atraumatic fibrin sealant vs. staple mesh fixation in TAPP hernia repair on chronic pain and quality of life: results of a randomized controlled study. Surg Endosc 26, 249–254 (2012). https://doi.org/10.1007/s00464-011-1862-3

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  • DOI: https://doi.org/10.1007/s00464-011-1862-3

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