Zusammenfassung
Die zunehmenden Möglichkeiten der Fundusbildgebung waren eine wichtige Voraussetzung für die Forschungsfortschritte bei Netzhauterkrankungen. Die monochromatische und die Farbphotographie boten Lichtbildaufnahmen des Augenhintergrundes. Die Einführung der Fluoreszein-Angiographie ermöglichte es Ophthalmologen, die vaskuläre Anatomie und Physiologie in zuvor unerreichbarer Weise zu untersuchen und zu dokumentieren [1]. Die Angiographie mit Indozyaningrün erweiterte die Möglichkeiten, den okulären Blutkreislauf abzubilden, insbesondere den der Choroidea [2]. Mit Hilfe dieser Farbstoffe wurde es möglich, indirekt Informationen über andere Schichten des Augenhintergrundes zu erhalten, im Speziellen über das retinale Pigmentepithel (RPE). Diese indirekten Methoden umfassen die Suche nach einer erhöhten oder verminderten Transmission der darunterliegenden choroidalen Fluoreszenz, eine Beurteilung der Menge von Färbung und Leckage sowie die Nutzung stereoskoper Hinweise zur Konturbestimmung auf der Ebene des RPE.
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Spaide, R. (2011). Imaging bei AMD. In: Altersabhängige Makuladegeneration. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-20870-6_9
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