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Lipoproteins in Patients with Isolated Hyperuricemia

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Purine and Pyrimidine Metabolism in Man IX

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 431))

Summary

There have been described abnormalities in the lipoprotein profile of hyperuricemic patients, it has not been clarified wether these abnormalities are due to the hyperuricemia or to the dyslipema often associated to these patients. Our aim is to study the apolipoprotein profile in hyperuricemic patients without dyslipemia compared to a control population.

This work was supported by grant from Junta de Andalucia (96/212).

Correspondence to: F.J. Tinahones, c/ Ayala n 28 4 6 A, Málaga 29002, Spain

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References

  1. Berkowitz D. Gout hyperlipidemia and diabetes interrelationship. JAMA 1966; 197: 117–120.

    Article  Google Scholar 

  2. Wiedmann E, Rose HG, Schwartz E. Plasma lipoproteins, glucose tolerance and insulin response in primary gout. Am J Med 1972;53: 299–307.

    Article  Google Scholar 

  3. Becker JH. Gout and serum cholesterol. Wis Med J 1960; 59: 735.

    PubMed  CAS  Google Scholar 

  4. Mielants H, Veges EM, Weerdy AD. Gout and its relation to lipid metabolism.1 serum uric acid, lipid and lipoprotein levels in gout. Ann Rheum Dis 1973; 32: 501–505.

    Article  PubMed  CAS  Google Scholar 

  5. Emmerson BT, Knowles BR. Triglyceride concentrations in primary gout and gout of chronic lead nephropathy. Metabolism 1971; 20: 721–729.

    Article  PubMed  CAS  Google Scholar 

  6. Collantes E, Añón J, Tinahones FJ, Sánchez P. Perfil lipídico asociado a hiperuricemia asintomática. Estudio protocolizado de 77 individuos en nuestro medio. Rev Esp Reumatol 1989; 16: 129–131.

    Google Scholar 

  7. Faller J, Fox IH. Ethanol induced hyperuricemia:evidence for increased urate production by activation of adenine nucleotide turnover. N Engl J Med 1982; 307: 1598–1603.

    Article  PubMed  CAS  Google Scholar 

  8. Gibson T, Grahame R. Gout and hyperlipidaemia. Ann Rheum Dis 1974; 33: 298–303.

    Article  PubMed  CAS  Google Scholar 

  9. Collantes E, Pineda M, Anon J, Sanchez-Guijo P. Hyperuricemia-hyperlipemia association in the abscence of obesity and alcohol abuse. Clin Rheumatol 1990; 9: 28–31.

    Article  Google Scholar 

  10. Ulreich A, Korner GM, Pfeiffer KP. Serum lipids and lipoproteins in patients with primary gout. Rheumatol Int 1985; 5: 73–77.

    Article  PubMed  CAS  Google Scholar 

  11. Jacobelli S, Arteaga A, Bidegain F. Cholesterol distribution among lipoprotein fractions in patients with gout and normal controls. J Rheumatol 1986; 13: 774–777.

    PubMed  CAS  Google Scholar 

  12. Matsubara K, Matsuzawa Y, Jiao S, Takama T, Masaharu K, Tami S. Relationship between hypertriglyceridemia and uric acid production in primary gout. Metabolism 1989; 38: 689–701.

    Article  Google Scholar 

  13. Darlington L, Slak J, Scott JT. Family study of lipid and purine levels in gout patients. Ann Rheum Dis 1982; 41: 253–256.

    Article  PubMed  CAS  Google Scholar 

  14. MacFarlane DG, Midwinter CA, Dieppe PA, Bolton CH, Hartg M. Demostration of an abnormality of C apoprotein of very low density lipoprotein in patients wiyh gout. Ann Rheum Dis 1985; 44: 390–394.

    Article  PubMed  CAS  Google Scholar 

  15. Tinahones FJ, Collantes E, Gonzalez A, C-Soriguer F, Añön J, Sánchez P. Increased VLDL levels and disminished renal excretion of uric acid in hyperuricemic-hypertrigliceridemic patients. Br J Rheumatol 1995; 34: 920–924.

    Article  PubMed  CAS  Google Scholar 

  16. Scanu AM, Edelstein C. Solubility in aqueous solution or ethanol of the small molecular weight peptides of serum very low density and high density lipoproteins relevant to the recovery problem during delipidation of serum lipoprotein. Anal Biochem 1971; 44: 576–588.

    Article  PubMed  CAS  Google Scholar 

  17. Deckel RJ. Plasma triglyceride determine structure composition in low and high density lipoproteins. Arteriosclerosis 1984; 4: 225–231.

    Article  Google Scholar 

  18. Takahashi S, Yamamoto T, Moriwaki Y, Tsutsumi Z, Higashino K. Impaired lipoprotein metabolism in patients with primary gout-influence of alcohol intake and body weight. Br J Reumatol 1994; 33: 731–734.

    Article  CAS  Google Scholar 

  19. Bouvenot G, Bartolin R, Sciara M, Delboy C, Arnaud C. Serum uric acid and serum lipids. Statistical correlations report of 1000 cases. Sem Hop Paris 1980; 56: 263–264.

    PubMed  CAS  Google Scholar 

  20. Kullich W, Ulreich A, Klein G. Hyperlipoproteinemia in primary gout and asymptomatic hyperuricemia. Wien Med Wochenschr 1988; 138: 221–225.

    PubMed  CAS  Google Scholar 

  21. Collantes E, Tinahones FJ, Cisnal A, Añön J, Sánchez-Guijo P. Variability of lipid phenotypes in hyperuricemic-hyperlipidemic patients. Clin Rheum 1994; 13: 244–247.

    CAS  Google Scholar 

  22. Collantes E, Tinahones FJ, Pineda M, Soriguer F, Sánchez P. Apoprotein C in hyperuricemic patients. Br J Rheum 1992;31(Suppl): 21.

    Google Scholar 

  23. Thompson G. Apoproteins:determinants of lipoproteins metabolism and indices of coronary rick. Br Heart J 1984; 51: 585–588.

    Article  PubMed  CAS  Google Scholar 

  24. Sveger T, Fex G. Apolipoproteins AI and B levels in adolescente, a trial to define subjects at risk for coronary heart disease. Acta Pediatr Scand 1983; 72: 499–504.

    Article  CAS  Google Scholar 

  25. Avogaro P. Lipid and lipoproteins of lipoproteins in humans atherosclerosis. En:Halpen MJ, editores. Lipid metabolism and its pathology. New York: leum Press, 1985: 17–23.

    Chapter  Google Scholar 

  26. Willian N, Kelley MD. Gout and Disorders of Purine Metabolism. En:Willian N, Kelley MD, Edward DH, Sham R, Clement BS, editores.Textbook of Rheumatology. Filadelfia: anders, 1989.

    Google Scholar 

  27. Moller DE, Flier JS. Mechanisms of disease:insulin resistance-mechanisms, syndromes and implications. N Engl J Med 1991; 325: 938–948.

    Article  PubMed  CAS  Google Scholar 

  28. Zavaroti I, Mazza S, Fantuzzi M, Dall Aglio E, Bonora E, Delsignore R, Passeri M, Reaven GM. Changes in insulin and lipid metabolism in males with asymptomatic hyperuricaemia. J Int Med 1993; 234: 25–30.

    Article  Google Scholar 

  29. Vuorinen-Markkola H, Yki-Järvinen H. Hyperuricemia and insulin resistance. J Clin Endocrinol Metab 1994; 78: 25–29.

    Article  PubMed  CAS  Google Scholar 

  30. Fessel J. High uric acid as an indicator of cardiovascualr disease independence from obesity. Am J Med 1980; 68: 401–404.

    Article  PubMed  CAS  Google Scholar 

  31. Brand. Hyperuricemia as a risk factor of coronary heart disease:The Framinghans study. Ann J Epidemiol 1985; 121: 11–18.

    CAS  Google Scholar 

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Author information

Authors and Affiliations

  1. Section of Endocrinology, Regional hospital of Málaga, Málaga, Spain

    F. J. Tinahones, F. Vazquez & F. J. Soriguer

  2. Section of Rheumatology, Reina Sofia Regional hospital, Córdoba, Spain

    E. Collantes

Authors
  1. F. J. Tinahones
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  2. F. Vazquez
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  3. F. J. Soriguer
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  4. E. Collantes
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Editor information

Editors and Affiliations

  1. Emperor Franz Joseph Hospital, Vienna, Austria

    Andrea Griesmacher  & Mathias M. Müller  & 

  2. University of Vienna, Vienna, Austria

    Peter Chiba

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© 1998 Springer Science+Business Media New York

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Tinahones, F.J., Vazquez, F., Soriguer, F.J., Collantes, E. (1998). Lipoproteins in Patients with Isolated Hyperuricemia. In: Griesmacher, A., Müller, M.M., Chiba, P. (eds) Purine and Pyrimidine Metabolism in Man IX. Advances in Experimental Medicine and Biology, vol 431. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-5381-6_12

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  • DOI: https://doi.org/10.1007/978-1-4615-5381-6_12

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-7456-5

  • Online ISBN: 978-1-4615-5381-6

  • eBook Packages: Springer Book Archive

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