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Collagen Diversity, Synthesis and Assembly

  • Chapter
Collagen

Abstract

The vertebrate collagen superfamily now includes over 50 collagens and collagen-like proteins. Here, their different structures are described, as well as their diverse forms of supramolecular assembly. Also presented here are the various steps in collagen biosynthesis, both intracellular and extracellular, and the functions of the collagen-specific post-translational modifications. Assembly of collagen fibrils, both in vitro and in vivo, is reviewed, including the mechanisms that control this process and the interactions involved. Finally, recent developments in the supramolecular assembly of collagen-like peptides are discussed.

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  1. D.J.S. Hulmes
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  1. Department of Biomaterials, Max Planck Institute of Colloids and Interfaces, 14424 Potsdam, Germany

    Peter Fratzl

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Hulmes, D. (2008). Collagen Diversity, Synthesis and Assembly. In: Fratzl, P. (eds) Collagen. Springer, Boston, MA. https://doi.org/10.1007/978-0-387-73906-9_2

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  • DOI: https://doi.org/10.1007/978-0-387-73906-9_2

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-387-73905-2

  • Online ISBN: 978-0-387-73906-9

  • eBook Packages: EngineeringEngineering (R0)

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