Tipp

Zervixkarzinom

Systemische Therapie in einem kurativen multimodalen Konzept

Zeitschrift:: Wiener klinisches Magazin > Ausgabe 1/2013

Autor:: Prof. Dr. B. Wörmann

» Jetzt Zugang zum Volltext erhalten

Wichtige Hinweise

Der Originalbeitrag wurde publiziert in: Der Onkologe (2012;18:56–60). Nachdruck mit freundlicher Genehmigung des Autors.

Ohne Zusammenfassung

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Jetzt einloggen Kostenlos registrieren

Deutsche Krebsgesellschaft e. V. (DKG) und Deutsche Gesellschaft für Gynäkologie und Geburtshilfe (DGGG) (2008) Interdisziplinäre S2k.Leitlinie: Diagnostik und Therapie des Zervixkarzinoms. AWMF Leitlinienregister, Nr. 032/033. http//http://www.awmf.org/leitlinien/aktuelle-leitlinien.html

Blohmer JU, Paepke S, Sehouli J et al (2011) Randomized phase III trial of sequential adjuvant chemoradiotherapy with or without erythropoietin alpha in patients with high-risk cervical cancer: results of the NOGGO-AGO intergroup study. J Clin Oncol 28:3791–3799 CrossRef

Chemoradiotherapy for Cervical Cancer Meta-Analysis Collaboration (2008) Reducing uncertainties about the effects of chemoradiotherapy for cervical cancer: a systematic review and meta-analysis of individual patient data from 18 randomized trials. J Clin Oncol 26:5802–5812 CrossRef

Duenas-Gonzalez A, Zarbá JJ, Patel F et al (2011) Phase III, open-label, randomized study comparing concurrent gemcitabine plus cisplatin and radiation followed by adjuvant gemcitabine and cisplatin versus concurrent cisplatin and radiation in patients with stage IIB to IVA carcinoma of the cervix. J Clin Oncol 29:1678–1685 PubMedCrossRef

Einstein MH, Novetsky AP, Garg M et al (2007) Survival and toxicity differences between 5-day and weekly cisplatin in patients with locally advanced cervical cancer. Cancer 109:48–53 PubMedCrossRef

Green J, Kirwan J, Tierney J et al (2005) Concomitant chemotherapy and radiation therapy for cancer of the uterine cervix. Cochrane Database Syst Rev:CD002225

Haie-Meder C, Morice P, Castiglione M et al (2010) Cervical cancer: ESMO clinical practice guidelines on diagnosis, treatment and follow-up. Ann Oncol 21(Suppl 5):37–v40 CrossRef

Keys HM, Bundy BN, Stehman FB et al (1999) Cisplatin, radiation and adjuvant hysterectomy compared with radiation and adjuvant hysterectomy for bulky stage IB cervical carcinoma. N Engl J Med 340:1154–1161 PubMedCrossRef

Kleinerman R, Kosary C, Hildesheim A (2006) New malignancies following cancer of the cervix uteri, vagina and vulva. In: Curtis RE et al (Hrsg) New malignancies among cancer survivors. SEER Cancer Registries, 1973–2000. http://seer.cancer.gov

10.

Lukka H, Hirte H, Fyles A et al (2002) Concurrent cisplatin-based chemotherapy plus radiotherapy for cervical cancer-a meta-analysis. Clin Oncol 14:203–212 CrossRef

11.

McCaffrey R, Bahtiyar M, Kohorn EI (2011) Neoadjuvant and adjuvant chemotherapy of cervical cancer. Int J Gynecol Oncol 21:535–544 CrossRef

12.

Morris M, Eifel PJ, Lu J et al (1999) Pelvic radiation with concurrent chemotherapy compared with plevic and paraaortic radiation for high-risk cervical cancer. N Engl J Med 340:1137–1143 PubMedCrossRef

13.

National Cancer Institute (1999) Clinical announcement on cervical cancer. National Institutes of Health, Bethesda, MD. http://rex.nci.nih.gov/massmedia/pressreleases/cervicalcancer.html

14.

NCCN Clinical Practice Guidelines in Oncology: Cervical Cancer, Version 1.2012

15.

Neoadjuvant Chemotherapy for Cervical Cancer Meta-analysis Collaboration (2003) Neoadjuvant chemotherapy for locally advanced cervical cancer: a systematic review and meta-analysis of individual patient data from 21 randomised trials. Eur J Cancer 39:2470–2486 CrossRef

16.

Peters WA, Liu PY, Barrett RGW et al (2000) Cisplatin, 5-Fluorouracil plus radiation therapy are superior to radiation therapy as adjunctive therapy in high risk, early stage carcinoma of the cervix after radical hysterectomy and pelvic lymphadenectomy: report of a phase III inter group study. J Clin Oncol 18:1606–1613 PubMed

17.

Rose PG, Bundy BN, Watkins EB et al (1999) Concurrent cisplatin-based radiotherapy and chemotherapy for locally advanced cervical cancer. N Engl J Med 340:1144–1153 PubMedCrossRef

18.

Ryu SY, Lee WM, Kim K et al (2011) Randomized clinical trial of weekly vs triweekly cisplatin-based chemotherapy concurrent with radiochemotherapy in the treatment of locally advanced cervical cancer. Int J Radiat Oncol Biol Phys 81:577–581 CrossRef

19.

Thomas GM (1999) Improved treatment for cervical cancer – concurrent chemotherapy and radiotherapy. N Engl J Med 340:1198–1200 PubMedCrossRef

20.

Thomas GM (2011) Are we making progress in curing advanced cervical cancer? J Clin Oncol 29:1654–1655 PubMedCrossRef

21.

Tierney J, Neoadjuvant Chemotherapy for Cervical Cancer Meta-analysis (NACCCMA) Collaboration (2009) Neoadjuvant chemotherapy for locally advanced cervix cancer. Cochrane Database Syst Rev:CD001774

22.

Wang N, Guan QL, Wang K et al (2011) Radiochemotherapy versus radiotherapy in locally advanced cervical cancer: a meta-analysis. Arch Gynecol Obstet 283:103–108 PubMedCrossRef

23.

Whitney CW, Sause W, Bundy BN et al (1999) Randomised comparison of fluorouracil plus cisplatin versus hydroxyurea in stage IIB/IVA in carcinoma of the cervix. J Clin Oncol 17:1339–1348 PubMed

Titel: Zervixkarzinom
Systemische Therapie in einem kurativen multimodalen Konzept
Autor:: Prof. Dr. B. Wörmann
Publikationsdatum: 01.02.2013
DOI: https://doi.org/10.1007/s00740-013-0075-x
Verlag: Springer Vienna
Zeitschrift: Wiener klinisches Magazin
Ausgabe 1/2013
Print ISSN: 1869-1757
Elektronische ISSN: 1613-7817

Springer Medizin Österreich

Tipp

Weitere Artikel dieser Ausgabe durch Wischen aufrufen

Ohne Zusammenfassung

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten