Skip to main content
main-content

Tipp

Weitere Artikel dieser Ausgabe durch Wischen aufrufen

01.07.2014 | main topic | Ausgabe 13-14/2014

Wiener Medizinische Wochenschrift 13-14/2014

Vitiligo: what’s new in the psycho-neuro-endocrine-immune connection and related treatments

Zeitschrift:
Wiener Medizinische Wochenschrift > Ausgabe 13-14/2014
Autoren:
MD Torello Lotti, Matteo Zanardelli, MD Angelo Massimiliano D’Erme

Summary

Vitiligo is an acquired depigmentary skin disorder of unknown origin characterized by well-demarcated, white macules of varying size and distribution. Despite relevant new research and progresses, why melanocytes disappear to induce the characteristic achromic lesions of vitiligo is not fully understood. In spite of recent findings implicating genetic, immune and oxidative stress factors, the exact pathogenesis of vitiligo remains obscure. An innovative concept based on a functional cross-talk between the nervous and immune system is emerging. Neuropeptides released from peripheral nerve endings could synergize with new cytokines to adversely affect melanocyte function and viability. Evidence is increasing regarding the role of neuropeptides in the pathogenesis of vitiligo and a new winning approach to vitiligo therapy based on neuropeptides regulation is at the horizon.

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Literatur
Über diesen Artikel

Weitere Artikel der Ausgabe 13-14/2014

Wiener Medizinische Wochenschrift 13-14/2014 Zur Ausgabe