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Erschienen in: Wiener klinische Wochenschrift 17-18/2012

01.09.2012 | original article

Visual evoked potentials in patients with pineal gland cyst

verfasst von: Jelena Bosnjak, MD, PhD, Ivan Mikula, MD, PhD, Snjezana Miskov, MD, PhD, Mislav Budisic, MD, Goran Ivkic, MD, PhD, Vida Demarin, MD, PhD

Erschienen in: Wiener klinische Wochenschrift | Ausgabe 17-18/2012

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Summary

Aims

The functional effect of the pineal gland cyst is difficult to evaluate with visual field examination. The aim of this study is to investigate the usefulness of visual evoked potentials (VEP) in patients with pineal gland cyst due to the possible compression on the visual pathway.

Subjects and methods

Black-and-white pattern-reversal checkerboard VEP were recorded in 75 patients (50 females and 25 males, mean age 26.3 ± 15.7 and 25.6 ± 17.6 years, respectively) with pineal gland cyst detected on magnetic resonance of the brain (subject group) and 75 age and sex-matched control subjects (control group). Amplitudes and P100 latencies were collected and later grouped as: (1) normal finding; (2) prechiasmal; (3) prechiasmal and postchiasmal; and (4) postchiasmal dysfunction.

Results

P100 latencies differed significantly between subject (110.26 ± 13.23 ms) and control group (101.01 ± 5.36 ms) (p < 0.01). Findings of the VEP differed significantly (p < 0.01) between subject and control group, mainly due to the postchiasmal dysfunction frequency in subject group. Findings of the VEP differed significantly according to the pineal gland cyst volume (p = 0.006) with more frequent postchiasmal dysfunctions among subjects with larger cysts. Postchiasmal changes were significantly more frequent in patients with described compression of the cyst on surrounding brain structures (p = 0.016).

Conclusions

Postchiasmal dysfunction on VEP can be seen in patients with pineal gland cyst, mostly with larger cysts and with compression of the cyst on surrounding brain structures. VEP serve as a useful method to determine functional impairment of the visual pathway in patients with pineal gland cyst.
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Metadaten
Titel
Visual evoked potentials in patients with pineal gland cyst
verfasst von
Jelena Bosnjak, MD, PhD
Ivan Mikula, MD, PhD
Snjezana Miskov, MD, PhD
Mislav Budisic, MD
Goran Ivkic, MD, PhD
Vida Demarin, MD, PhD
Publikationsdatum
01.09.2012
Verlag
Springer Vienna
Erschienen in
Wiener klinische Wochenschrift / Ausgabe 17-18/2012
Print ISSN: 0043-5325
Elektronische ISSN: 1613-7671
DOI
https://doi.org/10.1007/s00508-012-0215-0

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