Skip to main content

Tipp

Weitere Artikel dieser Ausgabe durch Wischen aufrufen

Erschienen in: Urologie in der Praxis 3/2021

25.05.2021 | Urologie | Originalien

Behandlung rezidivierender Harnwegsinfekte bei PatientInnen mit neurogener Blasenfunktionsstörung

verfasst von: Julia Neuenschwander, Prof. Dr. med. Jürgen Pannek

Erschienen in: Urologie in der Praxis | Ausgabe 3/2021

Einloggen, um Zugang zu erhalten

Zusammenfassung

Harnwegsinfekte (HWI) gehören zu den häufigsten Komplikationen bei PatientInnen mit neurogener Funktionsstörung des unteren Harntrakts. Sie sind mit einer erhöhten Morbidität, Mortalität und einer verschlechterten Lebensqualität assoziiert. Zu den Risikofaktoren gehören eine suboptimal eingestellte Blasenfunktion und die Verwendung von Kathetern. Nur symptomatische Infekte sollten behandelt werden, die Therapie einer asymptomatischen Bakteriurie ist nicht indiziert, und somit ist ein Screening nicht sinnvoll. Die Symptome eines HWI können unspezifisch und anders als bei Personen ohne neurologische Grunderkrankung sein. Vor Therapiebeginn sollte eine Urinkultur angelegt werden, und es sollte, wenn immer möglich, resistenzgerecht therapiert werden. Rezidivierende HWI sind häufig; eine antibiotische Prophylaxe sollte wegen der geringen Effektivität und der Begünstigung multiresistenter Keime möglichst vermieden werden. Es existieren verschiedene nichtantibiotische Alternativen; da jedoch für kein Verfahren ein evidenzbasierter Wirknachweis besteht, ist ein individuelles Vorgehen mit Modifikation der Prophylaxe nach klinischem Verlauf erforderlich.
Literatur
1.
Zurück zum Zitat Esclarin De Ruz A, Garcia Leoni E, Herruzo Cabrera R (2000) Epidemiology and risk factors for urinary tract infection in patients with spinal cord injury. J Urol 164:1285–1289 PubMedCrossRef Esclarin De Ruz A, Garcia Leoni E, Herruzo Cabrera R (2000) Epidemiology and risk factors for urinary tract infection in patients with spinal cord injury. J Urol 164:1285–1289 PubMedCrossRef
2.
Zurück zum Zitat Biering-Sorensen F, Nielans HM, Dorflinger T, Sorensen B (1999) Urological situation five years after spinal cord injury. Scand J Urol Nephrol 33:157–161 PubMedCrossRef Biering-Sorensen F, Nielans HM, Dorflinger T, Sorensen B (1999) Urological situation five years after spinal cord injury. Scand J Urol Nephrol 33:157–161 PubMedCrossRef
3.
Zurück zum Zitat Biering-Sorensen F, Bagi P, Hoiby N (2001) Urinary tract infections in patients with spinal cord lesions: treatment and prevention. Drugs 61:1275–1287 PubMedCrossRef Biering-Sorensen F, Bagi P, Hoiby N (2001) Urinary tract infections in patients with spinal cord lesions: treatment and prevention. Drugs 61:1275–1287 PubMedCrossRef
4.
Zurück zum Zitat Hinkel A, Finke W, Botel U, Gatermann SG, Pannek J (2004) Increasing resistance against antibiotics in bacteria isolated from the lower urinary tract of an outpatient population of spinal cord injury patients. Urol Int 73:143–148 PubMedCrossRef Hinkel A, Finke W, Botel U, Gatermann SG, Pannek J (2004) Increasing resistance against antibiotics in bacteria isolated from the lower urinary tract of an outpatient population of spinal cord injury patients. Urol Int 73:143–148 PubMedCrossRef
5.
Zurück zum Zitat Goble NM, Clarke T, Hammonds JC (1989) Histological changes in the urinary bladder secondary to urethral catheterisation. Br J Urol 63:354–357 PubMedCrossRef Goble NM, Clarke T, Hammonds JC (1989) Histological changes in the urinary bladder secondary to urethral catheterisation. Br J Urol 63:354–357 PubMedCrossRef
6.
Zurück zum Zitat Glahn BE, Braendstrup O, Olesen HP (1988) Influence of drainage conditions on mucosal bladder damage by indwelling catheters. II. Histological study. Scand J Urol Nephrol 22:93–99 PubMedCrossRef Glahn BE, Braendstrup O, Olesen HP (1988) Influence of drainage conditions on mucosal bladder damage by indwelling catheters. II. Histological study. Scand J Urol Nephrol 22:93–99 PubMedCrossRef
7.
Zurück zum Zitat Delnay KM, Stonehill WH, Goldman H, Jukkola AF, Dmochowski RR (1999) Bladder histological changes associated with chronic indwelling urinary catheter. J Urol 161:1106–1108 (discussion 8–9) PubMedCrossRef Delnay KM, Stonehill WH, Goldman H, Jukkola AF, Dmochowski RR (1999) Bladder histological changes associated with chronic indwelling urinary catheter. J Urol 161:1106–1108 (discussion 8–9) PubMedCrossRef
8.
Zurück zum Zitat Warren JW (2001) Catheter-associated urinary tract infections. Int J Antimicrob Agents 17:299–303 PubMedCrossRef Warren JW (2001) Catheter-associated urinary tract infections. Int J Antimicrob Agents 17:299–303 PubMedCrossRef
9.
Zurück zum Zitat Brommer B, Engel O, Kopp MA et al (2016) Spinal cord injury-induced immune deficiency syndrome enhances infection susceptibility dependent on lesion level. Brain 139:692–707 PubMedPubMedCentralCrossRef Brommer B, Engel O, Kopp MA et al (2016) Spinal cord injury-induced immune deficiency syndrome enhances infection susceptibility dependent on lesion level. Brain 139:692–707 PubMedPubMedCentralCrossRef
10.
Zurück zum Zitat Lucin KM, Sanders VM, Jones TB, Malarkey WB, Popovich PG (2007) Impaired antibody synthesis after spinal cord injury is level dependent and is due to sympathetic nervous system dysregulation. Exp Neurol 207:75–84 PubMedPubMedCentralCrossRef Lucin KM, Sanders VM, Jones TB, Malarkey WB, Popovich PG (2007) Impaired antibody synthesis after spinal cord injury is level dependent and is due to sympathetic nervous system dysregulation. Exp Neurol 207:75–84 PubMedPubMedCentralCrossRef
11.
Zurück zum Zitat Hong J, Chang A, Liu Y, Wang J, Fehlings MG (2019) Incomplete spinal cord injury reverses the level-dependence of spinal cord injury immune deficiency syndrome. Int J Mol Sci 1:20 Hong J, Chang A, Liu Y, Wang J, Fehlings MG (2019) Incomplete spinal cord injury reverses the level-dependence of spinal cord injury immune deficiency syndrome. Int J Mol Sci 1:20
12.
Zurück zum Zitat EAU (2020) EAU Guidelines. EAU Annual Congress, Amsterdam.. ISBN 978-94-92671-07‑3 EAU (2020) EAU Guidelines. EAU Annual Congress, Amsterdam.. ISBN 978-94-92671-07‑3
13.
Zurück zum Zitat Goetz LL, Cardenas DD, Kennelly M et al (2013) International spinal cord injury urinary tract infection basic data set. Spinal Cord 51:700–704 PubMedCrossRef Goetz LL, Cardenas DD, Kennelly M et al (2013) International spinal cord injury urinary tract infection basic data set. Spinal Cord 51:700–704 PubMedCrossRef
14.
Zurück zum Zitat Hoffman JM, Wadhwani R, Kelly E, Dixit B, Cardenas DD (2004) Nitrite and leukocyte dipstick testing for urinary tract infection in individuals with spinal cord injury. J Spinal Cord Med 27:128–132 PubMedCrossRef Hoffman JM, Wadhwani R, Kelly E, Dixit B, Cardenas DD (2004) Nitrite and leukocyte dipstick testing for urinary tract infection in individuals with spinal cord injury. J Spinal Cord Med 27:128–132 PubMedCrossRef
15.
Zurück zum Zitat Mukai S, Shigemura K, Nomi M et al (2016) Retrospective study for risk factors for febrile UTI in spinal cord injury patients with routine concomitant intermittent catheterization in outpatient settings. Spinal Cord 54:69–72 PubMedCrossRef Mukai S, Shigemura K, Nomi M et al (2016) Retrospective study for risk factors for febrile UTI in spinal cord injury patients with routine concomitant intermittent catheterization in outpatient settings. Spinal Cord 54:69–72 PubMedCrossRef
16.
Zurück zum Zitat Anderson CE, Chamberlain JD, Jordan X et al (2019) Bladder emptying method is the primary determinant of urinary tract infections in patients with spinal cord injury: results from a prospective rehabilitation cohort study. BJU Int 123:342–352 PubMedCrossRef Anderson CE, Chamberlain JD, Jordan X et al (2019) Bladder emptying method is the primary determinant of urinary tract infections in patients with spinal cord injury: results from a prospective rehabilitation cohort study. BJU Int 123:342–352 PubMedCrossRef
17.
Zurück zum Zitat Krebs J, Wollner J, Pannek J (2016) Risk factors for symptomatic urinary tract infections in individuals with chronic neurogenic lower urinary tract dysfunction. Spinal Cord 54:682–686 PubMedCrossRef Krebs J, Wollner J, Pannek J (2016) Risk factors for symptomatic urinary tract infections in individuals with chronic neurogenic lower urinary tract dysfunction. Spinal Cord 54:682–686 PubMedCrossRef
19.
Zurück zum Zitat Farrelly E, Lindbo L, Wijkstrom H, Seiger A (2020) The Stockholm Spinal Cord Uro Study: 2. Urinary tract infections in a regional prevalence group: frequency, symptoms and treatment strategies. Scand J Urol 54:155–161 PubMedCrossRef Farrelly E, Lindbo L, Wijkstrom H, Seiger A (2020) The Stockholm Spinal Cord Uro Study: 2. Urinary tract infections in a regional prevalence group: frequency, symptoms and treatment strategies. Scand J Urol 54:155–161 PubMedCrossRef
20.
Zurück zum Zitat Shigemura K, Kitagawa K, Nomi M, Yanagiuchi A, Sengoku A, Fujisawa M (2020) Risk factors for febrile genito-urinary infection in the catheterized patients by with spinal cord injury-associated chronic neurogenic lower urinary tract dysfunction evaluated by urodynamic study and cystography: a retrospective study. World J Urol 38:733–740 PubMedCrossRef Shigemura K, Kitagawa K, Nomi M, Yanagiuchi A, Sengoku A, Fujisawa M (2020) Risk factors for febrile genito-urinary infection in the catheterized patients by with spinal cord injury-associated chronic neurogenic lower urinary tract dysfunction evaluated by urodynamic study and cystography: a retrospective study. World J Urol 38:733–740 PubMedCrossRef
21.
Zurück zum Zitat Everaert K, Lumen N, Kerckhaert W, Willaert P, van Driel M (2009) Urinary tract infections in spinal cord injury: prevention and treatment guidelines. Acta Clin Belg 64:335–340 PubMedCrossRef Everaert K, Lumen N, Kerckhaert W, Willaert P, van Driel M (2009) Urinary tract infections in spinal cord injury: prevention and treatment guidelines. Acta Clin Belg 64:335–340 PubMedCrossRef
22.
Zurück zum Zitat Hooton TM, Bradley SF, Cardenas DD et al (2010) Diagnosis, prevention, and treatment of catheter-associated urinary tract infection in adults: 2009 International Clinical Practice Guidelines from the Infectious Diseases Society of America. Clin Infect Dis 1(50):625–663 CrossRef Hooton TM, Bradley SF, Cardenas DD et al (2010) Diagnosis, prevention, and treatment of catheter-associated urinary tract infection in adults: 2009 International Clinical Practice Guidelines from the Infectious Diseases Society of America. Clin Infect Dis 1(50):625–663 CrossRef
23.
Zurück zum Zitat Clark R, Welk B (2018) The ability of prior urinary cultures results to predict future culture results in neurogenic bladder patients. Neurourol Urodyn 37:2645–2650 PubMedCrossRef Clark R, Welk B (2018) The ability of prior urinary cultures results to predict future culture results in neurogenic bladder patients. Neurourol Urodyn 37:2645–2650 PubMedCrossRef
24.
Zurück zum Zitat Pannek J, Pannek-Rademacher S, Wollner J (2018) Treatment of complicated urinary tract infections in individuals with chronic Neurogenic lower urinary tract dysfunction: are antibiotics mandatory? Urol Int 100:434–439 PubMedCrossRef Pannek J, Pannek-Rademacher S, Wollner J (2018) Treatment of complicated urinary tract infections in individuals with chronic Neurogenic lower urinary tract dysfunction: are antibiotics mandatory? Urol Int 100:434–439 PubMedCrossRef
25.
Zurück zum Zitat Del Popolo G, Nelli F (2018) Recurrent bacterial symptomatic cystitis: A pilot study on a new natural option for treatment. Archivio italiano di urologia, andrologia 30(90):101–103 CrossRef Del Popolo G, Nelli F (2018) Recurrent bacterial symptomatic cystitis: A pilot study on a new natural option for treatment. Archivio italiano di urologia, andrologia 30(90):101–103 CrossRef
26.
Zurück zum Zitat Pannek J, Pannek-Rademacher S, Cachin-Jus M (2014) Organ-preserving treatment of an epididymal abscess in a patient with spinal cord injury. Spinal Cord 52(Suppl 1):7–8 CrossRef Pannek J, Pannek-Rademacher S, Cachin-Jus M (2014) Organ-preserving treatment of an epididymal abscess in a patient with spinal cord injury. Spinal Cord 52(Suppl 1):7–8 CrossRef
27.
Zurück zum Zitat Kumazawa J, Matsumoto T (1992) The dipstick test in the diagnosis of UTI and the effect of pretreatment catheter exchange in catheter-associated UTI. Infection 20(Suppl 3):S157–9 PubMedCrossRef Kumazawa J, Matsumoto T (1992) The dipstick test in the diagnosis of UTI and the effect of pretreatment catheter exchange in catheter-associated UTI. Infection 20(Suppl 3):S157–9 PubMedCrossRef
28.
Zurück zum Zitat DeFoor W, Reddy P, Reed M et al (2017) Results of a prospective randomized control trial comparing hydrophilic to uncoated catheters in children with neurogenic bladder. J Pediatr Urol 13(373):e1–e5 DeFoor W, Reddy P, Reed M et al (2017) Results of a prospective randomized control trial comparing hydrophilic to uncoated catheters in children with neurogenic bladder. J Pediatr Urol 13(373):e1–e5
29.
Zurück zum Zitat Lucas EJ, Baxter C, Singh C et al (2016) Comparison of the microbiological milieu of patients randomized to either hydrophilic or conventional PVC catheters for clean intermittent catheterization. J Pediatr Urol 12(172):e1–8 Lucas EJ, Baxter C, Singh C et al (2016) Comparison of the microbiological milieu of patients randomized to either hydrophilic or conventional PVC catheters for clean intermittent catheterization. J Pediatr Urol 12(172):e1–8
30.
Zurück zum Zitat Christensen P, Bazzocchi G, Coggrave M et al (2006) A randomized, controlled trial of transanal irrigation versus conservative bowel management in spinal cord-injured patients. Gastroenterology 131:738–747 PubMedCrossRef Christensen P, Bazzocchi G, Coggrave M et al (2006) A randomized, controlled trial of transanal irrigation versus conservative bowel management in spinal cord-injured patients. Gastroenterology 131:738–747 PubMedCrossRef
31.
Zurück zum Zitat Emmanuel A, Kumar G, Christensen P et al (2016) Long-term cost-effectiveness of transanal irrigation in patients with neurogenic bowel dysfunction. PLoS ONE 11:e159394 PubMedPubMedCentralCrossRef Emmanuel A, Kumar G, Christensen P et al (2016) Long-term cost-effectiveness of transanal irrigation in patients with neurogenic bowel dysfunction. PLoS ONE 11:e159394 PubMedPubMedCentralCrossRef
32.
Zurück zum Zitat Lee BB, Haran MJ, Hunt LM et al (2007) Spinal-injured neuropathic bladder antisepsis (SINBA) trial. Spinal Cord 45:542–550 PubMedCrossRef Lee BB, Haran MJ, Hunt LM et al (2007) Spinal-injured neuropathic bladder antisepsis (SINBA) trial. Spinal Cord 45:542–550 PubMedCrossRef
33.
Zurück zum Zitat Günther M, Noll F, Nützel R, Gläser E, Kramer G, Stöhrer M (2002) Harnwegsinfektprophylaxe. Urologe B 42(3):218–220 CrossRef Günther M, Noll F, Nützel R, Gläser E, Kramer G, Stöhrer M (2002) Harnwegsinfektprophylaxe. Urologe B 42(3):218–220 CrossRef
34.
Zurück zum Zitat Ditscheid B, Funfstuck R, Busch M, Schubert R, Gerth J, Jahreis G (2005) Effect of L‑methionine supplementation on plasma homocysteine and other free amino acids: a placebo-controlled double-blind cross-over study. Eur J Clin Nutr 59:768–775 PubMedCrossRef Ditscheid B, Funfstuck R, Busch M, Schubert R, Gerth J, Jahreis G (2005) Effect of L‑methionine supplementation on plasma homocysteine and other free amino acids: a placebo-controlled double-blind cross-over study. Eur J Clin Nutr 59:768–775 PubMedCrossRef
35.
Zurück zum Zitat Stanger O, Herrmann W, Pietrzik K et al (2003) DACH-LIGA homocystein (german, austrian and swiss homocysteine society): consensus paper on the rational clinical use of homocysteine, folic acid and B‑vitamins in cardiovascular and thrombotic diseases: guidelines and recommendations. Clin Chem Lab Med 41:1392–1403 PubMed Stanger O, Herrmann W, Pietrzik K et al (2003) DACH-LIGA homocystein (german, austrian and swiss homocysteine society): consensus paper on the rational clinical use of homocysteine, folic acid and B‑vitamins in cardiovascular and thrombotic diseases: guidelines and recommendations. Clin Chem Lab Med 41:1392–1403 PubMed
36.
Zurück zum Zitat Krebs J, Fleischli S, Stoyanov J, Pannek J (2019) Effects of oral immunomodulation therapy on urinary tract infections in individuals with chronic spinal cord injury—A retrospective cohort study. Neurourol Urodyn 38:346–352 PubMedCrossRef Krebs J, Fleischli S, Stoyanov J, Pannek J (2019) Effects of oral immunomodulation therapy on urinary tract infections in individuals with chronic spinal cord injury—A retrospective cohort study. Neurourol Urodyn 38:346–352 PubMedCrossRef
37.
Zurück zum Zitat Hachen HJ (1990) Oral immunotherapy in paraplegic patients with chronic urinary tract infections: a double-blind, placebo-controlled trial. J Urol 143:759–762 (discussion 62–3) PubMedCrossRef Hachen HJ (1990) Oral immunotherapy in paraplegic patients with chronic urinary tract infections: a double-blind, placebo-controlled trial. J Urol 143:759–762 (discussion 62–3) PubMedCrossRef
38.
Zurück zum Zitat Huttner A, Hatz C, van den Dobbelsteen G et al (2017) Safety, immunogenicity, and preliminary clinical efficacy of a vaccine against extraintestinal pathogenic Escherichia coli in women with a history of recurrent urinary tract infection: a randomised, single-blind, placebo-controlled phase 1b trial. Lancet Infect Dis 17:528–537 (May) PubMedCrossRef Huttner A, Hatz C, van den Dobbelsteen G et al (2017) Safety, immunogenicity, and preliminary clinical efficacy of a vaccine against extraintestinal pathogenic Escherichia coli in women with a history of recurrent urinary tract infection: a randomised, single-blind, placebo-controlled phase 1b trial. Lancet Infect Dis 17:528–537 (May) PubMedCrossRef
39.
Zurück zum Zitat Sunden F, Hakansson L, Ljunggren E, Wullt B (2010) Escherichia coli 83972 bacteriuria protects against recurrent lower urinary tract infections in patients with incomplete bladder emptying. J Urol 184:179–185 PubMedCrossRef Sunden F, Hakansson L, Ljunggren E, Wullt B (2010) Escherichia coli 83972 bacteriuria protects against recurrent lower urinary tract infections in patients with incomplete bladder emptying. J Urol 184:179–185 PubMedCrossRef
40.
Zurück zum Zitat Darouiche RO, Green BG, Donovan WH et al (2011) Multicenter randomized controlled trial of bacterial interference for prevention of urinary tract infection in patients with neurogenic bladder. Urology 78:341–346 PubMedCrossRef Darouiche RO, Green BG, Donovan WH et al (2011) Multicenter randomized controlled trial of bacterial interference for prevention of urinary tract infection in patients with neurogenic bladder. Urology 78:341–346 PubMedCrossRef
41.
Zurück zum Zitat Toh SL, Boswell-Ruys CL, Lee BSB, Simpson JM, Clezy KR (2017) Probiotics for preventing urinary tract infection in people with neuropathic bladder. Cochrane Database Syst Rev 9:Cd10723 PubMed Toh SL, Boswell-Ruys CL, Lee BSB, Simpson JM, Clezy KR (2017) Probiotics for preventing urinary tract infection in people with neuropathic bladder. Cochrane Database Syst Rev 9:Cd10723 PubMed
42.
Zurück zum Zitat Pannek J, Pannek-Rademacher S, Wollner J (2015) Use of complementary and alternative medicine in persons with spinal cord injury in Switzerland: a survey study. Spinal Cord 53:569–572 PubMedCrossRef Pannek J, Pannek-Rademacher S, Wollner J (2015) Use of complementary and alternative medicine in persons with spinal cord injury in Switzerland: a survey study. Spinal Cord 53:569–572 PubMedCrossRef
43.
Zurück zum Zitat Jonas WB, Kaptchuk TJ, Linde K (2003) A critical overview of homeopathy. Ann Intern Med 4(138):393–399 CrossRef Jonas WB, Kaptchuk TJ, Linde K (2003) A critical overview of homeopathy. Ann Intern Med 4(138):393–399 CrossRef
44.
Zurück zum Zitat Pannek J, Pannek-Rademacher S, Jus MS, Wollner J, Krebs J (2019) Usefulness of classical homeopathy for the prophylaxis of recurrent urinary tract infections in individuals with chronic neurogenic lower urinary tract dysfunction. J Spinal Cord Med 42:453–459 PubMedCrossRef Pannek J, Pannek-Rademacher S, Jus MS, Wollner J, Krebs J (2019) Usefulness of classical homeopathy for the prophylaxis of recurrent urinary tract infections in individuals with chronic neurogenic lower urinary tract dysfunction. J Spinal Cord Med 42:453–459 PubMedCrossRef
45.
Zurück zum Zitat Wang J, Zhai Y, Wu J, Zhao S, Zhou J, Liu Z (2016) Acupuncture for chronic urinary retention due to spinal Cord injury: a systematic review. Evid Based Complement Alternat Med 2016:9245186 PubMedPubMedCentral Wang J, Zhai Y, Wu J, Zhao S, Zhou J, Liu Z (2016) Acupuncture for chronic urinary retention due to spinal Cord injury: a systematic review. Evid Based Complement Alternat Med 2016:9245186 PubMedPubMedCentral
46.
Zurück zum Zitat Honjo H, Naya Y, Ukimura O, Kojima M, Miki T (2000) Acupuncture on clinical symptoms and urodynamic measurements in spinal-cord-injured patients with detrusor hyperreflexia. Urol Int 65:190–195 PubMedCrossRef Honjo H, Naya Y, Ukimura O, Kojima M, Miki T (2000) Acupuncture on clinical symptoms and urodynamic measurements in spinal-cord-injured patients with detrusor hyperreflexia. Urol Int 65:190–195 PubMedCrossRef
47.
Zurück zum Zitat Aune A, Alraek T, LiHua H, Baerheim A (1998) Acupuncture in the prophylaxis of recurrent lower urinary tract infection in adult women. Scand J Prim Health Care 16:37–39 PubMedCrossRef Aune A, Alraek T, LiHua H, Baerheim A (1998) Acupuncture in the prophylaxis of recurrent lower urinary tract infection in adult women. Scand J Prim Health Care 16:37–39 PubMedCrossRef
48.
Zurück zum Zitat Alraek T, Baerheim A, Birch S (2016) Acupuncture points used in the prophylaxis against recurrent uncomplicated cystitis, patterns identified and their possible relationship to physiological measurements. Chin J Integr Med 22:510–517 PubMedCrossRef Alraek T, Baerheim A, Birch S (2016) Acupuncture points used in the prophylaxis against recurrent uncomplicated cystitis, patterns identified and their possible relationship to physiological measurements. Chin J Integr Med 22:510–517 PubMedCrossRef
49.
Zurück zum Zitat Azeredo J, Sutherland IW (2008) The use of phages for the removal of infectious biofilms. Curr Pharm Biotechnol 9:261–266 PubMedCrossRef Azeredo J, Sutherland IW (2008) The use of phages for the removal of infectious biofilms. Curr Pharm Biotechnol 9:261–266 PubMedCrossRef
50.
Zurück zum Zitat Viertel TM, Ritter K, Horz HP (2014) Viruses versus bacteria-novel approaches to phage therapy as a tool against multidrug-resistant pathogens. J Antimicrob Chemother 69:2326–2336 PubMedCrossRef Viertel TM, Ritter K, Horz HP (2014) Viruses versus bacteria-novel approaches to phage therapy as a tool against multidrug-resistant pathogens. J Antimicrob Chemother 69:2326–2336 PubMedCrossRef
52.
Zurück zum Zitat Khawaldeh A, Morales S, Dillon B et al (2011) Bacteriophage therapy for refractory Pseudomonas aeruginosa urinary tract infection. J Med Microbiol 60:1697–1700 PubMedCrossRef Khawaldeh A, Morales S, Dillon B et al (2011) Bacteriophage therapy for refractory Pseudomonas aeruginosa urinary tract infection. J Med Microbiol 60:1697–1700 PubMedCrossRef
53.
Zurück zum Zitat Leitner L, Ujmajuridze A, Chanishvili N et al (2021) Intravesical bacteriophages for treating urinary tract infections in patients undergoing transurethral resection of the prostate: a randomised, placebo-controlled, double-blind clinical trial. Lancet Infect Dis 21:427–436 PubMedCrossRef Leitner L, Ujmajuridze A, Chanishvili N et al (2021) Intravesical bacteriophages for treating urinary tract infections in patients undergoing transurethral resection of the prostate: a randomised, placebo-controlled, double-blind clinical trial. Lancet Infect Dis 21:427–436 PubMedCrossRef
54.
Zurück zum Zitat Abrams P, Hashim H, Tomson C, Macgowan A, Skews R, Warren K (2017) The use of intravesical gentamicin to treat recurrent urinary tract infections in lower urinary tract dysfunction. Neurourol Urodyn 36:2109–2116 PubMedCrossRef Abrams P, Hashim H, Tomson C, Macgowan A, Skews R, Warren K (2017) The use of intravesical gentamicin to treat recurrent urinary tract infections in lower urinary tract dysfunction. Neurourol Urodyn 36:2109–2116 PubMedCrossRef
55.
Zurück zum Zitat Cox L, He C, Bevins J, Clemens JQ, Stoffel JT, Cameron AP (2017) Gentamicin bladder instillations decrease symptomatic urinary tract infections in neurogenic bladder patients on intermittent catheterization. Can Urol Assoc J 11:E350–e4 PubMedPubMedCentralCrossRef Cox L, He C, Bevins J, Clemens JQ, Stoffel JT, Cameron AP (2017) Gentamicin bladder instillations decrease symptomatic urinary tract infections in neurogenic bladder patients on intermittent catheterization. Can Urol Assoc J 11:E350–e4 PubMedPubMedCentralCrossRef
56.
Zurück zum Zitat Iavazzo C, Athanasiou S, Pitsouni E, Falagas ME (2007) Hyaluronic acid: an effective alternative treatment of interstitial cystitis, recurrent urinary tract infections, and hemorrhagic cystitis? Eur Urol 51:1534–1540 (discussion 40–1) PubMedCrossRef Iavazzo C, Athanasiou S, Pitsouni E, Falagas ME (2007) Hyaluronic acid: an effective alternative treatment of interstitial cystitis, recurrent urinary tract infections, and hemorrhagic cystitis? Eur Urol 51:1534–1540 (discussion 40–1) PubMedCrossRef
57.
Zurück zum Zitat Damiano R, Quarto G, Bava I et al (2011) Prevention of recurrent urinary tract infections by intravesical administration of hyaluronic acid and chondroitin sulphate: a placebo-controlled randomised trial. Eur Urol 59:645–651 PubMedCrossRef Damiano R, Quarto G, Bava I et al (2011) Prevention of recurrent urinary tract infections by intravesical administration of hyaluronic acid and chondroitin sulphate: a placebo-controlled randomised trial. Eur Urol 59:645–651 PubMedCrossRef
58.
Zurück zum Zitat Cicek N, Yildiz N, Alpay H (2020) Intravesical hyaluronic acid treatment in recurrent urinary tract infections in children with spina bifida and neurogenic bladder. J Pediatr Urol 16(366):e1–e5 Cicek N, Yildiz N, Alpay H (2020) Intravesical hyaluronic acid treatment in recurrent urinary tract infections in children with spina bifida and neurogenic bladder. J Pediatr Urol 16(366):e1–e5
59.
Zurück zum Zitat Niël-Weise BS, van den Broek PJ (2005) Urinary catheter policies for long-term bladder drainage. Cochrane Database Syst Rev 25:Cd4201 Niël-Weise BS, van den Broek PJ (2005) Urinary catheter policies for long-term bladder drainage. Cochrane Database Syst Rev 25:Cd4201
60.
Zurück zum Zitat Fisher H, Oluboyede Y, Chadwick T et al (2018) Continuous low-dose antibiotic prophylaxis for adults with repeated urinary tract infections (AnTIC): a randomised, open-label trial. Lancet Infect Dis 18:957–968 PubMedPubMedCentralCrossRef Fisher H, Oluboyede Y, Chadwick T et al (2018) Continuous low-dose antibiotic prophylaxis for adults with repeated urinary tract infections (AnTIC): a randomised, open-label trial. Lancet Infect Dis 18:957–968 PubMedPubMedCentralCrossRef
61.
Zurück zum Zitat Poirier C, Dinh A, Salomon J, Grall N, Andremont A, Bernard L (2016) Prevention of urinary tract infections by antibiotic cycling in spinal cord injury patients and low emergence of multidrug resistant bacteria. Med Mal Infect 46:294–299 PubMedCrossRef Poirier C, Dinh A, Salomon J, Grall N, Andremont A, Bernard L (2016) Prevention of urinary tract infections by antibiotic cycling in spinal cord injury patients and low emergence of multidrug resistant bacteria. Med Mal Infect 46:294–299 PubMedCrossRef
62.
Zurück zum Zitat Salomon J, Denys P, Merle C et al (2006) Prevention of urinary tract infection in spinal cord-injured patients: safety and efficacy of a weekly oral cyclic antibiotic (WOCA) programme with a 2 year follow-up—an observational prospective study. J Antimicrob Chemother 57:784–788 PubMedCrossRef Salomon J, Denys P, Merle C et al (2006) Prevention of urinary tract infection in spinal cord-injured patients: safety and efficacy of a weekly oral cyclic antibiotic (WOCA) programme with a 2 year follow-up—an observational prospective study. J Antimicrob Chemother 57:784–788 PubMedCrossRef
63.
Zurück zum Zitat Dinh A, Hallouin-Bernard MC, Davido B et al (2020) Weekly sequential antibioprophylaxis for recurrent urinary tract infections among patients with neurogenic bladder: a randomized controlled trial. Clin Infect Dis 15(71):3128–3135 CrossRef Dinh A, Hallouin-Bernard MC, Davido B et al (2020) Weekly sequential antibioprophylaxis for recurrent urinary tract infections among patients with neurogenic bladder: a randomized controlled trial. Clin Infect Dis 15(71):3128–3135 CrossRef
64.
Zurück zum Zitat Salomon J, Schnitzler A, Ville Y et al (2009) Prevention of urinary tract infection in six spinal cord-injured pregnant women who gave birth to seven children under a weekly oral cyclic antibiotic program. Int J Infect Dis 13:399–402 PubMedCrossRef Salomon J, Schnitzler A, Ville Y et al (2009) Prevention of urinary tract infection in six spinal cord-injured pregnant women who gave birth to seven children under a weekly oral cyclic antibiotic program. Int J Infect Dis 13:399–402 PubMedCrossRef
65.
Zurück zum Zitat Michau A, Dinh A, Denys P et al (2016) Control cross-sectional study evaluating an antibiotic prevention strategy in 30 pregnancies under clean intermittent self-catheterization and review of literature. Urology 91:58–63 PubMedCrossRef Michau A, Dinh A, Denys P et al (2016) Control cross-sectional study evaluating an antibiotic prevention strategy in 30 pregnancies under clean intermittent self-catheterization and review of literature. Urology 91:58–63 PubMedCrossRef
66.
Zurück zum Zitat Galusca N, Charvier K, Courtois F, Rode G, Rudigoz RC, Ruffion A (2015) Antibioprophylaxy and urological management of women with spinal cord injury during pregnanc. Prog Urol 25:489–496 PubMedCrossRef Galusca N, Charvier K, Courtois F, Rode G, Rudigoz RC, Ruffion A (2015) Antibioprophylaxy and urological management of women with spinal cord injury during pregnanc. Prog Urol 25:489–496 PubMedCrossRef
67.
Zurück zum Zitat Böthig R, Fiebag K, Thietje R, Faschingbauer M, Hirschfeld S (2013) Morbidity of urinary tract infection after urodynamic examination of hospitalized SCI patients: the impact of bladder management. Spinal Cord 51:70–73 PubMedCrossRef Böthig R, Fiebag K, Thietje R, Faschingbauer M, Hirschfeld S (2013) Morbidity of urinary tract infection after urodynamic examination of hospitalized SCI patients: the impact of bladder management. Spinal Cord 51:70–73 PubMedCrossRef
68.
Zurück zum Zitat Tornic J, Wöllner J, Leitner L, Mehnert U, Bachmann LM, Kessler TM (2020) The challenge of asymptomatic Bacteriuria and symptomatic urinary tract infections in patients with neurogenic lower urinary tract dysfunction. J Urol 203:579–584 PubMedCrossRef Tornic J, Wöllner J, Leitner L, Mehnert U, Bachmann LM, Kessler TM (2020) The challenge of asymptomatic Bacteriuria and symptomatic urinary tract infections in patients with neurogenic lower urinary tract dysfunction. J Urol 203:579–584 PubMedCrossRef
69.
Zurück zum Zitat Aharony S, Przydacz M, Van Ba OL, Corcos J (2020) Does asymptomatic bacteriuria increase the risk of adverse events or modify the efficacy of intradetrusor onabotulinumtoxinA injections? Neurourol Urodyn 39:203–210 PubMedCrossRef Aharony S, Przydacz M, Van Ba OL, Corcos J (2020) Does asymptomatic bacteriuria increase the risk of adverse events or modify the efficacy of intradetrusor onabotulinumtoxinA injections? Neurourol Urodyn 39:203–210 PubMedCrossRef
70.
Zurück zum Zitat Leitner L, Sammer U, Walter M et al (2016) Antibiotic prophylaxis may not be necessary in patients with asymptomatic bacteriuria undergoing intradetrusor onabotulinumtoxin A injections for neurogenic detrusor overactivity. Sci Rep 12(6):33197 CrossRef Leitner L, Sammer U, Walter M et al (2016) Antibiotic prophylaxis may not be necessary in patients with asymptomatic bacteriuria undergoing intradetrusor onabotulinumtoxin A injections for neurogenic detrusor overactivity. Sci Rep 12(6):33197 CrossRef
71.
Zurück zum Zitat Weglinski L, Rouzaud C, Even A et al (2016) Prospective evaluation of antibiotic treatment for urological procedure in patients presenting with neurogenic bladder. Med Mal Infect 46:300–307 PubMedCrossRef Weglinski L, Rouzaud C, Even A et al (2016) Prospective evaluation of antibiotic treatment for urological procedure in patients presenting with neurogenic bladder. Med Mal Infect 46:300–307 PubMedCrossRef
72.
Zurück zum Zitat Chong JT, Klausner AP, Petrossian A et al (2015) Pre-procedural antibiotics for endoscopic urological procedures: Initial experience in individuals with spinal cord injury and asymptomatic bacteriuria. J Spinal Cord Med 38:187–192 PubMedPubMedCentralCrossRef Chong JT, Klausner AP, Petrossian A et al (2015) Pre-procedural antibiotics for endoscopic urological procedures: Initial experience in individuals with spinal cord injury and asymptomatic bacteriuria. J Spinal Cord Med 38:187–192 PubMedPubMedCentralCrossRef
73.
Zurück zum Zitat Paradella AC, Musegante AF, Brites C (2016) Comparison of different antibiotic protocols for asymptomatic bacteriuria in patients with neurogenic bladder treated with botulinum toxin A. Braz J Infect Dis 20:623–626 PubMedCrossRef Paradella AC, Musegante AF, Brites C (2016) Comparison of different antibiotic protocols for asymptomatic bacteriuria in patients with neurogenic bladder treated with botulinum toxin A. Braz J Infect Dis 20:623–626 PubMedCrossRef
Metadaten
Titel
Behandlung rezidivierender Harnwegsinfekte bei PatientInnen mit neurogener Blasenfunktionsstörung
verfasst von
Julia Neuenschwander
Prof. Dr. med. Jürgen Pannek
Publikationsdatum
25.05.2021
Verlag
Springer Vienna
Schlagwörter
Urologie
Neurologie
Erschienen in
Urologie in der Praxis / Ausgabe 3/2021
Print ISSN: 2661-8737
Elektronische ISSN: 2661-8745
DOI
https://doi.org/10.1007/s41973-021-00137-y

Weitere Artikel der Ausgabe 3/2021

Urologie in der Praxis 3/2021 Zur Ausgabe

Die Urologische Blickdiagnose

Blickdiagnose Urologie

Éditorial

Éditorial

News-Screen Urologie

News-Screen Urologie

www.gesundheitswirtschaft.at

Mit den beiden Medien ÖKZ und QUALITAS unterstützt Gesundheitswirtschaft.at das Gesundheitssystem durch kritische Analysen und Information, schafft Interesse für notwendige Veränderungen und fördert Initiative. Die ÖKZ ist seit 1960 das bekannteste Printmedium für Führungskräfte und Entscheidungsträger im österreichischen Gesundheitssystem. Die QUALITAS verbindet seit 2002 die deutschsprachigen Experten und Praktiker im Thema Qualität in Gesundheitseinrichtungen.

zur Seite

www.pains.at

P.A.I.N.S. bietet vielfältige und aktuelle Inhalte in den Bereichen Palliativmedizin, Anästhesie, Intensivmedizin, Notfallmedizin und Schmerzmedizin. Die Informationsplattform legt einen besonderen Schwerpunkt auf hochwertige Fortbildung und bietet Updates und ausgewählte Highlight-Beiträge aus Schmerznachrichten und Anästhesie Nachrichten.

zur Seite