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Erschienen in: European Surgery 6/2015

01.12.2015 | Original Article

The impact of advanced age on short- and long-term results after surgery for colorectal cancer

verfasst von: A. Dinnewitzer, C. Nawara, C. Augschöll, D. Neureiter, W. Hitzl, D. Öfner, T. Jäger

Erschienen in: European Surgery | Ausgabe 6/2015

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Summary

Background

Elderly patients with colorectal cancer are often seen as high-risk candidates for surgical treatment. This study was designed to characterize the outcomes of persons older than 80 years, compared with younger persons.

Methods

We investigated the short-term surgical outcome and long-term survival of octogenarians undergoing surgery for colorectal cancer in a retrospective analysis. All patients scheduled for surgical resection of colorectal adenocarcinoma at our institution from 2003 to 2010 were included.

Results

Our study included 699 patients, 126 (18 %) of whom were aged 80 years or older. Presentation with later stage disease was not seen more frequently in the octogenarians. Comorbidities showed a significant increase (p < 0.001) and more emergency operations had to be performed in the elderly (p = 0.015). The probability for postoperative complications was associated with advanced age (p = 0.009) and 1-year mortality was significantly higher in the octogenarians. Overall survival was shorter in octogenarians, but no difference was found in cancer-specific survival or time-to-recurrence, compared with patients under 80.

Conclusion

Surgery for colorectal cancer in the elderly is challenging due to preexisting comorbidities and an increased rate of emergency operations. Although the short-term outcome of octogenarians is worse compared to younger patients, the long-term oncological results remain satisfactory, leading to the assumption that advanced age alone should not be a contraindication for surgical therapy.
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Metadaten
Titel
The impact of advanced age on short- and long-term results after surgery for colorectal cancer
verfasst von
A. Dinnewitzer
C. Nawara
C. Augschöll
D. Neureiter
W. Hitzl
D. Öfner
T. Jäger
Publikationsdatum
01.12.2015
Verlag
Springer Vienna
Erschienen in
European Surgery / Ausgabe 6/2015
Print ISSN: 1682-8631
Elektronische ISSN: 1682-4016
DOI
https://doi.org/10.1007/s10353-015-0355-3