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01.07.2013 | original article | Ausgabe 13-14/2013

Wiener klinische Wochenschrift 13-14/2013

The early prediction of neonatal morbidity and mortality in singleton small for gestational age infants with a birthweight < 1,500 g

Zeitschrift:
Wiener klinische Wochenschrift > Ausgabe 13-14/2013
Autoren:
MD Monika Olischar, Dr. Agnes Messerschmidt, Dr. Andreas Repa, Dr. Katrin Klebermasz-Schrehof, Dr. Michael Weber, Prof. Arnold Pollak, Prof. Harald Leitich

Summary

Objective

Identify factors for discrimination of “high” and “low risk” small for gestational age infants.

Study design

Singleton infants born small for gestational age with a birthweight  <1,500 g between 1999 and 2007 were included. Maternal, placental, and infant related factors were analyzed with regard to mortality and morbidity. Patients who died or suffered from complications were defined “high risk” as opposed to “low risk”. Parameters associated with “high risk” were identified and an equation established to predict the minimal expected probability to die or suffer from neonatal morbidity.

Results

Around 231 patients showed a mortality rate of 12.6 %, respiratory distress syndrome in 35.5 %, necrotizing enterocolitis in 8.2 % and neurological morbidities in 6.5 %. Of these, 58.9 % survived without complications. The factors for discrimination of “high” and “low risk” were Z-score of birth weight, gestational age, and pH.

Conclusion

We facilitate prognostication by classifying small for gestational age preterms into “low” and “high risk”.

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