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Erschienen in: Spektrum der Augenheilkunde 1/2024

24.08.2021 | review article

The clinical importance of uveomeningeal syndromes

verfasst von: Dimitrios Kalogeropoulos, MD, MSc, PhD candidate, Ioannis Asproudis, Maria Stefaniotou, Marilita Moschos, Soon Wai Ch’ng, Spyridon Konitsiotis, Constantina Gartzonika, Chris Kalogeropoulos

Erschienen in: Spektrum der Augenheilkunde | Ausgabe 1/2024

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Summary

Background

The aim of this review is to summarize the current knowledge about clinical findings, diagnostic work-up, and treatment of uveomeningeal syndromes, with special emphasis on the uveitic features of these pathologies.

Materials and methods

A thorough literature search was performed in the PubMed database. An additional search was conducted in Google Scholar to complete the collected items.

Results

Uveomeningeal syndromes is an umbrella term for a group of pathologies that affect the uvea, retina, and meninges. They present with a plethora of clinical features ranging from meningitis and meningoencephalitis to uveitis. A wide spectrum of infectious, inflammatory, and neoplastic conditions have been associated with these clinical entities. However, these syndromes are probably an autoimmune and inflammatory disorder, as they mainly cause inflammation to the ocular and neurologic body structures. However, less frequently, infectious uveitis with concomitant acute or chronic meningoencephalitis can also lead to uveomeningeal syndrome. Primary vitreoretinal (and central nerve system) lymphoma, as well as paraneoplastic disorders, should also be part of the differential diagnosis, before diagnosing a case as uveomeningeal syndrome.

Conclusion

The diagnostic approach in a patient with uveomeningeal syndrome can be extremely challenging. Thorough ophthalmic and medical history together with a detailed ophthalmic and systematic assessment forms the cornerstone of a holistic approach to these cases. A systematic algorithm is necessary for a methodical diagnostic and treatment approach, to organize an effective management plan for patients with uveomeningeal syndromes.
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Metadaten
Titel
The clinical importance of uveomeningeal syndromes
verfasst von
Dimitrios Kalogeropoulos, MD, MSc, PhD candidate
Ioannis Asproudis
Maria Stefaniotou
Marilita Moschos
Soon Wai Ch’ng
Spyridon Konitsiotis
Constantina Gartzonika
Chris Kalogeropoulos
Publikationsdatum
24.08.2021
Verlag
Springer Vienna
Erschienen in
Spektrum der Augenheilkunde / Ausgabe 1/2024
Print ISSN: 0930-4282
Elektronische ISSN: 1613-7523
DOI
https://doi.org/10.1007/s00717-021-00500-x

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