Skip to main content
main-content

Tipp

Weitere Artikel dieser Ausgabe durch Wischen aufrufen

01.12.2012 | Original Article | Ausgabe 6/2012

European Surgery 6/2012

Surgical treatment of synchronous and metachronous hepatic–and pulmonary colorectal cancer metastases —the Copenhagen experience

Zeitschrift:
European Surgery > Ausgabe 6/2012
Autoren:
MD Peter Stemann Andersen, MD Kåre Hornbech, MD Peter Nørgaard Larsen, MD Jesper Ravn, dr.med Andre Wettergren

Summary

Background

The surgical treatment of patients with isolated colorectal hepatic- or pulmonary metastases is well established with a 5-year survival in the range of 40–50 %. In contrast the treatment of patients with both hepatic- and pulmonary metastases remains controversial. We here present our initial results of patients who underwent both hepatic- and pulmonary resections for colorectal metastases with emphasis on post-operative complications and long-term survival.

Methods

The files of patients with metastasising colorectal cancer who underwent both hepatic- and pulmonary metastasectomy during 2003–2010 were reviewed retrospectively. Estimated overall survival and 1-, 3-, and 5-year survival rates were calculated by the method of Kaplan Meier. The log-rank test was used to compare patients survival for synchronous and metachronous metastases. A p value < 0.05 was considered significant.

Results

Nineteen patients were identified (9F/10M) with a median age of 63 years. Ten patients (53 %) presented with synchronous metastases and nine patients (47 %) with metachronous metastases. Only minor medical- and surgical complications were reported subsequent surgery. The 30-day mortality was zero. From time of resection of the primary colorectal tumour the estimated 5-year survival rate was 48.5 % with a median survival of 47 months. There were no difference in long-term survival between synchronous and metachronous metastases (p> 0.05).

Conclusions

The present study has demonstrated that resection of both hepatic and pulmonary colorectal metastases is safe and good long-term outcome can be obtained for selected patients. Thus, an aggressive surgical approach to patients with synchronous or metachronous hepatic and pulmonary metastases seems justified.

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

Literatur
Über diesen Artikel

Weitere Artikel der Ausgabe 6/2012

European Surgery 6/2012 Zur Ausgabe