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Erschienen in: Wiener Medizinische Wochenschrift 3-4/2013

01.02.2013 | main topic

Sulforaphane and related mustard oils in focus of cancer prevention and therapy

verfasst von: Ingrid Herr, PhD, Vladimir Lozanovski, Philipp Houben, Peter Schemmer, Markus W. Büchler

Erschienen in: Wiener Medizinische Wochenschrift | Ausgabe 3-4/2013

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Summary

The plant family Brassicaceae, formerly Cruciferae, contains mustard oil glycosides, from which mustard oils are enzymatically hydrolyzed. Mustard oils offer protection from pests, microorganisms and fungi. More than 120 different mustard oils with various biological functions are known. Since ancient times, these substances are used as natural antibiotics, antiviral drugs and antimycotics. The antioxidative effect of mustard oils contributes to protection from DNA damage. Epidemiological and experimental studies have shown preventive and therapeutic effects of crucifers or isolated substances thereof. Particularly well studied is the mustard oil sulforaphane, which is contained in high concentrations in broccoli and its sprouts. As has been shown in mice recently, sulforaphane also targets the most malignant cancer stem cells, which are not affected by conventional cancer treatments. Based on these promising results, the first prospective clinical studies with cancer patients and sulforaphane-enriched broccoli sprouts have now been initiated in the United States.
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Metadaten
Titel
Sulforaphane and related mustard oils in focus of cancer prevention and therapy
verfasst von
Ingrid Herr, PhD
Vladimir Lozanovski
Philipp Houben
Peter Schemmer
Markus W. Büchler
Publikationsdatum
01.02.2013
Verlag
Springer Vienna
Erschienen in
Wiener Medizinische Wochenschrift / Ausgabe 3-4/2013
Print ISSN: 0043-5341
Elektronische ISSN: 1563-258X
DOI
https://doi.org/10.1007/s10354-012-0163-3

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