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01.02.2017 | case report | Ausgabe 1/2017 Open Access

Spektrum der Augenheilkunde 1/2017

Severe reactive ischemic posterior segment inflammation in Acanthamoeba keratitis

Case report of a patient with Sjögren’s syndrome

Spektrum der Augenheilkunde > Ausgabe 1/2017
MD Christoph Palme, MD Bernhard Steger, MD Gertrud Haas, MD Barbara Teuchner, MD Nikolaos E. Bechrakis



We report on a case of Acanthamoeba keratitis (AK)-related reactive ischemic posterior segment inflammation following intraocular surgery in a patient with primary Sjögren’s syndrome (PSS).

Case report

A 48-year-old female patient with severe protracted AK underwent uneventful cataract surgery upon development of a corneal scar. Four weeks postoperatively, she experienced a rapid loss of vision to no light perception. Central retinal artery occlusion and ischemic optic neuropathy could be excluded, and a diagnosis of PSS was made. The condition remained unresponsive to systemic steroid treatment and ultimately led to enucleation of the globe. Histologic work-up revealed ischemic posterior segment inflammation and Acanthamoeba cysts in the corneal stroma.


Autoimmune disease may be a risk factor for AK-related severe reactive ischemic posterior segment inflammation, and intraocular surgery can be a trigger to its manifestation.

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