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Wiener klinische Wochenschrift

Erschienen in:

01.05.2013 | original article

Resistance index in mural arteries of thickened bowel wall: predictive value for Crohn disease activity assessment in pediatric patients

verfasst von: I. Sjekavica, V. Barbarić-Babić, V. Šunjara, M. Kralik, I. Senečić-Čala, M. Dujšin, R. Štern-Padovan

Erschienen in: Wiener klinische Wochenschrift | Ausgabe 9-10/2013

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Summary

Objective

To define reliable Doppler parameters in mural arteries of affected bowel loops for quantitative assessment of Crohn disease (CD) activity in pediatric population and compare Doppler parameters with Pediatric Crohn Disease Activity Index (PCDAI).

Patients and methods

Thirty-four pediatric patients (7 with inactive, 27 with active disease of different severity; 13 male and 21 female; mean age 13; range 7–18) with CD were prospectively evaluated by Doppler ultrasound (DUS) of affected bowel segments. Using semiquantitative color and power Doppler assessment of vascularization of thickened bowel wall and mesentery, patients were divided in four grades. Spectral measurements (peak systolic velocity (PSV), end diastolic velocity (EDV), resistance index (RI)) of mural arteries were compared with PCDAI.

Results

There was a significant difference in distribution of semiquantitative color values between inactive and active group. PSV and EDV values showed no significant difference between inactive and active group, while mean RI was significantly higher in the inactive group. RI was also significantly negatively correlated with PCDAI.

Conclusion

Intensity of color and power Doppler signals and RI measurement of mural arteries in thickened bowel wall is linked to CD activity and therefore might be of use in pediatric patients.

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Titel: Resistance index in mural arteries of thickened bowel wall: predictive value for Crohn disease activity assessment in pediatric patients
verfasst von: I. Sjekavica
V. Barbarić-Babić
V. Šunjara
M. Kralik
I. Senečić-Čala
M. Dujšin
R. Štern-Padovan
Publikationsdatum: 01.05.2013
Verlag: Springer Vienna
Erschienen in: Wiener klinische Wochenschrift / Ausgabe 9-10/2013
Print ISSN: 0043-5325
Elektronische ISSN: 1613-7671
DOI: https://doi.org/10.1007/s00508-013-0357-8

Springer Medizin Österreich

Summary

Objective

Patients and methods

Results

Conclusion

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