A 42-year-old woman been suffering from multiple sclerosis for 2 years received an emergency laparotomy because of acute pancreatitis. Anesthesia was induced with propofol and fentanil and maintained with nitrous oxide and sevoflurane. Rocuronium was used for tracheal intubation and muscle relaxation. Train of four ratio was monitored for tracing muscle relaxation. Three days later the patient was operated again due to abdominal cavity infection and followed up with “open abdomen strategy” receiving general anesthesia with 3 days intervals. In all of the six general anesthesia procedures in 18 days the patient was successfully reversed with sugammadex.